ID B3M8I2_DROAN Unreviewed; 2715 AA.
AC B3M8I2;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 2.
DT 24-JAN-2024, entry version 97.
DE SubName: Full=Uncharacterized protein, isoform J {ECO:0000313|EMBL:EDV38917.2};
GN Name=Dana\GF24755 {ECO:0000313|EMBL:EDV38917.2};
GN Synonyms=dana_GLEANR_9453 {ECO:0000313|EMBL:EDV38917.2};
GN ORFNames=GF24755 {ECO:0000313|EMBL:EDV38917.2};
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217 {ECO:0000313|EMBL:EDV38917.2, ECO:0000313|Proteomes:UP000007801};
RN [1] {ECO:0000313|EMBL:EDV38917.2, ECO:0000313|Proteomes:UP000007801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14024-0371.13 {ECO:0000313|Proteomes:UP000007801};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH902618; EDV38917.2; -; Genomic_DNA.
DR RefSeq; XP_001956111.2; XM_001956075.2.
DR EnsemblMetazoa; FBtr0390646; FBpp0350161; FBgn0101748.
DR GeneID; 6507385; -.
DR KEGG; dan:6507385; -.
DR eggNOG; KOG1473; Eukaryota.
DR eggNOG; KOG1632; Eukaryota.
DR HOGENOM; CLU_000284_0_0_1; -.
DR OrthoDB; 2878869at2759; -.
DR Proteomes; UP000007801; Unassembled WGS sequence.
DR GO; GO:0016589; C:NURF complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd05509; Bromo_gcn5_like; 1.
DR CDD; cd15559; PHD1_BPTF; 1.
DR CDD; cd15560; PHD2_3_BPTF; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR038028; BPTF.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR028942; WHIM1_dom.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45975; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR PANTHER; PTHR45975:SF2; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF00628; PHD; 3.
DR Pfam; PF15612; WHIM1; 1.
DR Pfam; PF15613; WSD; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00249; PHD; 3.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 3.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007801};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 190..250
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 341..388
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2527..2592
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2619..2689
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1019..1046
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1080..1109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1409..1430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1568..1595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1995..2021
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2151..2170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2198..2278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2306..2362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2421..2475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..34
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..97
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..137
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..535
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1019..1044
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1092..1106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2198..2223
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2318..2338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2339..2353
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2434..2459
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2715 AA; 303192 MW; 70612EBDAEEDEDC8 CRC64;
MSGRGSRKRG RPPKTPNERT SGRFDYKLLK KPKYLSEGKS QPSTPSASRG ISPQSDEGSR
SSNNNHNRSS RGSAASKRGR GRKSNVQANT SSYSGRKGYE SEYHYGSDFG DSEEEKSDNE
DDMLLTPSDD ESLDAANESE SEFSVCSFNQ NGGVGRPSRP PSPEPVWLQE GRQYAALNLP
DSSEDLSLPN THVLRALSIY EVLRRFRHLV RLSPFRFEDF AAAMACDEQS ALLTDVHIML
LKAILREEDA QGTHFGPLDQ KDTVNISLYL IDAITWPEVL RSYVESDKSF DRNVYHILSR
TEYPYTSVEN RLEVLQFLAD QFLTANSVRD VMLQEGPIHY DDHCRVCHRL GDLLCCETCP
AVYHLECVDP PMNDVPTEDW QCGLCRSHKV TGVVDCVLPQ EKQGVLIRHD SLGVDRHGRR
YWFIARRIFV EDQTDCTCWY YSTTSKLKLL LKRLDAEELE PRLHAQICER REEIERQMKL
TETLTNEHKH SKRSIIEMEQ EATNEILDKD AGAEEDDEEA KSDEAAKKTE ETKMVTRQKT
TQMNNGTLYF KLGMEQGFKN YVNQYSSNTI ALNKPQRNEE RDKRRHLSHK FSLTTASDFK
WIGITMGSTE NMITTLRQTL ISFESNIAAS FLNPNWVINK KVWNAAVMNA RRATDFAAVL
MLFQASLKSV VFANVWHEQL GHTSLQRITS AEREERKKLE KREKRERDDE EERNRLAFNY
IKYSLGLKHQ VWKQKGEEYR VHGQWGWLWL SSSRRCGVRA RRAQPLTHNR IYVHYTMGAE
EAAVNEIVLV DPRTQLFMQQ CETSNVDGQV CHYLPEQYTN VKVIEDVKDK VKGHIDVSRA
LTTPGRTYYP KVARKSRLDD LLERRVKLAE VEEQIASKVA ADVKPLVISA PNPANAHQTY
LEKRLLRLTE AAVKGGPANV NLELVNSLAK QIQTVRLQFS QLNRFAKTFG CYTKECNTNS
NAVSQITQNT CYSPLCLQKA RAKKELLLLL RKAHTAGNGS KETVAAILGA VKKPSILEQK
LTEGKRESTQ LAADESEDGK GPESEAPLDL LQDWEQARAH AVTFSDLFLS ECLQLETDAA
GNPKIKEEDD PSTGSTTTAG DSNTQDSDKM DFIESMDVCS NVEVESTEDS IVAGLNAASG
AAAEDTDTAP GWRRKRNQKS KKAYIGTKDV LDQTLDKDIP LNKQNRRFPI NARPIKREPV
KKYEREYFEN GSERVYSTKS ASGRVYLISD SAKLYEQAVK SEDKSTPVVK KASYSRYPLI
SNFLTHKKKR SLLVLPRYEL LKLARLGGKS TANGFHHGAK NNSIWQYQCS RPLFRTCWAY
RTSNATTLSS LALQLRILWT CLRWDDMIAK PPSTDGKHQV TTDTEIVTLE LLKLRHAGRY
GEKTSYLRRK VVIPLEMPKT IREVTSIRSG LRKRKRAESP QPTEPQISEE WVEEDKLELW
EIKFMGEKQE KARLSTVTRS VASRQLEASG GSLAGTSTNG TTIGVGGRIQ LAPKTSEDVK
EKMEQQLKLQ RAVHQQRKVV GAGDITRSVT PVKGQVIGSR RVIVKNPDGT TRIIQQAVTQ
VARSSAAGNS ATATSSPTVS NASSTQTNPS STPHKVQIIR GPDGKVSVRG LNPGQQLVQM
PDGKLHVLTT TPASNANTPG NKVNKVIKTV SATSSPAVSG ATAATSASGT PVIKQIAVKH
VAKTPGAQAI ATSQRVALPI AQIKNKLLLA QQQQSSASTS GTSSPAVQKI VSKVVSTTPG
QNLQQVFQVQ SGSKLVVGQN AQGQKVIIST SSAQQQVASP VQQQQQQQIV QTQVLAQPVQ
QSPQQQTQQI SVNQVGAQPT QKVIQQIVNT SNVQQQIVLG GQRIILSPGQ TIVTQRNVPQ
SQALQMVQQQ IQTQQQQQQQ QQQVVAQPQQ QFVVQTNQVV SSPSTQTKLV KQLVVQQQQA
VQPAAEEKPQ VNSTGEAGET AMQQVLVPNS TLAQQLAQGK LQVATVNGQQ VIVKPLGNNQ
AQIVAHIKHQ GDGNAHIVTN NAAPQASPQN SPVKQQQQQQ TITAQSPQQQ VVIQQQQQQI
AQPAATNFDC SSSSVVAQAV TGQTPAMSVE ESLLQNQPPG TVIKCVTAQV LQTEHGPRIV
LQGLVGNDFT AQQLQLVQTQ VKQQLMKAQE SNGKLGVLGP TKIYLAVQPE TTNQSQPPPL
TPVHQSAAHQ QTNIDSDAAA LTTTYEASPT IRINSINSAV SSEQEHSTSA QTDKTNITIN
HKPSVGTPPL LEGLEPNESM AVEDHNASAT GPADGEAGLE EDKQGDGDGE GDGDGFVVTS
GYIQESINNA LKQGNLSPEL EEKLVNMRKH QQDQQDDWEL SSRGSATDDG ITPSRRRTIS
RQQNDDTEWK VRAPSRRPNA MTTSNQFNRT IKKTRRQTEE VSDLGEPKQT QLDRHKEMLK
KTILRKRSLL ERNLQNEIRD EVQTKVQRHV RPMSVASPDE HSENERSFSD RRSESNSELK
RSEPNAQNSR IGVGRPKKMI RKKEKLYCVC RTPYDDTKFY VGCDLCSNWF HGDCVNISEE
ASKKLSEFIC TDCKKARETQ QLYCSCRQPY DESQFYICCD KCQDWFHGRC VGILQSEAEF
IDEYVCPECQ RKTDANAANM KILTSNEIDE LKIVIKAIQS HKSAWPFMEP VDPDEAPDYY
KVIKEPMDLK QMESKLESNA YTKLAEFIGD MTKIFDNCRY YNPKESSFYK CAEALESYFV
QKIKTFRENV LGQSN
//
