ID B3RYM6_TRIAD Unreviewed; 611 AA.
AC B3RYM6;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
GN ORFNames=TRIADDRAFT_56610 {ECO:0000313|EMBL:EDV25067.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV25067.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV25067.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV25067.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS985245; EDV25067.1; -; Genomic_DNA.
DR RefSeq; XP_002112957.1; XM_002112921.1.
DR AlphaFoldDB; B3RYM6; -.
DR STRING; 10228.B3RYM6; -.
DR EnsemblMetazoa; TriadT56610; TriadP56610; TriadG56610.
DR GeneID; 6754170; -.
DR KEGG; tad:TRIADDRAFT_56610; -.
DR CTD; 6754170; -.
DR eggNOG; KOG1055; Eukaryota.
DR HOGENOM; CLU_005240_3_0_1; -.
DR InParanoid; B3RYM6; -.
DR OMA; NESWARN; -.
DR OrthoDB; 2970339at2759; -.
DR PhylomeDB; B3RYM6; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0038039; C:G protein-coupled receptor heterodimeric complex; IBA:GO_Central.
DR GO; GO:0004965; F:G protein-coupled GABA receptor activity; IBA:GO_Central.
DR GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IBA:GO_Central.
DR CDD; cd15047; 7tmC_GABA-B-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR002455; GPCR3_GABA-B.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR PANTHER; PTHR10519:SF20; GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR PRINTS; PR01177; GABAB1RECPTR.
DR PRINTS; PR01176; GABABRECEPTR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 281..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 475..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 500..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 329..524
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 611 AA; 69967 MW; BC16B2AA44ACC450 CRC64;
MAAIAEYFNW TKSIRDLTKR FAAKNITLLT AEGIVDDAKD VIKNLKNKDA RIMFVVSRPD
AISYVLCEAY KKQYYGPKYV WVFPGWYPKH WYMDYIAKDI NCSSNQIYQV IQNYLSVYQF
YPINNKTTIS GRSAAGFQEY FHKFRNISQN DYLKGYVYDS VWTLALALNQ TDQQLTLSGG
SLLDLKYQNN RKMRIISEML DKTNFVGITG QINFNGADRE SNAYIYQFLG NKSDNYTVQV
GIYQRKLDTI EWDPNQRVQW LGDRVPVSHV SIETETISIS IPALIAFTIL SGIGILFCIG
LIAFTLNYRH DSIIVFGIDS GVVPLITVPA FCTVKIWLLC IGFTFAFGAL FAKTWRIHKI
FTCKTRQSVV IKDWHLLTTV FQLLIIDVII LLCWTIIDPM QLKHLTITTQ INQDESSTIS
RQLQYYCSCN QIVVWMAIVF GYKFLLLLIG SFLAYETRNV TIPALNDTKF IGFSIYNVTL
LAAVGSIISF VVRASPTTLY VLHAILIFIC STTTLMFIFI PKIYQWKLDR KHAEGASTGI
IHSSVEPIGC SPGSNNSSIV MSRQEKKLNA ELLRTRLQES YKHYHELKRE IDAIRHQLAI
LDCEETLIPT M
//
