ID B3SFP7_TRIAD Unreviewed; 173 AA.
AC B3SFP7;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
GN ORFNames=TRIADDRAFT_35120 {ECO:0000313|EMBL:EDV18448.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV18448.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV18448.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV18448.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; DS986522; EDV18448.1; -; Genomic_DNA.
DR RefSeq; XP_002119066.1; XM_002119030.1.
DR AlphaFoldDB; B3SFP7; -.
DR STRING; 10228.B3SFP7; -.
DR EnsemblMetazoa; TriadT35120; TriadP35120; TriadG35120.
DR GeneID; 6760280; -.
DR KEGG; tad:TRIADDRAFT_35120; -.
DR CTD; 6760280; -.
DR eggNOG; KOG1217; Eukaryota.
DR HOGENOM; CLU_004826_3_4_1; -.
DR InParanoid; B3SFP7; -.
DR OMA; PGFERIC; -.
DR OrthoDB; 5400566at2759; -.
DR PhylomeDB; B3SFP7; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IBA:GO_Central.
DR GO; GO:0010001; P:glial cell differentiation; IBA:GO_Central.
DR GO; GO:0002052; P:positive regulation of neuroblast proliferation; IBA:GO_Central.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00054; EGF_CA; 4.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR24049; CRUMBS FAMILY MEMBER; 1.
DR PANTHER; PTHR24049:SF30; DELTA-LIKE PROTEIN; 1.
DR Pfam; PF00008; EGF; 4.
DR PRINTS; PR00010; EGFBLOOD.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 4.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 4.
DR PROSITE; PS00022; EGF_1; 5.
DR PROSITE; PS01186; EGF_2; 5.
DR PROSITE; PS50026; EGF_3; 5.
DR PROSITE; PS01187; EGF_CA; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..18
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 20..56
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 58..94
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 96..132
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 134..170
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 8..17
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 46..55
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 84..93
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 122..131
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 160..169
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDV18448.1"
SQ SEQUENCE 173 AA; 18214 MW; 9944FD52FB52F481 CRC64;
IDRYSCQCSG GYQGINCEFE IDECLSNPCL NDGTCIDSNN GYTCSCKAGF SGALCQLEID
ECLSNPCLND GTCIDSNNAY TCSCRAGFSG ILCQSEIDEC LSNPCLNDGT CIDSNNGYTC
SCKAGFSGAL CQLEIDECLS NPCLNDGTCI DSNNAYTCSC RAGFSGILCQ SGK
//
