ID B4EV25_PROMH Unreviewed; 293 AA.
AC B4EV25;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=Magnesium and cobalt efflux protein CorC {ECO:0000256|ARBA:ARBA00040729};
GN Name=corC {ECO:0000313|EMBL:CAR41100.1};
GN OrderedLocusNames=PMI0444 {ECO:0000313|EMBL:CAR41100.1};
OS Proteus mirabilis (strain HI4320).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Proteus.
OX NCBI_TaxID=529507 {ECO:0000313|EMBL:CAR41100.1, ECO:0000313|Proteomes:UP000008319};
RN [1] {ECO:0000313|EMBL:CAR41100.1, ECO:0000313|Proteomes:UP000008319}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HI4320 {ECO:0000313|EMBL:CAR41100.1,
RC ECO:0000313|Proteomes:UP000008319};
RX PubMed=18375554; DOI=10.1128/JB.01981-07;
RA Pearson M.M., Sebaihia M., Churcher C., Quail M.A., Seshasayee A.S.,
RA Luscombe N.M., Abdellah Z., Arrosmith C., Atkin B., Chillingworth T.,
RA Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H.,
RA Rabbinowitsch E., Walker D., Whithead S., Thomson N.R., Rather P.N.,
RA Parkhill J., Mobley H.L.;
RT "Complete genome sequence of uropathogenic Proteus mirabilis, a master of
RT both adherence and motility.";
RL J. Bacteriol. 190:4027-4037(2008).
CC -!- FUNCTION: Plays a role in the transport of magnesium and cobalt ions.
CC {ECO:0000256|ARBA:ARBA00037273}.
CC -!- SIMILARITY: Belongs to the UPF0053 family.
CC {ECO:0000256|ARBA:ARBA00006337}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM942759; CAR41100.1; -; Genomic_DNA.
DR RefSeq; WP_004246033.1; NC_010554.1.
DR AlphaFoldDB; B4EV25; -.
DR EnsemblBacteria; CAR41100; CAR41100; PMI0444.
DR GeneID; 6801804; -.
DR KEGG; pmr:PMI0444; -.
DR eggNOG; COG4535; Bacteria.
DR HOGENOM; CLU_015237_3_0_6; -.
DR Proteomes; UP000008319; Chromosome.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF27; MAGNESIUM AND COBALT EFFLUX PROTEIN CORC; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM00116; CBS; 2.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703}; Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 72..132
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 137..194
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 293 AA; 33267 MW; BDADD07EAB46AD6A CRC64;
MSDDQSSSND NPGPKKGFLT LLNQLFHGEP KNRDDLMELI RDSEQKELID PDTRDMLEGV
MDIAEQRVRD IMIPRSQIVT LKRNQTLDEC LDVIIDSAHS RFPVISEDKD HIEGLLMAKD
LLPFMRTGAE PFSIDKVLRS AVVVPESKRV DRLLKEFRSQ RYHMAIVIDE FGGVSGLVTI
EDILELIVGE IEDEYDDEDD IDIRPLSRHT YSVRALTQIE DFNEAFGTHF SDEEVDTIGG
LVMQAFGHLP ARGETITIDN YQFKVVMADS RKIIQVYVHI PDDAPVPELG NDV
//
