ID B4E620_BURCJ Unreviewed; 378 AA.
AC B4E620;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Thiamine biosynthesis oxidoreductase ThiO {ECO:0000313|EMBL:CAR50607.1};
GN Name=thiO {ECO:0000313|EMBL:CAR50607.1};
GN ORFNames=BCAL0297 {ECO:0000313|EMBL:CAR50607.1};
OS Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 /
OS NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=216591 {ECO:0000313|EMBL:CAR50607.1, ECO:0000313|Proteomes:UP000001035};
RN [1] {ECO:0000313|EMBL:CAR50607.1, ECO:0000313|Proteomes:UP000001035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 /
RC CF5610 {ECO:0000313|Proteomes:UP000001035};
RX PubMed=18931103; DOI=10.1128/JB.01230-08;
RA Holden M.T., Seth-Smith H.M., Crossman L.C., Sebaihia M., Bentley S.D.,
RA Cerdeno-Tarraga A.M., Thomson N.R., Bason N., Quail M.A., Sharp S.,
RA Cherevach I., Churcher C., Goodhead I., Hauser H., Holroyd N., Mungall K.,
RA Scott P., Walker D., White B., Rose H., Iversen P., Mil-Homens D.,
RA Rocha E.P., Fialho A.M., Baldwin A., Dowson C., Barrell B.G., Govan J.R.,
RA Vandamme P., Hart C.A., Mahenthiralingam E., Parkhill J.;
RT "The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of
RT cystic fibrosis patients.";
RL J. Bacteriol. 191:261-277(2009).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM747720; CAR50607.1; -; Genomic_DNA.
DR RefSeq; WP_006488532.1; NC_011000.1.
DR AlphaFoldDB; B4E620; -.
DR GeneID; 56556847; -.
DR KEGG; bcj:BCAL0297; -.
DR eggNOG; COG0665; Bacteria.
DR HOGENOM; CLU_007884_1_0_4; -.
DR BioCyc; BCEN216591:G1G1V-342-MONOMER; -.
DR Proteomes; UP000001035; Chromosome 1.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR13847:SF293; TRNA 5-METHYLAMINOMETHYL-2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC; 1.
DR Pfam; PF01266; DAO; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
FT DOMAIN 9..337
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
SQ SEQUENCE 378 AA; 40314 MW; 0CE28C6F8338D725 CRC64;
MNVRDARPDF AVLGGGLVGR LIAWRLAGDG HRVALYERGG PDGEQSAAWI AAAMLAPLAE
AASAELLITE LGAASLARWP QWLAELPEPV FFQHRGTLVV WHHADRAEAP LFERRVRANA
PAELFDGGFV TLAGAQVDAA EPALAGRFAR GLMLPREGQL DNRQALRALA AGLAERGVAL
HWHAAVDDAN LPAAHVTIDC RGLGAKPALP ALRGIRGEVA RVHAPGIGLT RPVRLLHPRY
PLYIAPKQDD LYVIGATEVE GEDMSPVSVR SALELLSAAF SVHPAFGEAR ILELNAQCRP
TLPDHRPAVI WDGASTLAVN GLYRHGFMIA PEVAQAAVAC AQAALGGTLG DPDAFAAWRA
TARWPTLLHH RNDAHQPA
//
