ID   B3RM16_TRIAD            Unreviewed;       504 AA.
AC   B3RM16;
DT   02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   02-SEP-2008, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   RecName: Full=VWFC domain-containing protein {ECO:0000259|PROSITE:PS50184};
GN   ORFNames=TRIADDRAFT_52199 {ECO:0000313|EMBL:EDV29619.1};
OS   Trichoplax adhaerens (Trichoplax reptans).
OC   Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC   Trichoplax.
OX   NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV29619.1, ECO:0000313|Proteomes:UP000009022};
RN   [1] {ECO:0000313|EMBL:EDV29619.1, ECO:0000313|Proteomes:UP000009022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV29619.1,
RC   ECO:0000313|Proteomes:UP000009022};
RX   PubMed=18719581; DOI=10.1038/nature07191;
RA   Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA   Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA   Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA   Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA   Rokhsar D.S.;
RT   "The Trichoplax genome and the nature of placozoans.";
RL   Nature 454:955-960(2008).
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DR   EMBL; DS985241; EDV29619.1; -; Genomic_DNA.
DR   RefSeq; XP_002108821.1; XM_002108785.1.
DR   AlphaFoldDB; B3RM16; -.
DR   STRING; 10228.B3RM16; -.
DR   EnsemblMetazoa; TriadT52199; TriadP52199; TriadG52199.
DR   GeneID; 6749302; -.
DR   KEGG; tad:TRIADDRAFT_52199; -.
DR   CTD; 6749302; -.
DR   eggNOG; ENOG502QQFQ; Eukaryota.
DR   HOGENOM; CLU_048288_1_0_1; -.
DR   InParanoid; B3RM16; -.
DR   OMA; TEPQRCC; -.
DR   OrthoDB; 3670395at2759; -.
DR   PhylomeDB; B3RM16; -.
DR   Proteomes; UP000009022; Unassembled WGS sequence.
DR   GO; GO:0036122; F:BMP binding; IBA:GO_Central.
DR   GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IBA:GO_Central.
DR   Gene3D; 6.20.200.20; -; 2.
DR   Gene3D; 2.10.70.10; Complement Module, domain 1; 1.
DR   InterPro; IPR045717; CHRDL1/2.
DR   InterPro; IPR001007; VWF_dom.
DR   PANTHER; PTHR46303; VWFC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR46303:SF1; VWFC DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00093; VWC; 3.
DR   SMART; SM00214; VWC; 4.
DR   SUPFAM; SSF57603; FnI-like domain; 4.
DR   PROSITE; PS01208; VWFC_1; 1.
DR   PROSITE; PS50184; VWFC_2; 4.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009022}.
FT   DOMAIN          31..96
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          115..184
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          193..258
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          300..365
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
SQ   SEQUENCE   504 AA;  56658 MW;  DF0DA420C03648B0 CRC64;
     MGDRFFIAGQ WLNSLSFMFN QLMKAYRSCG CQFGKDRYHC GQQWHPNLQP YGISYCILCT
     CKSNGAVECV DLKNKCEKPT CQNPSVLPGR CCPQCPDDPE VMAATSSPPA SYQQPTCHFL
     GKDYNSGQCW LSTDKRKLPT ATRDRQCIEC NCISGGVFCS PRKCPILKCK NQIQNNNTCC
     PVCKDESFKT EMSPCANMGN SYIKNSPWHP YFQPFGYSPC YECVCNKGEV NCRKIRCSEL
     NCNSQSSFSS GGCCSVCDKS SVTTYEESPN STIVPSNETS NLFQTAKPSL QMATTDKPKK
     SCKFDGLTKR HGQTWHPVLP PLGPMNCIDC HCQNGKVTCN PVICPTIYPC DNPKIIDGHC
     CKICSEIKDP QSTTTTVSTT PISTKTPPSA VIYRVYRYIS FPSQYNCKVQ LAIQNTQTEI
     FEIHSWKGNA SFRKFNLKLL TLDDFQYGNL LDLTGQFKYL GITTKDKVTE MEKLENQMKI
     ISCPCYCSHT MERLLTTLMI TKKY
//