ID B3RYW3_TRIAD Unreviewed; 936 AA.
AC B3RYW3;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN ORFNames=TRIADDRAFT_57237 {ECO:0000313|EMBL:EDV23739.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV23739.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV23739.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV23739.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
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DR EMBL; DS985246; EDV23739.1; -; Genomic_DNA.
DR RefSeq; XP_002113265.1; XM_002113229.1.
DR AlphaFoldDB; B3RYW3; -.
DR STRING; 10228.B3RYW3; -.
DR EnsemblMetazoa; TriadT57237; TriadP57237; TriadG57237.
DR GeneID; 6754478; -.
DR KEGG; tad:TRIADDRAFT_57237; -.
DR CTD; 6754478; -.
DR eggNOG; KOG1061; Eukaryota.
DR HOGENOM; CLU_006320_1_0_1; -.
DR InParanoid; B3RYW3; -.
DR OMA; IQFNRNX; -.
DR OrthoDB; 648032at2759; -.
DR PhylomeDB; B3RYW3; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR Gene3D; 2.60.40.1150; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.310.10; TATA-Binding Protein; 1.
DR InterPro; IPR026739; AP_beta.
DR InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015151; B-adaptin_app_sub_C.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR013037; Clathrin_b-adaptin_app_Ig-like.
DR InterPro; IPR009028; Coatomer/calthrin_app_sub_C.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR PANTHER; PTHR11134:SF3; AP COMPLEX SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR Pfam; PF09066; B2-adapt-app_C; 1.
DR PIRSF; PIRSF002291; AP_complex_beta; 1.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SMART; SM01020; B2-adapt-app_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF55711; Subdomain of clathrin and coatomer appendage domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002291};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR002291};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002291}.
FT DOMAIN 709..816
FT /note="Clathrin adaptor alpha/beta/gamma-adaptin appendage
FT Ig-like subdomain"
FT /evidence="ECO:0000259|SMART:SM00809"
FT DOMAIN 825..935
FT /note="Beta-adaptin appendage C-terminal subdomain"
FT /evidence="ECO:0000259|SMART:SM01020"
FT REGION 581..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..622
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 936 AA; 103834 MW; AE534DE1B71A3E24 CRC64;
MKEKPFHHRG EIFELKAELN SDKKDKKKEA VKKVIASMTV GKDVSSLFPD VINCMQTENL
ELKKLVYLYL MNYAKTQPDM AILAVNTFVK DCEDPNPLIR ALAVRTMGCI RVDKITEYLC
EPLRKCLKDE DPYVRKTAAV CVAKLHDINS QLVEDQGFLE SLREILSDSN PMVVANAVAS
LSEIHKTSPN PTGVFDMNSG TVNKLLTALN ECTEWGQIFI LDAIAEYQPV SDREAQSIVE
RVTPRLSHAN AAVVLSAVKV LMQMMEIIKN DQIIDQLSRK LAPTLVTLLS SEPEIQYVSL
RNINLIVQKR PEILRNEIKA FFVKYNDPIY VKLEKLDIMI RLSTSSNIAQ VLAELKEYAT
EVDVDFVRKS VRAIGRCAIK VEQAAEKCVS TLIDLIQTKV NYVVQEAVVV IRDIFRKYPN
KYESIISTLC ENLDSLDEPD AKASMIWIVG EYAERIDNAD ELLQSFLDGF HDETTQVQLQ
LLTAIVKLFL KRPADTQDLV QSVLSLVTQE SDNPDLRDRG YIYWRLLSTD PAAAKEVVLA
EKPLIAEETD LLEPTLLDEL MCHISTLASV YHKPPSSFVE GNSPIRKLPI PRESTTSSDN
TDAAENQVQT QQQPAAAAPA QPTVISTPQE SAVAMDLLGD LASFDSTPST TANDMYAPNV
QPAGSSVIDL LSGTLDSLQM GGNTAGNQSG GLSSLSDMFS TGTSTFSEPK VVWLSAAQGK
GLEISGTFSL RQNVVHMDMT FTNNAMQAMG GFAIQFNKNS FGLVPAAQLE VRSPLPPRQS
ADSSLQLKPL GAILKMDPLN KLQIAIKNSI DVFYFDVLIP YHVLFVEDGK LESREFLTQW
KEIPNNSERS FDINNVPASS DAIENKLKMS NVFTVAKRNV DGQNMHYMSL KFTNNILVLA
ELKIQSGNPT LKLALKSSIA EVLPGVYQAF ELILHS
//
