ID B3S662_TRIAD Unreviewed; 455 AA.
AC B3S662;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=Amino acid permease/ SLC12A domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TRIADDRAFT_59688 {ECO:0000313|EMBL:EDV21701.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV21701.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV21701.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV21701.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS985252; EDV21701.1; -; Genomic_DNA.
DR RefSeq; XP_002115849.1; XM_002115813.1.
DR AlphaFoldDB; B3S662; -.
DR STRING; 10228.B3S662; -.
DR EnsemblMetazoa; TriadT59688; TriadP59688; TriadG59688.
DR GeneID; 6756929; -.
DR KEGG; tad:TRIADDRAFT_59688; -.
DR CTD; 6756929; -.
DR eggNOG; KOG1288; Eukaryota.
DR HOGENOM; CLU_601775_0_0_1; -.
DR InParanoid; B3S662; -.
DR OrthoDB; 5490251at2759; -.
DR PhylomeDB; B3S662; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004842; SLC12A_fam.
DR PANTHER; PTHR11827:SF72; GH08340P; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 455 AA; 49773 MW; FCD2AAE844F15E9E CRC64;
MSGMPTEVQP LLSPCHSNVN DGNYREGKLS TFLGVVVPCI LSIFSVILFL RLGFVVGQAG
FLTVIGMLVL AYGLCIKFTA IPGSTWWQYL YGSLVLLFCL IVCVFGAGIF AKTSLIIFLA
VMVAISSSVV SFIAQKAFAV NNQSILNENE TVLNFAYTGW DIETFRKNLY SNYTEDITTG
IKQDFQSVFA VLFNGCTGIM VTFTSFTCSR GLLLNNYNYI QAINLCPPLI TIGVFAATLS
AALSTLIGAS RILEAVARDD ILDLIPQIII IAKELNAIAP IVTMFYLLSY GATNFACFLL
RVASAPNFST LLDIYVTIIE RVALTNEKHR SQFLGWLSFA DKRHLKAFVE ITTANCVRDG
ARNLMLDSQQ LSSHDYVGII KDAIMMQKNV LIVVTFNSKL SPSIHANSHG SDCIQCVNPT
PSQVNRLIRT HSSNAKNLPP IVMAHGTKTV TCTSV
//
