ID B4D3L8_9BACT Unreviewed; 403 AA.
AC B4D3L8;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
DE Flags: Precursor;
GN ORFNames=CfE428DRAFT_3506 {ECO:0000313|EMBL:EDY18848.1};
OS Chthoniobacter flavus Ellin428.
OC Bacteria; Verrucomicrobiota; Spartobacteria; Chthoniobacterales;
OC Chthoniobacteraceae; Chthoniobacter.
OX NCBI_TaxID=497964 {ECO:0000313|EMBL:EDY18848.1, ECO:0000313|Proteomes:UP000005824};
RN [1] {ECO:0000313|EMBL:EDY18848.1, ECO:0000313|Proteomes:UP000005824}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ellin428 {ECO:0000313|EMBL:EDY18848.1,
RC ECO:0000313|Proteomes:UP000005824};
RX PubMed=21460085; DOI=10.1128/JB.00295-11;
RA Kant R., van Passel M.W., Palva A., Lucas S., Lapidus A.,
RA Glavina Del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S.,
RA Larimer F.W., Land M.L., Hauser L., Sangwan P., de Vos W.M., Janssen P.H.,
RA Smidt H.;
RT "Genome sequence of Chthoniobacter flavus Ellin428, an aerobic
RT heterotrophic soil bacterium.";
RL J. Bacteriol. 193:2902-2903(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDY18848.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ABVL01000010; EDY18848.1; -; Genomic_DNA.
DR RefSeq; WP_006980831.1; NZ_ABVL01000010.1.
DR AlphaFoldDB; B4D3L8; -.
DR STRING; 497964.CfE428DRAFT_3506; -.
DR GeneID; 78182592; -.
DR eggNOG; COG4409; Bacteria.
DR InParanoid; B4D3L8; -.
DR Proteomes; UP000005824; Unassembled WGS sequence.
DR GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000313|EMBL:EDY18848.1};
KW Hydrolase {ECO:0000313|EMBL:EDY18848.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005824};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..403
FT /note="exo-alpha-sialidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002802721"
FT DOMAIN 113..368
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13088"
SQ SEQUENCE 403 AA; 44411 MW; 3415F9E3641A7889 CRC64;
MRSLLCCLLA ALSLSTVSAA EPFLEKSDLF TAGDGGYKLF HIPGIVVTAK GTVLAWCEAR
KKGGDWDQIE IVLKRSTDEG KTWSDFKSIA NVPGPKTKNP ASLKVKGVDP NDVTYNNPVL
IADRDGTVHM LFCLEYMRCF YQRSTDDGQT WSTPVEITSA FEGFRPAYAW KVLATGPDHG
IQLRNGRLVV PVWLSLATGN NGHHPSVTAT IYSDDQGKTW HHGEIAVPNT EEWINPNETI
AIELADGSVM LNVRSESKAH RRLATISKDG ATNWSTPKFD DALLEPICMA SMVRYSLARN
GGKNRILFCN PDNVSREDGK GVAGRFRDRK NLTVQLSYDE GKTWPVKRAV EPGASMYSDI
AVAKDGTILC LYDRGTKVGF AGEYITLARF NLEWLTEGKE SAK
//
