ID B3RWM4_TRIAD Unreviewed; 461 AA.
AC B3RWM4;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=PPM-type phosphatase domain-containing protein {ECO:0000259|PROSITE:PS51746};
DE Flags: Fragment;
GN ORFNames=TRIADDRAFT_13008 {ECO:0000313|EMBL:EDV24721.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV24721.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV24721.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV24721.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SIMILARITY: Belongs to the PP2C family.
CC {ECO:0000256|RuleBase:RU003465}.
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DR EMBL; DS985245; EDV24721.1; -; Genomic_DNA.
DR RefSeq; XP_002112611.1; XM_002112575.1.
DR AlphaFoldDB; B3RWM4; -.
DR EnsemblMetazoa; TriadT13008; TriadP13008; TriadG13008.
DR GeneID; 6754261; -.
DR KEGG; tad:TRIADDRAFT_13008; -.
DR CTD; 6754261; -.
DR eggNOG; KOG1323; Eukaryota.
DR HOGENOM; CLU_029072_2_0_1; -.
DR InParanoid; B3RWM4; -.
DR OMA; YKEHIEW; -.
DR OrthoDB; 1450097at2759; -.
DR PhylomeDB; B3RWM4; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0004741; F:[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR000222; PP2C_BS.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR13832:SF354; GM14138P; 1.
DR PANTHER; PTHR13832; PROTEIN PHOSPHATASE 2C; 1.
DR Pfam; PF00481; PP2C; 2.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS01032; PPM_1; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW ECO:0000256|RuleBase:RU003465};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022}.
FT DOMAIN 96..461
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDV24721.1"
FT NON_TER 461
FT /evidence="ECO:0000313|EMBL:EDV24721.1"
SQ SEQUENCE 461 AA; 52144 MW; 0FDFADE5901C266F CRC64;
SIVDIMGGKA SIPSQHNHLS SQSYDFAPAK FRYNRPEFLR LTEEDLQKSK DRTCREIISP
SYQLPRFTGF AECINSGKSH LNEDQAAVGI YMLRLQTSLK LQSLSNKNVM KLVYDTLYNY
DILAMKAYNT SLSRILPYQY FAIFDGHGGT EAAIYAANSL HLIIYQKLTE AHNFYATLPS
INSELSTVKL EALIIGAIEE AFRELDQQIG NERQSCSISG GCTAIMALYF EKHLYVANAG
DCRALIIKQG IMEQLSTDFN PITDRQRLQY LAYLQPELLH AYYNRLYFKQ RIRKTDVGKP
VVYKDMDMVG WGTKIASEED FELVPMIRGG GKQCRLLDII STTRGFGDFD LKCQEGGPYL
KPFLTSCPEV KSLALDQDSY GPDDILILGC DGLYESLSNE EIGKIVLDCL QKCGREDNFR
YAKAAKTLVE TCRGMYDGRH WMKNDVELAS QDDISAFIIP L
//
