ID B3RMR9_TRIAD Unreviewed; 535 AA.
AC B3RMR9;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=C2 domain-containing protein {ECO:0000259|PROSITE:PS50004};
GN ORFNames=TRIADDRAFT_20570 {ECO:0000313|EMBL:EDV27323.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV27323.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV27323.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV27323.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SIMILARITY: Belongs to the copine family.
CC {ECO:0000256|ARBA:ARBA00009048}.
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DR EMBL; DS985242; EDV27323.1; -; Genomic_DNA.
DR RefSeq; XP_002109157.1; XM_002109121.1.
DR AlphaFoldDB; B3RMR9; -.
DR STRING; 10228.B3RMR9; -.
DR EnsemblMetazoa; TriadT20570; TriadP20570; TriadG20570.
DR GeneID; 6750947; -.
DR KEGG; tad:TRIADDRAFT_20570; -.
DR CTD; 6750947; -.
DR eggNOG; KOG1327; Eukaryota.
DR HOGENOM; CLU_020452_3_2_1; -.
DR InParanoid; B3RMR9; -.
DR OMA; AHDSHSK; -.
DR OrthoDB; 672483at2759; -.
DR PhylomeDB; B3RMR9; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005544; F:calcium-dependent phospholipid binding; IBA:GO_Central.
DR GO; GO:0071277; P:cellular response to calcium ion; IBA:GO_Central.
DR CDD; cd04048; C2A_Copine; 1.
DR CDD; cd04047; C2B_Copine; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR037768; C2B_Copine.
DR InterPro; IPR045052; Copine.
DR InterPro; IPR010734; Copine_C.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10857; COPINE; 1.
DR PANTHER; PTHR10857:SF106; NICOTINIC RECEPTOR-ASSOCIATED PROTEIN 1; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF07002; Copine; 1.
DR SMART; SM00239; C2; 2.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50004; C2; 2.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022}.
FT DOMAIN 1..119
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 127..252
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
SQ SEQUENCE 535 AA; 59809 MW; 27CCFBF58F27F901 CRC64;
MATIPEEETC LTRVALYVSC KNLLKKDITS KSDPLVVFNV HNGCYWVEHQ RTEWIKNTSC
PEFVTPIVID FYFEKIQKVK LSVYDIDNDT ETLSDDDFLG EIETTLAKIV AAESYTDHLK
IPPHKVSQGT IHIRAEEMSD SRTNKILALK FKGQNLDKMD IFSKSDPYLE ICKLTSDSTY
LKIHRTEIIK NTLNPDWNLF LISVDTLCNG DYERSLQINC YDYDNNGSHD FIGSFATTLA
DMLGAKDNPI SYDCINPKKQ AKKNTYKNSG RIILQSVNII NDHSFLDYII GGCQINLAIG
IDFTISNKVA TNPKSLHYTG PNGKNQYLDA IKAVGNVCAD YDFDKLIPVF GFGAEIPPKN
KVSHAFPINF NATNPNVEGI EGVIAAYKNC ISKIQFYFPT NFAPIINHIA SFAANAAEDG
TASNYFILLL LTDGAITDTD KTKQALVKAS KLPMSVIIVG IGDADFTAMK DLDCDHGVLK
SSSGECALRD IVQFVSYKKF LQAPSDVLAQ HVLSEIPRQL RQHYLLSDME PMVRH
//
