ID B4EKS4_BURCJ Unreviewed; 477 AA.
AC B4EKS4;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=GntR family regulatory protein {ECO:0000313|EMBL:CAR55531.1};
GN ORFNames=BCAM1674 {ECO:0000313|EMBL:CAR55531.1};
OS Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 /
OS NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=216591 {ECO:0000313|EMBL:CAR55531.1, ECO:0000313|Proteomes:UP000001035};
RN [1] {ECO:0000313|EMBL:CAR55531.1, ECO:0000313|Proteomes:UP000001035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 /
RC CF5610 {ECO:0000313|Proteomes:UP000001035};
RX PubMed=18931103; DOI=10.1128/JB.01230-08;
RA Holden M.T., Seth-Smith H.M., Crossman L.C., Sebaihia M., Bentley S.D.,
RA Cerdeno-Tarraga A.M., Thomson N.R., Bason N., Quail M.A., Sharp S.,
RA Cherevach I., Churcher C., Goodhead I., Hauser H., Holroyd N., Mungall K.,
RA Scott P., Walker D., White B., Rose H., Iversen P., Mil-Homens D.,
RA Rocha E.P., Fialho A.M., Baldwin A., Dowson C., Barrell B.G., Govan J.R.,
RA Vandamme P., Hart C.A., Mahenthiralingam E., Parkhill J.;
RT "The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of
RT cystic fibrosis patients.";
RL J. Bacteriol. 191:261-277(2009).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM747721; CAR55531.1; -; Genomic_DNA.
DR RefSeq; WP_006486002.1; NC_011001.1.
DR AlphaFoldDB; B4EKS4; -.
DR KEGG; bcj:BCAM1674; -.
DR eggNOG; COG1167; Bacteria.
DR HOGENOM; CLU_017584_0_0_4; -.
DR BioCyc; BCEN216591:G1G1V-5705-MONOMER; -.
DR Proteomes; UP000001035; Chromosome 2.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR42790; AMINOTRANSFERASE; 1.
DR PANTHER; PTHR42790:SF9; GNTR FAMILY REGULATORY PROTEIN-RELATED; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..69
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 477 AA; 52542 MW; C8EADA20DB9D28A3 CRC64;
MKRYETLAHT IADDIRNGNL AVGTRLPSLR QIIAQHGVSQ STVFRAYYLL EQWGLIRARE
RSGYYVAPGA QPAASPATKR RTRRTDATRK VDISNLVFSV LDAATQPGIV PLGSAFPAPQ
LFPLPRLAKS LAQATRLVSP WSTVVDLPPG NEALRQQIVR RYLATGISQP IDELVVTNGA
LEALNLCLMA VTRPGDVVAV EAPGFYAALQ AIERLDLRAV EIPVDPRTGL DLAALANALD
RHDIRACWFM TNFQNPTGVT LTVDKKRALV ELLAARNVPL IEDDVYGELH FGPDYPLPAR
AFDRHGLVMH CSSFSKTLAP GYRIGWAAAG RFAEKVQRLK LMTTLSASIP AQAGIANYLE
HGGYDRHLRV LRGALHAQLD RMDDALRRWL PADVEWVRPE GGYFLWLAFP DAIDAMALHR
EAIARGISFA PGPLFSAAHG FERCVRVNFG HPWSRDIERA IRVLGELVAQ PSVRKAG
//
