ID B3SCB0_TRIAD Unreviewed; 311 AA.
AC B3SCB0;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=G-protein coupled receptors family 2 profile 2 domain-containing protein {ECO:0000259|PROSITE:PS50261};
GN ORFNames=TRIADDRAFT_61907 {ECO:0000313|EMBL:EDV19647.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV19647.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV19647.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV19647.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS985269; EDV19647.1; -; Genomic_DNA.
DR RefSeq; XP_002117885.1; XM_002117849.1.
DR AlphaFoldDB; B3SCB0; -.
DR EnsemblMetazoa; TriadT61907; TriadP61907; TriadG61907.
DR GeneID; 6759082; -.
DR KEGG; tad:TRIADDRAFT_61907; -.
DR CTD; 6759082; -.
DR eggNOG; KOG4193; Eukaryota.
DR HOGENOM; CLU_895249_0_0_1; -.
DR InParanoid; B3SCB0; -.
DR OrthoDB; 5345963at2759; -.
DR PhylomeDB; B3SCB0; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd13952; 7tm_classB; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR12011:SF470; LATROPHILIN-LIKE PROTEIN LAT-2; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..208
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 271..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 311 AA; 35288 MW; 081CD65759D3CB27 CRC64;
MILLHVAFQN VAFCGSIIFI GHYLAIAVFM WMLLEGVQIL LTFISVFSAN SDQCGKRLSI
MIVFGWGCPA VISSSCVLTN NNTYIFKFEE YEYALCWFDT TNSWLLYGPV VAITGINFVI
AIVVLIILEK NRNPRLLTKA KDDSGDIRQR IRSFLVLCPL LGIPWLITVI SWFVQCQNAT
LYIILLLLSI TINSLQGVFF FLAHCILNRK VRDAIRKRFF RYKSKRSTST SRTLPTSPET
LRRHLSRIKR ETLIKYETKF ESIDGLTRTP STGSNFIART HSSGNSQNSN HAKPLDEKKS
PTSITIITTA I
//
