ID B3RL69_TRIAD Unreviewed; 566 AA.
AC B3RL69;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 82.
DE RecName: Full=Kringle domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TRIADDRAFT_51898 {ECO:0000313|EMBL:EDV29497.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV29497.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV29497.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV29497.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR EMBL; DS985241; EDV29497.1; -; Genomic_DNA.
DR RefSeq; XP_002108699.1; XM_002108663.1.
DR AlphaFoldDB; B3RL69; -.
DR STRING; 10228.B3RL69; -.
DR EnsemblMetazoa; TriadT51898; TriadP51898; TriadG51898.
DR GeneID; 6749127; -.
DR KEGG; tad:TRIADDRAFT_51898; -.
DR CTD; 6749127; -.
DR HOGENOM; CLU_481757_0_0_1; -.
DR InParanoid; B3RL69; -.
DR OrthoDB; 211181at2759; -.
DR PhylomeDB; B3RL69; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR CDD; cd00108; KR; 1.
DR Gene3D; 2.60.120.200; -; 2.
DR Gene3D; 2.40.20.10; Plasminogen Kringle 4; 1.
DR Gene3D; 3.10.250.10; SRCR-like domain; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000001; Kringle.
DR InterPro; IPR013806; Kringle-like.
DR InterPro; IPR018056; Kringle_CS.
DR InterPro; IPR038178; Kringle_sf.
DR InterPro; IPR000998; MAM_dom.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR24261:SF7; KRINGLE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24261; PLASMINOGEN-RELATED; 1.
DR Pfam; PF00051; Kringle; 1.
DR Pfam; PF00629; MAM; 2.
DR Pfam; PF00530; SRCR; 1.
DR PRINTS; PR00018; KRINGLE.
DR SMART; SM00130; KR; 1.
DR SMART; SM00137; MAM; 1.
DR SMART; SM00202; SR; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57440; Kringle-like; 1.
DR SUPFAM; SSF56487; SRCR-like; 1.
DR PROSITE; PS00021; KRINGLE_1; 1.
DR PROSITE; PS50070; KRINGLE_2; 1.
DR PROSITE; PS50060; MAM_2; 2.
DR PROSITE; PS50287; SRCR_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196};
KW Kringle {ECO:0000256|ARBA:ARBA00022572, ECO:0000256|PROSITE-
KW ProRule:PRU00121}; Reference proteome {ECO:0000313|Proteomes:UP000009022}.
FT DOMAIN 52..99
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 96..175
FT /note="Kringle"
FT /evidence="ECO:0000259|PROSITE:PS50070"
FT DOMAIN 197..302
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 309..466
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT REGION 537..566
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 268..278
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 566 AA; 63574 MW; 7EB40B6CD39A17AE CRC64;
MIRVIFFMEF IQVLMYFKLY GSGVDELAIF SGLYTNQYKD VWLTTTKSSA SSWRKADFHF
TPRQRRTRII LDGVLGRGHG GQIEVDYILI APYEVNCYTG NGVYYRGSIT KTISGYNCQQ
WKSNSPHNHS YSPSKYPDDD LSYNYCRNPG GKSSRPWCYT TNSQKVSEYC NIPSCYGGST
TTSYPLRTTT KSLGTQMQIT ESVQLSNYLS GVVEIKAHGV WGYMCAENLS NNTANVLCRQ
MGYYVSSRHY PGSPLNPQSS YQVASYNCTG LESSIEHCPS LRNTNGSYIC NNPQSVAVVA
CEQSSGNTTS CKFDKGFCGW SQPQRNLRMD WTWQSNYIFP GTNFKKSDPS IVVSTRNGFY
LDKAILRSPQ QSFQSSIVTI RFKYYLSSSG SVLTLKVDEN NKIIKKMSHD TNGAWISVYT
EVLPSVKTFT ISFVVMKTSS ESVIVGLDDI SIVGITPEPF VRKCIRATVA TALILGCILL
MICQICKKKP LRTIADENPP TYDQIVPPED ESPTEHDIIP DELTTNRIND NMEREQVRSC
PRNGTADRSI ISPNTVRSRE SLTAEV
//
