ID B4EMA4_BURCJ Unreviewed; 414 AA.
AC B4EMA4;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Pyridine nucleotide-disulphide oxidoreductase {ECO:0000313|EMBL:CAR55700.1};
GN ORFNames=BCAM1842 {ECO:0000313|EMBL:CAR55700.1};
OS Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 /
OS NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=216591 {ECO:0000313|EMBL:CAR55700.1, ECO:0000313|Proteomes:UP000001035};
RN [1] {ECO:0000313|EMBL:CAR55700.1, ECO:0000313|Proteomes:UP000001035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 /
RC CF5610 {ECO:0000313|Proteomes:UP000001035};
RX PubMed=18931103; DOI=10.1128/JB.01230-08;
RA Holden M.T., Seth-Smith H.M., Crossman L.C., Sebaihia M., Bentley S.D.,
RA Cerdeno-Tarraga A.M., Thomson N.R., Bason N., Quail M.A., Sharp S.,
RA Cherevach I., Churcher C., Goodhead I., Hauser H., Holroyd N., Mungall K.,
RA Scott P., Walker D., White B., Rose H., Iversen P., Mil-Homens D.,
RA Rocha E.P., Fialho A.M., Baldwin A., Dowson C., Barrell B.G., Govan J.R.,
RA Vandamme P., Hart C.A., Mahenthiralingam E., Parkhill J.;
RT "The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of
RT cystic fibrosis patients.";
RL J. Bacteriol. 191:261-277(2009).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; AM747721; CAR55700.1; -; Genomic_DNA.
DR RefSeq; WP_006487198.1; NC_011001.1.
DR AlphaFoldDB; B4EMA4; -.
DR KEGG; bcj:BCAM1842; -.
DR eggNOG; COG0446; Bacteria.
DR HOGENOM; CLU_003291_4_0_4; -.
DR BioCyc; BCEN216591:G1G1V-5886-MONOMER; -.
DR Proteomes; UP000001035; Chromosome 2.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.30.390.30; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR InterPro; IPR028202; Reductase_C.
DR PANTHER; PTHR43557; APOPTOSIS-INDUCING FACTOR 1; 1.
DR PANTHER; PTHR43557:SF2; RIESKE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF14759; Reductase_C; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
PE 4: Predicted;
FT DOMAIN 14..314
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 333..413
FT /note="Reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14759"
SQ SEQUENCE 414 AA; 44116 MW; F9B31584832C81AB CRC64;
MSETNAREAA APATVVVIGG GQAAGWVLKT LRAEGYAGRL VMIADEPHLP YERPPLSKAV
LAGDADIETV RVVRPDEFDA LNVEAWQPER AASIDRARRV VKTESGREIE YDRLVIATGG
TSRRLPDALV NTPNLHYLRT LDEAAALGEK LRASRRVLVI GGGWIGLEVA ATARKLGVEA
VVVEGAPRLC GRSVPQIVSD FLLDLHRSNG VDVRTGAALA SLDPRPDDAS KVRATLADGT
TIDADFAVAG IGLALNASLA SDAGLAVDDG IVVDEYGATS DPAIFACGDV ANHHNGWLKR
RVRLESWANA QNQAIAAAKA VLGVRAPYAE IPWFWSDQYD VNLQILGDLP ADAQLVVRGD
LAARRATLFF VGDGHVRGVI AVNNARELKL ARKWMNQGRA VDTEALADTT QALA
//
