ID B3SBM4_TRIAD Unreviewed; 255 AA.
AC B3SBM4;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
GN ORFNames=TRIADDRAFT_61667 {ECO:0000313|EMBL:EDV19887.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV19887.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV19887.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV19887.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC {ECO:0000256|ARBA:ARBA00006840, ECO:0000256|RuleBase:RU361218}.
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DR EMBL; DS985265; EDV19887.1; -; Genomic_DNA.
DR RefSeq; XP_002117629.1; XM_002117593.1.
DR AlphaFoldDB; B3SBM4; -.
DR EnsemblMetazoa; TriadT61667; TriadP61667; TriadG61667.
DR GeneID; 6758842; -.
DR KEGG; tad:TRIADDRAFT_61667; -.
DR CTD; 6758842; -.
DR eggNOG; KOG3882; Eukaryota.
DR HOGENOM; CLU_055524_4_2_1; -.
DR InParanoid; B3SBM4; -.
DR OMA; PANHYNE; -.
DR OrthoDB; 2913577at2759; -.
DR PhylomeDB; B3SBM4; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR000301; Tetraspanin_animals.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282; TETRASPANIN; 1.
DR PANTHER; PTHR19282:SF456; TETRASPANIN; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PIRSF; PIRSF002419; Tetraspanin; 1.
DR PRINTS; PR00259; TMFOUR.
DR SUPFAM; SSF48652; Tetraspanin; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361218};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Transmembrane {ECO:0000256|RuleBase:RU361218};
KW Transmembrane helix {ECO:0000256|RuleBase:RU361218}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 53..74
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 81..104
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 219..244
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
SQ SEQUENCE 255 AA; 27810 MW; 6F40BC023ACB085E CRC64;
MGCGERCMLI SFYIITFGFM VLGAALLGLG IYIRTNGNGL DIVVDTSWHT AAYIMIAIGV
MVFLISLLGC LGAVRKSTCL LGTYLSCMIA IFIVELAGAI YAGINRTAVE STIRNKFSTE
VKDSYGQPQK NAITTGIDQI QTLFQCCGID SPFNWTNSKW SNSKPVGNYG PPVPDSCCKM
EMPNCGTNPA NHYNETIFTE AIYQQGCYIK IRDLISNNIA IAIAILATFG CLQIVGLLIA
RLLYSTLGYE YGYEI
//
