ID B3RZG0_TRIAD Unreviewed; 213 AA.
AC B3RZG0;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
DE Flags: Fragment;
GN ORFNames=TRIADDRAFT_5635 {ECO:0000313|EMBL:EDV23836.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV23836.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV23836.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV23836.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; DS985246; EDV23836.1; -; Genomic_DNA.
DR RefSeq; XP_002113362.1; XM_002113326.1.
DR AlphaFoldDB; B3RZG0; -.
DR STRING; 10228.B3RZG0; -.
DR EnsemblMetazoa; TriadT5635; TriadP5635; TriadG5635.
DR GeneID; 6754936; -.
DR KEGG; tad:TRIADDRAFT_5635; -.
DR CTD; 6754936; -.
DR eggNOG; KOG1217; Eukaryota.
DR HOGENOM; CLU_004826_3_0_1; -.
DR InParanoid; B3RZG0; -.
DR OMA; ENAICIC; -.
DR OrthoDB; 5473534at2759; -.
DR PhylomeDB; B3RZG0; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IBA:GO_Central.
DR GO; GO:0010001; P:glial cell differentiation; IBA:GO_Central.
DR GO; GO:0002052; P:positive regulation of neuroblast proliferation; IBA:GO_Central.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.10.25.10; Laminin; 6.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR PANTHER; PTHR24049; CRUMBS FAMILY MEMBER; 1.
DR PANTHER; PTHR24049:SF22; DROSOPHILA CRUMBS HOMOLOG; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF12661; hEGF; 1.
DR SMART; SM00181; EGF; 5.
DR SMART; SM00179; EGF_CA; 3.
DR SUPFAM; SSF57196; EGF/Laminin; 6.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 5.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000009022}.
FT DOMAIN 1..26
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 29..66
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 69..105
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 106..144
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 147..183
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 187..213
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 16..25
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 33..43
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 56..65
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 73..83
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 95..104
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 115..132
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 134..143
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 173..182
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDV23836.1"
FT NON_TER 213
FT /evidence="ECO:0000313|EMBL:EDV23836.1"
SQ SEQUENCE 213 AA; 22805 MW; 232F495B67F2EE37 CRC64;
GLCFNSSNGQ SYTCDCFTGF QGVNCEQVML NPCASNPCFA GQCTYSNRTL AYQCNCNSGW
SGQYCDIGIT DGCQDQPCWA GTCQPTGDQN FTCNCVPGYT GKLCDQILPC YVNPCQHDGT
CTNTNAGTNY TCTCQGRFTG RNCDTIINDF CSDNPCGNRG ICLDIGDRHQ CVCNPGYKGS
NCQVNESHSP CFSSPCKNGG SCQNEADGYS CSC
//
