ID B3RP79_TRIAD Unreviewed; 2749 AA.
AC B3RP79;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
GN ORFNames=TRIADDRAFT_53434 {ECO:0000313|EMBL:EDV27588.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV27588.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV27588.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV27588.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS985242; EDV27588.1; -; Genomic_DNA.
DR RefSeq; XP_002109422.1; XM_002109386.1.
DR STRING; 10228.B3RP79; -.
DR EnsemblMetazoa; TriadT53434; TriadP53434; TriadG53434.
DR GeneID; 6750637; -.
DR KEGG; tad:TRIADDRAFT_53434; -.
DR CTD; 6750637; -.
DR eggNOG; KOG0160; Eukaryota.
DR eggNOG; KOG0165; Eukaryota.
DR HOGENOM; CLU_000237_0_0_1; -.
DR InParanoid; B3RP79; -.
DR OMA; CCCCYIF; -.
DR OrthoDB; 53079at2759; -.
DR PhylomeDB; B3RP79; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd21223; CH_ASPM_rpt1; 1.
DR CDD; cd21224; CH_ASPM_rpt2; 1.
DR Gene3D; 1.20.5.190; -; 26.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR031549; ASH.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR22706:SF1; ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN ISOFORM X1; 1.
DR PANTHER; PTHR22706; UNCHARACTERIZED; 1.
DR Pfam; PF15780; ASH; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00612; IQ; 32.
DR SMART; SM00033; CH; 2.
DR SMART; SM00015; IQ; 54.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 12.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50096; IQ; 33.
PE 4: Predicted;
KW Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022}.
FT DOMAIN 629..763
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 810..959
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 193..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 337..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2505..2532
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 302..319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2749 AA; 324120 MW; 5AD72FCDFC241A2F CRC64;
MTDHCIRQEE NKENVASSEP FLKFVPFNGS QSAAQTQTED DHPVLVLKHF AQVPKLYFDK
VKVGRNKSIL LTIVNPSSKI HHIKVGKVSE LKGFTVNTTT LAIQPESQQQ LEITWNPKVV
GSVHDTLVLV SQNTHRLHVV LNGTAIESPH KKRTGRRLNQ QRHQVNNKLH KINTSKPNQK
AVLNTVIDVL QGDANKNNKS ESNQKVPTTT TTDAVQNDTK HQVQDEQTNV STSNHHQQYG
QEKFVNSQLV DFQSTNHDNQ LKKSHFGNHI IRETYTKSEL EDSLLGNVDS CPDDKEDNDN
NNRNNSNLNT QESNSKTEFK VRINKTIPNK CVKAKVNSES TAKNKTKQQQ LQSSQRKATL
PKTFNIRGIA QSRLRLISNG SAVKKTKTIS PFASQNNCYD DRWIDKQERG FTCWLNFILV
PCEDGVSMNK FVTKVDASTL ALTTDTTTRQ YHPTKDTLSY KNYENRKHLM MLRRAACILY
QSKPVRMVVE RITDAVKERK FTFKLDANIH SDLGLKQNLL DLLLSYNPLW LRIGLETIYG
EVLMIESNQD IIGLSTFIIS RFLSNPDIIK KYRDSSNLES FSNKKDFKEA LGQYVIKQFL
LLIFCIDQAK LTRLIDHDPC LFCMDAKFKS SRDLLLKLSR EYLRGEGDII RHLGQFGYNV
THVQTPLDEY NYAVTNLAVD LRDGVRLARL IELFSREWGI TSNLKLPVNS RLQKLKNVQE
SLAVLKEKKL LNNIEVKLYG SAIVDGHREK TLALLWKVIQ HYQVNVILNE DHLREEIIYL
RREYRKKLKL LSPDIDISYT IPYNDMYVDH LQLNLLLSWC QSVCKLYGIE INNFTASFGD
GRALCCLVHH YHPGLLPYSK IRHETTLTIL NYEEEPDDNM TNLVDTKEGW SAVFSPKTGK
ASKYDKLKAN EKYNFNLYNH KIQEMRGVPL LFKASQIING IPEEKVMIAH LSYLCSKLLE
IRQESRAAIC IQKAWRSYSD MKELIIQQNR ETAAIKLQGV IRGYLTRKDC RNRINKVVII
QSYWRGYVAR CLVEDLRQEQ LEAKQEYAAT VIESAFRGYI ARKHYCKLRE AIVKAQSIWR
GGRVRCELTR QYQAAQIIQR YYRNSLITKA VHEEYCRIKN KIILLQAVFR GWHDRCFVAK
FRAAICIQSH WRGYHTRRNF MRTKQEIVTV QSCVRRWFAQ RRLQQYTTAA ITIQSMYRRW
HVQQNLQQQR KAATIIQKSF RCYYVKQKYR QLQQSALVIQ QQYRAMRAMQ IQQYTYLIIR
GACITLQAAI KGYLVRKQYL LEKAAAIRIQ SHYRCYKQRQ DYIKLCDSTI ILQRRWRATC
LQRTAIDKYR VICQSILTIQ TYYRGWVTRK CYNTKLRSAL IIQSAYRRAV CQRLYLNKKF
AAIMIQSNIR RWISHRAYVQ KYHAIMVLQA FVKGWLKGQD VRRVCDFYAI RQSCIFIQSR
IRGYLARKEL IRKRNAVRCI ENCYLTYTCR CRYLNTQHSA ITIQRWWLSV KKGRACRQFY
LTLTQSSILI QSMWQMHIAR SHYIQMRAAA ILIQSHYRRY RQIKKYTDLK IAASIIQQRY
RAQIEMRKVR AAYSSNMQAS IVLQSAWRSY VVRRQYLQTK RAATLIQSYH RRYLACKSYN
TMKIAAVVIQ QRYRAQIEMR KVHTAYSTIM QASIILQSAW RSYVVRRQYL QMKRAATLIQ
SYQRRYLACK RYNTMKIAAV VIQQRYRAQV KMRNDEKDYL TTKASAIKIQ AAYRGYQQRK
SLAKKHNAAI KIQALWKMNI QRKMYLRQYH ACTILQSHVR ATLLTIKTRK RYLQILQSTI
LLQSMSYQKQ REAVIKIQRK WRATLLRNHL HRHFRQMIQA SLTIQKWTRR YLAMKQYNIL
KAVIKIQTTY RGHICRRQFN RERSAALKIQ SMIRMHKQRC TYMQRLNAIH VIQKCTKAYL
LGQQIRQNFN YKKMKNACTM IQTALRRHLA YKQYQHLRAT TIKMQAQFRG KTVKKRYDQL
REATITLQRR LRANWIARYE LLQYHFIRGA IITIQSKYRS YVVRKKYCQL KDSIIKVQAN
VRCYQERNRY LQLLNAAIMM QRRYRSKIIA QKLNHEYRKL RQSAILIQAV YRGHLYRRHL
AQHNAAAITI QSFYRGYQVR RNHGDLVNTV TKLQAMFRRK KAQIYYKQLL RACSMIQQRY
RAKLAMKNTV KDYLCKRVAI IRLQSAVRGM FSRREAQKIR STIKLQAHVR GMLQRQNYMK
LKQSAIFIQS KIRSLLVRKD YQRQLNAIIY IQRWYRARCL ANATRYSYLY TCGAIITIQA
TYRGYSVRKL VNKQREAAIQ IQSFYRCYFQ RRQYTQLRKN AILLQACVRR QQLQERYQQM
QKATIILQNY YRAYKVSRDQ RESYLYIRTA VIRLQSCWRG YRTRKQIAFE NAALTLQKRY
RMKLIGQSIR NNYLQLREAV ICIQAFYRGH QCRKWTTKLR ACRIIVAHQR GYMIRKRIAQ
QNQAARLIQT RWRLHNRYTQ ANRRIERAAT LIQATWRGYI VRLNQLKHNK ALEEARQRIK
QANEAVTEDK KLSNRTKSAL RWLLKPNIYM SKLHEALRNL DNPTKFSQVC SENLANSDAL
EIIFKLIKSL NHSVPSYDLN NAALDVLINV ANFPTCTQAV YEAENSISTI IHVIHGYINK
NNAICYKASH LLKILLESGD SKMKVDMLTK DVTSSKKLIK IFEKVTINGN GKHLHIYNIG
RKNSKIASSK HLTTSCLLLV KELLKAQSTF YSKSINHVMG ALSSDIHDL
//
