ID B4DCE8_9BACT Unreviewed; 349 AA.
AC B4DCE8;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Cobalamin B12-binding domain protein {ECO:0000313|EMBL:EDY15897.1};
GN ORFNames=CfE428DRAFT_6589 {ECO:0000313|EMBL:EDY15897.1};
OS Chthoniobacter flavus Ellin428.
OC Bacteria; Verrucomicrobiota; Spartobacteria; Chthoniobacterales;
OC Chthoniobacteraceae; Chthoniobacter.
OX NCBI_TaxID=497964 {ECO:0000313|EMBL:EDY15897.1, ECO:0000313|Proteomes:UP000005824};
RN [1] {ECO:0000313|EMBL:EDY15897.1, ECO:0000313|Proteomes:UP000005824}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ellin428 {ECO:0000313|EMBL:EDY15897.1,
RC ECO:0000313|Proteomes:UP000005824};
RX PubMed=21460085; DOI=10.1128/JB.00295-11;
RA Kant R., van Passel M.W., Palva A., Lucas S., Lapidus A.,
RA Glavina Del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S.,
RA Larimer F.W., Land M.L., Hauser L., Sangwan P., de Vos W.M., Janssen P.H.,
RA Smidt H.;
RT "Genome sequence of Chthoniobacter flavus Ellin428, an aerobic
RT heterotrophic soil bacterium.";
RL J. Bacteriol. 193:2902-2903(2011).
CC -!- COFACTOR:
CC Name=adenosylcob(III)alamin; Xref=ChEBI:CHEBI:18408;
CC Evidence={ECO:0000256|ARBA:ARBA00001922};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDY15897.1}.
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DR EMBL; ABVL01000048; EDY15897.1; -; Genomic_DNA.
DR RefSeq; WP_006983906.1; NZ_ABVL01000048.1.
DR AlphaFoldDB; B4DCE8; -.
DR STRING; 497964.CfE428DRAFT_6589; -.
DR GeneID; 78185985; -.
DR eggNOG; COG1703; Bacteria.
DR eggNOG; COG2185; Bacteria.
DR InParanoid; B4DCE8; -.
DR Proteomes; UP000005824; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0016853; F:isomerase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006159; Acid_CoA_mut_C.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00640; acid_CoA_mut_C; 1.
DR PANTHER; PTHR43087:SF1; LAO_AO TRANSPORT SYSTEM ATPASE; 1.
DR PANTHER; PTHR43087; LYSINE/ARGININE/ORNITHINE TRANSPORT SYSTEM KINASE; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF03308; MeaB; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000005824}.
FT DOMAIN 4..134
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 349 AA; 37760 MW; D00769E06BDFE78F CRC64;
MAASVRLLTA VPICDGHDSA ISTINLEFIH HGIEVVYLGY HRSARDIVRA AIQEGVDAIG
ISSYNGGHVE FFAEVVALLK KQRAAKIGVF GGGGGTITKA DATIMQRKGV DRIFFAGTPM
EEMIRFAREA YGGRRRRSVK LPRFSAGKRK TMAPCIGITG PGGAGKTTLI DELVLRWLKV
QPDARIAILS HDPSIVGKGA LLGDRATMIY SQDDRVFMRS LATRGRAGGL SPETAQWVRT
MKHGGFDVVF VETVGIGQEA MPFRSKLVDK SIFVMSADYG SQLQLQKIAM LDVADIVVVN
KGDLAGAPTA VAEVGRRIER GRSGQRVIAT VAKRHRDPGV DCLFEELRS
//
