ID B3Q0M1_RHIE6 Unreviewed; 362 AA.
AC B3Q0M1;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=Citrate synthase {ECO:0000256|PIRNR:PIRNR001369};
GN Name=citA {ECO:0000313|EMBL:ACE91225.1};
GN OrderedLocusNames=RHECIAT_CH0002270 {ECO:0000313|EMBL:ACE91225.1};
OS Rhizobium etli (strain CIAT 652).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=491916 {ECO:0000313|EMBL:ACE91225.1, ECO:0000313|Proteomes:UP000008817};
RN [1] {ECO:0000313|EMBL:ACE91225.1, ECO:0000313|Proteomes:UP000008817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIAT 652 {ECO:0000313|EMBL:ACE91225.1,
RC ECO:0000313|Proteomes:UP000008817};
RA Gonzalez V., Acosta J.L., Santamaria R.I., Bustos P.,
RA Hernandez-Gonzalez I.L., Fernandez J.L., Diaz R., Flores M., Mora J.,
RA Palacios R., Davila G.;
RT "Genome diversity and DNA divergence of Rhizobium etli.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+);
CC Xref=Rhea:RHEA:16845, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57288; EC=2.3.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00000308};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate
CC from oxaloacetate: step 1/2. {ECO:0000256|ARBA:ARBA00004751}.
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|PIRNR:PIRNR001369,
CC ECO:0000256|RuleBase:RU003406}.
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DR EMBL; CP001074; ACE91225.1; -; Genomic_DNA.
DR AlphaFoldDB; B3Q0M1; -.
DR KEGG; rec:RHECIAT_CH0002270; -.
DR eggNOG; COG0372; Bacteria.
DR HOGENOM; CLU_025068_2_1_5; -.
DR UniPathway; UPA00223; UER00717.
DR Proteomes; UP000008817; Chromosome.
DR GO; GO:0036440; F:citrate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR CDD; cd06109; BsCS-I_like; 1.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR024176; Citrate_synthase_bac-typ.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF23; CITRATE SYNTHASE 2-RELATED; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PIRSF; PIRSF001369; Citrate_synth; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:ACE91225.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR001369}.
FT ACT_SITE 246
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
FT ACT_SITE 305
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
SQ SEQUENCE 362 AA; 38065 MW; FF5C3AD1ABF629B4 CRC64;
MKNGLEDVIA AETQLSDVNG EAGRLIIRGV SLDHLVAGGT YEGVAALLLD GLMERSFDQA
ELRGWLAQAR TKVFVHIQAA DAALLALPPV DAMRALIARL PDGDDFDTAL GLLAAPAVFL
PAILRLQRGQ KPIAPDVALS HAADILRMLT GKLPSKEQVA ALDTYLVTIS DHGLNASTFA
SRVIASTKAG LTSSVLAALS ALKGPLHGGA PGPVLDMLDA VGTAENAGCW LGEALDRGER
LMGFGHRIYR VRDPRADALK GALKPLIASG QVDSARGALA EAVEDAALAI LKARKPDRPL
DVNVEFYTAL LLEALGFPRQ AFTGVFAIGR TVGWLAHARE QALDGRLIRP RSVYIGPLPA
AA
//
