ID B3S3J3_TRIAD Unreviewed; 240 AA.
AC B3S3J3;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Thiopurine S-methyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=TRIADDRAFT_58744 {ECO:0000313|EMBL:EDV22805.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV22805.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV22805.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV22805.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; DS985248; EDV22805.1; -; Genomic_DNA.
DR RefSeq; XP_002114671.1; XM_002114635.1.
DR AlphaFoldDB; B3S3J3; -.
DR STRING; 10228.B3S3J3; -.
DR EnsemblMetazoa; TriadT58744; TriadP58744; TriadG58744.
DR GeneID; 6755884; -.
DR KEGG; tad:TRIADDRAFT_58744; -.
DR CTD; 6755884; -.
DR eggNOG; ENOG502QSF5; Eukaryota.
DR HOGENOM; CLU_085515_0_0_1; -.
DR InParanoid; B3S3J3; -.
DR OMA; LWCGDFF; -.
DR OrthoDB; 2902171at2759; -.
DR PhylomeDB; B3S3J3; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008119; F:thiopurine S-methyltransferase activity; IBA:GO_Central.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR008854; TPMT.
DR PANTHER; PTHR10259; THIOPURINE S-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10259:SF11; THIOPURINE S-METHYLTRANSFERASE; 1.
DR Pfam; PF05724; TPMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51585; SAM_MT_TPMT; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 240 AA; 27715 MW; F46375534811FB3D CRC64;
MGLTYEDYIV LGNTNAEDWA NYWAEGDTTW VSDKCNPYLI KYYQSYLACD QPSTIFVPLC
GKTQDMLWLA RNGNRVIGVE MVPQPCIDFF NENNIEYHVE KLQGMGNSKV YRSQAEGLDI
TIYNCDFYEL TAELLGCQCD RFWDRAAFFA INPDQHPKYI KQLMSLLTPD AQGILFTVEY
DIDQRPDVSS PFCIPESRLS EILSPIASVK FLELISMPRS WYGHLSLNSM DGKFYYLKLK
//
