ID B4E8D5_BURCJ Unreviewed; 759 AA.
AC B4E8D5;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Ornithine decarboxylase {ECO:0000313|EMBL:CAR52943.1};
GN ORFNames=BCAL2641 {ECO:0000313|EMBL:CAR52943.1};
OS Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 /
OS NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=216591 {ECO:0000313|EMBL:CAR52943.1, ECO:0000313|Proteomes:UP000001035};
RN [1] {ECO:0000313|EMBL:CAR52943.1, ECO:0000313|Proteomes:UP000001035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 /
RC CF5610 {ECO:0000313|Proteomes:UP000001035};
RX PubMed=18931103; DOI=10.1128/JB.01230-08;
RA Holden M.T., Seth-Smith H.M., Crossman L.C., Sebaihia M., Bentley S.D.,
RA Cerdeno-Tarraga A.M., Thomson N.R., Bason N., Quail M.A., Sharp S.,
RA Cherevach I., Churcher C., Goodhead I., Hauser H., Holroyd N., Mungall K.,
RA Scott P., Walker D., White B., Rose H., Iversen P., Mil-Homens D.,
RA Rocha E.P., Fialho A.M., Baldwin A., Dowson C., Barrell B.G., Govan J.R.,
RA Vandamme P., Hart C.A., Mahenthiralingam E., Parkhill J.;
RT "The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of
RT cystic fibrosis patients.";
RL J. Bacteriol. 191:261-277(2009).
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC {ECO:0000256|ARBA:ARBA00010671}.
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DR EMBL; AM747720; CAR52943.1; -; Genomic_DNA.
DR RefSeq; WP_006491304.1; NC_011000.1.
DR AlphaFoldDB; B4E8D5; -.
DR KEGG; bcj:BCAL2641; -.
DR eggNOG; COG1982; Bacteria.
DR HOGENOM; CLU_014292_3_0_4; -.
DR BioCyc; BCEN216591:G1G1V-2928-MONOMER; -.
DR Proteomes; UP000001035; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016831; F:carboxy-lyase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR005308; OKR_de-COase_N.
DR InterPro; IPR011193; Orn/lys/arg_de-COase.
DR InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR45229:SF3; BIODEGRADATIVE ARGININE DECARBOXYLASE; 1.
DR PANTHER; PTHR45229; CONSTITUTIVE ORNITHINE DECARBOXYLASE; 1.
DR Pfam; PF01276; OKR_DC_1; 1.
DR Pfam; PF03711; OKR_DC_1_C; 1.
DR Pfam; PF03709; OKR_DC_1_N; 1.
DR PIRSF; PIRSF009393; Orn_decarb; 1.
DR SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00703; OKR_DC_1; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR009393-1}.
FT DOMAIN 401..415
FT /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT attachment site"
FT /evidence="ECO:0000259|PROSITE:PS00703"
FT MOD_RES 406
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR009393-1"
SQ SEQUENCE 759 AA; 85578 MW; 77D039BD8ABDD68F CRC64;
MKFRFPVVII DEDFRSENIS GSGIRALAEA IEKEGVEVLG LTSYGDLTSF AQQSSRASCF
ILSIDDDELM LGEIGPDGEL PELATAIIEL RAFVTEVRRR NADIPIFLYG ETRTSRHLPN
DILRELHGFI HMFEDTPEFV ARHIIREAKV YLDSLAPPFF KELVKYADEG SYSWHCPGHS
GGVAFLKNPL GQMFHQFFGE NMLRADVCNA VDELGQLLDH TGPVAASERN AARIFSADHL
FFVTNGTSTS NKIVWHATVA PGDIVLVDRN CHKSILHAIT MTGAIPVFLT PTRNHFGIIG
PIPRDEFKPE NIRKKIEANP FAREALRENP DMKPRILTIT QSTYDGVVYN VEMIKDLLGD
LLDTLHFDEA WLPHATFHDF YRDMHAIGDG RPRTGALVFA THSTHKLLAG ISQASQIVVQ
DSENRTFDKH RFNEAYLMHT STSPQYAIIA SCDVAAAMME PPGGTALVEE SIAEAIDFRR
AMRKVDAEYG DDWFFSVWGP DNLSEEGIGS REDWMLKPND HWHGFGPLAE GFNMLDPIKA
TIITPGLDVD GEFGETGIPA AIVTKYLAEH GIIVEKTGLY SFFIMFTIGI TKGRWNSMVT
ELQQFKDDYD NNQPLWRVLP EFVAQHPRYE RVGLRDLCTQ IHDVYRANDI ARLTTEMYLS
DMEPAMKPSD AFAKLAHRKI DRVPLDELEG RVTSILLTPY PPGIPLLIPG ERFNKTIVNY
LRFARDFNER FPGFHTDIHG LVAEEVNGRV EYFVDCVRD
//
