ID B4FD59_MAIZE Unreviewed; 103 AA.
AC B4FD59; A0A3L6DSE5; A0A3L6DWL4; A0A8J8YPK0;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 121.
DE RecName: Full=Histone H4 {ECO:0000256|RuleBase:RU000528};
GN ORFNames=ZEAMMB73_Zm00001d002543 {ECO:0000313|EMBL:ONM14629.1},
GN ZEAMMB73_Zm00001d002546 {ECO:0000313|EMBL:ONM14650.1},
GN ZEAMMB73_Zm00001d005791 {ECO:0000313|EMBL:ONM22111.1},
GN ZEAMMB73_Zm00001d008669 {ECO:0000313|EMBL:AQK90411.1},
GN ZEAMMB73_Zm00001d010575 {ECO:0000313|EMBL:AQK94391.1},
GN ZEAMMB73_Zm00001d012439 {ECO:0000313|EMBL:AQK99537.1},
GN ZEAMMB73_Zm00001d020584 {ECO:0000313|EMBL:ONM55158.1},
GN ZEAMMB73_Zm00001d020585 {ECO:0000313|EMBL:ONM55159.1},
GN ZEAMMB73_Zm00001d021477 {ECO:0000313|EMBL:ONM57249.1},
GN ZEAMMB73_Zm00001d026015 {ECO:0000313|EMBL:AQK45299.1},
GN ZEAMMB73_Zm00001d027394 {ECO:0000313|EMBL:ONL93034.1},
GN ZEAMMB73_Zm00001d039733 {ECO:0000313|EMBL:ONM29854.1},
GN ZEAMMB73_Zm00001d042954 {ECO:0000313|EMBL:ONM36601.1},
GN ZEAMMB73_Zm00001d051478 {ECO:0000313|EMBL:AQK54299.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK45299.1};
RN [1] {ECO:0000313|EMBL:ACG24613.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18937034; DOI=10.1007/s11103-008-9415-4;
RA Alexandrov N.N., Brover V.V., Freidin S., Troukhan M.E., Tatarinova T.V.,
RA Zhang H., Swaller T.J., Lu Y.P., Bouck J., Flavell R.B., Feldmann K.A.;
RT "Insights into corn genes derived from large-scale cDNA sequencing.";
RL Plant Mol. Biol. 69:179-194(2009).
RN [2] {ECO:0000313|EMBL:ACF80052.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B73 {ECO:0000313|EMBL:ACF80052.1};
RX PubMed=19936069; DOI=10.1371/journal.pgen.1000740;
RA Soderlund C., Descour A., Kudrna D., Bomhoff M., Boyd L., Currie J.,
RA Angelova A., Collura K., Wissotski M., Ashley E., Morrow D., Fernandes J.,
RA Walbot V., Yu Y.;
RT "Sequencing, mapping, and analysis of 27,455 maize full-length cDNAs.";
RL PLoS Genet. 5:E1000740-E1000740(2009).
RN [3] {ECO:0000313|EMBL:AQK45299.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Seedling {ECO:0000313|EMBL:AQK45299.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact
CC DNA into chromatin, limiting DNA accessibility to the cellular
CC machineries which require DNA as a template. Histones thereby play a
CC central role in transcription regulation, DNA repair, DNA replication
CC and chromosomal stability. DNA accessibility is regulated via a complex
CC set of post-translational modifications of histones, also called
CC histone code, and nucleosome remodeling.
CC {ECO:0000256|RuleBase:RU000528}.
CC -!- SUBUNIT: The nucleosome is a histone octamer containing two molecules
CC each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and
CC two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of
CC DNA. {ECO:0000256|RuleBase:RU000528}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the histone H4 family.
CC {ECO:0000256|ARBA:ARBA00006564, ECO:0000256|RuleBase:RU000528}.
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DR EMBL; BT035047; ACF80052.1; -; mRNA.
DR EMBL; BT035823; ACF80828.1; -; mRNA.
DR EMBL; BT037220; ACF82225.1; -; mRNA.
DR EMBL; BT037283; ACF82288.1; -; mRNA.
DR EMBL; BT038224; ACF83229.1; -; mRNA.
DR EMBL; BT038570; ACF83575.1; -; mRNA.
DR EMBL; BT038760; ACF83765.1; -; mRNA.
DR EMBL; BT039253; ACF84258.1; -; mRNA.
DR EMBL; BT041275; ACF86280.1; -; mRNA.
DR EMBL; BT042209; ACF87214.1; -; mRNA.
DR EMBL; BT043252; ACF88257.1; -; mRNA.
DR EMBL; EU952495; ACG24613.1; -; mRNA.
DR EMBL; EU952528; ACG24646.1; -; mRNA.
DR EMBL; EU952532; ACG24650.1; -; mRNA.
DR EMBL; EU952703; ACG24821.1; -; mRNA.
DR EMBL; EU952956; ACG25074.1; -; mRNA.
DR EMBL; EU953038; ACG25156.1; -; mRNA.
DR EMBL; EU953219; ACG25337.1; -; mRNA.
DR EMBL; EU953382; ACG25500.1; -; mRNA.
DR EMBL; EU958304; ACG30422.1; -; mRNA.
DR EMBL; EU958334; ACG30452.1; -; mRNA.
DR EMBL; EU958566; ACG30684.1; -; mRNA.
DR EMBL; EU958627; ACG30745.1; -; mRNA.
DR EMBL; EU958632; ACG30750.1; -; mRNA.
DR EMBL; EU958633; ACG30751.1; -; mRNA.
DR EMBL; EU958652; ACG30770.1; -; mRNA.
DR EMBL; EU958716; ACG30834.1; -; mRNA.
DR EMBL; EU958718; ACG30836.1; -; mRNA.
DR EMBL; EU958750; ACG30868.1; -; mRNA.
DR EMBL; EU958751; ACG30869.1; -; mRNA.
DR EMBL; EU958755; ACG30873.1; -; mRNA.
DR EMBL; EU958799; ACG30917.1; -; mRNA.
DR EMBL; EU958878; ACG30996.1; -; mRNA.
DR EMBL; EU958927; ACG31045.1; -; mRNA.
DR EMBL; EU958939; ACG31057.1; -; mRNA.
DR EMBL; EU959111; ACG31229.1; -; mRNA.
DR EMBL; EU959112; ACG31230.1; -; mRNA.
DR EMBL; EU959116; ACG31234.1; -; mRNA.
DR EMBL; EU959182; ACG31300.1; -; mRNA.
DR EMBL; EU959197; ACG31315.1; -; mRNA.
DR EMBL; EU959801; ACG31919.1; -; mRNA.
DR EMBL; EU960491; ACG32609.1; -; mRNA.
DR EMBL; EU961309; ACG33427.1; -; mRNA.
DR EMBL; EU962295; ACG34413.1; -; mRNA.
DR EMBL; EU962748; ACG34866.1; -; mRNA.
DR EMBL; EU963833; ACG35951.1; -; mRNA.
DR EMBL; EU963858; ACG35976.1; -; mRNA.
DR EMBL; EU963897; ACG36015.1; -; mRNA.
DR EMBL; EU964186; ACG36304.1; -; mRNA.
DR EMBL; EU964504; ACG36622.1; -; mRNA.
DR EMBL; EU964882; ACG37000.1; -; mRNA.
DR EMBL; EU965132; ACG37250.1; -; mRNA.
DR EMBL; EU965487; ACG37605.1; -; mRNA.
DR EMBL; EU965707; ACG37825.1; -; mRNA.
DR EMBL; EU966694; ACG38812.1; -; mRNA.
DR EMBL; EU967103; ACG39221.1; -; mRNA.
DR EMBL; EU976361; ACG48479.1; -; mRNA.
DR EMBL; EU976372; ACG48490.1; -; mRNA.
DR EMBL; EU976391; ACG48509.1; -; mRNA.
DR EMBL; EU976526; ACG48644.1; -; mRNA.
DR EMBL; EU976575; ACG48693.1; -; mRNA.
DR EMBL; EU977003; ACG49121.1; -; mRNA.
DR EMBL; BT068602; ACN35499.1; -; mRNA.
DR EMBL; BT086626; ACR36979.1; -; mRNA.
DR EMBL; BT086837; ACR37190.1; -; mRNA.
DR EMBL; BT087753; ACR38106.1; -; mRNA.
DR EMBL; BT087814; ACR38167.1; -; mRNA.
DR EMBL; BT087849; ACR38202.1; -; mRNA.
DR EMBL; BT088129; ACR38482.1; -; mRNA.
DR EMBL; CM000786; AQK45299.1; -; Genomic_DNA.
DR EMBL; CM000780; AQK54299.1; -; Genomic_DNA.
DR EMBL; CM000784; AQK90411.1; -; Genomic_DNA.
DR EMBL; CM000784; AQK94391.1; -; Genomic_DNA.
DR EMBL; CM000784; AQK99537.1; -; Genomic_DNA.
DR EMBL; CM007647; ONL93034.1; -; Genomic_DNA.
DR EMBL; CM007648; ONM14629.1; -; Genomic_DNA.
DR EMBL; CM007648; ONM14650.1; -; Genomic_DNA.
DR EMBL; CM007648; ONM22111.1; -; Genomic_DNA.
DR EMBL; CM007649; ONM29854.1; -; Genomic_DNA.
DR EMBL; CM007649; ONM36601.1; -; Genomic_DNA.
DR EMBL; CM007650; ONM55158.1; -; Genomic_DNA.
DR EMBL; CM007650; ONM55159.1; -; Genomic_DNA.
DR EMBL; CM007650; ONM57249.1; -; Genomic_DNA.
DR RefSeq; NP_001131585.1; NM_001138113.1.
DR RefSeq; NP_001278493.1; NM_001291564.1.
DR RefSeq; NP_001281194.1; NM_001294265.1.
DR RefSeq; NP_001288381.1; NM_001301452.1.
DR RefSeq; NP_001313304.1; NM_001326375.1.
DR RefSeq; XP_008650256.1; XM_008652034.1.
DR RefSeq; XP_008656378.1; XM_008658156.1.
DR RefSeq; XP_008657088.1; XM_008658866.1.
DR RefSeq; XP_008668985.1; XM_008670763.1.
DR RefSeq; XP_008668988.1; XM_008670766.1.
DR RefSeq; XP_008673673.1; XM_008675451.1.
DR RefSeq; XP_008674854.1; XM_008676632.1.
DR AlphaFoldDB; B4FD59; -.
DR SMR; B4FD59; -.
DR IntAct; B4FD59; 122.
DR GeneID; 100192931; -.
DR GeneID; 100278340; -.
DR GeneID; 100282268; -.
DR GeneID; 103631010; -.
DR GeneID; 103633162; -.
DR GeneID; 103634846; -.
DR GeneID; 103635780; -.
DR GeneID; 103636523; -.
DR GeneID; 103646024; -.
DR GeneID; 103646028; -.
DR GeneID; 103649716; -.
DR GeneID; 103651039; -.
DR KEGG; zma:100192931; -.
DR KEGG; zma:100278340; -.
DR KEGG; zma:100282268; -.
DR KEGG; zma:103631010; -.
DR KEGG; zma:103633162; -.
DR KEGG; zma:103634846; -.
DR KEGG; zma:103635780; -.
DR KEGG; zma:103636523; -.
DR KEGG; zma:103646024; -.
DR KEGG; zma:103646028; -.
DR KEGG; zma:103649716; -.
DR KEGG; zma:103651039; -.
DR HOGENOM; CLU_109117_2_3_1; -.
DR InParanoid; B4FD59; -.
DR OMA; CNNIRHR; -.
DR OrthoDB; 464846at2759; -.
DR ExpressionAtlas; B4FD59; baseline and differential.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0009414; P:response to water deprivation; IEA:EnsemblPlants.
DR CDD; cd00076; H4; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR035425; CENP-T/H4_C.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR001951; Histone_H4.
DR InterPro; IPR019809; Histone_H4_CS.
DR PANTHER; PTHR10484; HISTONE H4; 1.
DR PANTHER; PTHR10484:SF0; HISTONE H4; 1.
DR Pfam; PF15511; CENP-T_C; 1.
DR PRINTS; PR00623; HISTONEH4.
DR SMART; SM00417; H4; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR PROSITE; PS00047; HISTONE_H4; 1.
PE 2: Evidence at transcript level;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454, ECO:0000256|RuleBase:RU000528};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU000528};
KW Nucleosome core {ECO:0000256|ARBA:ARBA00023269,
KW ECO:0000256|RuleBase:RU000528};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU000528}.
FT DOMAIN 39..96
FT /note="CENP-T/Histone H4 histone fold"
FT /evidence="ECO:0000259|Pfam:PF15511"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 103 AA; 11409 MW; A9FD57725A2A7598 CRC64;
MSGRGKGGKG LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL IYEETRGVLK
IFLENVIRDA VTYTEHARRK TVTAMDVVYA LKRQGRTLYG FGG
//
