ID B3M8Z9_DROAN Unreviewed; 838 AA.
AC B3M8Z9;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=NF-X1-type domain-containing protein {ECO:0000259|SMART:SM00438};
GN Name=Dana\GF24744 {ECO:0000313|EMBL:EDV38943.1};
GN Synonyms=dana_GLEANR_9443 {ECO:0000313|EMBL:EDV38943.1};
GN ORFNames=GF24744 {ECO:0000313|EMBL:EDV38943.1};
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217 {ECO:0000313|EMBL:EDV38943.1, ECO:0000313|Proteomes:UP000007801};
RN [1] {ECO:0000313|EMBL:EDV38943.1, ECO:0000313|Proteomes:UP000007801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14024-0371.13 {ECO:0000313|Proteomes:UP000007801};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SIMILARITY: Belongs to the NFX1 family.
CC {ECO:0000256|ARBA:ARBA00007269}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH902618; EDV38943.1; -; Genomic_DNA.
DR RefSeq; XP_001956137.1; XM_001956101.2.
DR AlphaFoldDB; B3M8Z9; -.
DR STRING; 7217.B3M8Z9; -.
DR EnsemblMetazoa; FBtr0129444; FBpp0127936; FBgn0101737.
DR GeneID; 6507375; -.
DR KEGG; dan:6507375; -.
DR eggNOG; KOG1952; Eukaryota.
DR HOGENOM; CLU_014224_0_0_1; -.
DR InParanoid; B3M8Z9; -.
DR OMA; KCQSVCH; -.
DR OrthoDB; 1412at2759; -.
DR PhylomeDB; B3M8Z9; -.
DR Proteomes; UP000007801; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06008; NF-X1-zinc-finger; 5.
DR CDD; cd16697; RING-CH-C4HC3_NFXL1; 1.
DR InterPro; IPR034078; NFX1_fam.
DR InterPro; IPR000967; Znf_NFX1.
DR PANTHER; PTHR12360:SF1; NF-X1-TYPE ZINC FINGER PROTEIN NFXL1; 1.
DR PANTHER; PTHR12360; NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1; 1.
DR Pfam; PF01422; zf-NF-X1; 10.
DR SMART; SM00438; ZnF_NFX; 10.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007801};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT TRANSMEM 816..836
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 194..212
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 247..275
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 301..329
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 355..374
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 407..426
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 434..453
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 490..508
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 593..622
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 632..650
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 700..721
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT COILED 759..786
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 838 AA; 93756 MW; 07D6213A9138AA56 CRC64;
MEKFNKAQAK NLAAAQKLVE TYASSSEDEG ELDEKQILDQ LYKHYQPSDG SSKDAARTAT
FLENTLHSGA ATCLICIGSI RRVEAIWSCE SCYCFFHLNC IQRWANDSMM QMKVKAAEQQ
NGQGHYNHLG EFVPPKRQKS LHWCCPQCRR DYLPADKPTQ YNCFCGKEAN PQAQPFLVPH
SCGEICGKLL QPKCGHDCKL LCHPGPCPPC AQQANVSCLC GKSPPRSMRC IDKQWRCQQP
CKELLACGKH KCKQECHRPG QCPPCNSKSL QPCECQRESK MVNCSDRKWK CQNVCGTPFA
CGLHICEKVC HAGPCSGGEC PFQVRSCPCG KNTQVGPCSE AEETCGDTCQ KLLSCGQHTC
TQRCHRGPCI SCPVRTKKKC RCGLHEKELP CSKEFACETK CKQMRDCGKH ACNRKCCGDQ
CPPCEKICGK QLSCNKHKCQ SVCHNGPCYP CKLESQINCR CGKTKRSVPC GRERSARIVC
LELCRISAKC HHAIKHRCHK GECPPCGQVC GLPNDTSGCG HICKSRCHEA IRVNKPSETR
PQAKKYEYKS QPHPRCDEGV VVTCIGGHEV ATWPCWNSRP SSCQRKCARQ LKCGNHKCSL
VCHSVANPKD MQQQLGCAPC EEGCTVPRPA GCTHSCPKGC HPPPCMPCNF VMKNKCHCGL
NQLVYKCSEY YDENGTVQEI IDRREKLRSC GNRCLKNYPC THRCTAICHS GKCPNPELCR
KKVRIFCNCK RLKQEIACDK HRAGQTSLAC DSHCKAEISR AQAAEQQDLE EKKRREEERN
RLELEKFEAK FGKRKHKERK TVDMGPPKSE INWQKISIYA VSLLTVLGAI AVAFYADS
//
