ID B4GR12_DROPE Unreviewed; 1348 AA.
AC B4GR12;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=GL25042 {ECO:0000313|EMBL:EDW40197.1};
GN Name=Dper\GL25042 {ECO:0000313|EMBL:EDW40197.1};
GN ORFNames=Dper_GL25042 {ECO:0000313|EMBL:EDW40197.1};
OS Drosophila persimilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7234 {ECO:0000313|Proteomes:UP000008744};
RN [1] {ECO:0000313|EMBL:EDW40197.1, ECO:0000313|Proteomes:UP000008744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSH-3 / Tucson 14011-0111.49
RC {ECO:0000313|Proteomes:UP000008744};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SIMILARITY: Belongs to the TECPR1 family.
CC {ECO:0000256|ARBA:ARBA00005966}.
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DR EMBL; CH479188; EDW40197.1; -; Genomic_DNA.
DR RefSeq; XP_002021041.1; XM_002021005.1.
DR SMR; B4GR12; -.
DR STRING; 7234.B4GR12; -.
DR EnsemblMetazoa; FBtr0190657; FBpp0189149; FBgn0162629.
DR GeneID; 6595975; -.
DR KEGG; dpe:6595975; -.
DR eggNOG; KOG3587; Eukaryota.
DR eggNOG; KOG3669; Eukaryota.
DR HOGENOM; CLU_008303_0_0_1; -.
DR OMA; CPMQISR; -.
DR OrthoDB; 66441at2759; -.
DR PhylomeDB; B4GR12; -.
DR Proteomes; UP000008744; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd00070; GLECT; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR006624; Beta-propeller_rpt_TECPR.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001079; Galectin_CRD.
DR InterPro; IPR010482; Peroxin.
DR InterPro; IPR006614; Peroxin/Ferlin.
DR PANTHER; PTHR23250; DYSFERLIN-RELATED; 1.
DR PANTHER; PTHR23250:SF1; TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00337; Gal-bind_lectin; 1.
DR Pfam; PF06462; Hyd_WA; 6.
DR Pfam; PF06398; Pex24p; 2.
DR Pfam; PF19193; Tectonin; 1.
DR SMART; SM00694; DysFC; 2.
DR SMART; SM00693; DysFN; 2.
DR SMART; SM00908; Gal-bind_lectin; 1.
DR SMART; SM00276; GLECT; 1.
DR SMART; SM00706; TECPR; 9.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51304; GALECTIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008744};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 815..954
FT /note="Galectin"
FT /evidence="ECO:0000259|PROSITE:PS51304"
FT REGION 396..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1348 AA; 149182 MW; 5BCAEDA592FFBD2D CRC64;
MPSTYLFAAS SEGRVYTLST SSGAWRELPY LGLEFKKICA VPNFLWAIGG DRQVYVHVHG
LDVPIRVKEE SYENERWLPI EGFSKTLLPT DRYKYSSADG SVERSVDKIR LPSMAWQWDG
DWHLDLELDG QQLPEDGWMY ALDFPASYSI KKSWNSYVRR RKWKRYRRYA ALNSWCAVAP
LHKDPTQEPF IDVAIGGTNV PNAAAGTLCV WAITAHGRAM FRTGVSKTAP EGLRWTAIAT
PTGSELSQIS VGPTGLVWAV LYNGRVIVRT GVTRDNLSGE AWLDVKTPVA GANLRIVHVS
VGTDAVWCVT NDHHAWFRRG IKGEAAGISE DSAIGKGWVE MVGNVSMVSV APNDQVFAVG
AADRLLYYRS GVTVADPTGK KWRQLQCPMQ ISRTSSSLSI VSRKSGGSSS TPGSKHQSFS
NLYSKEKEKG VVETCAVIET VLHSSAGSSS SNGVGGRLKN ERWKLSADSP PTIGSLNLND
RHKQRTAALR ESSHASSAPA ADVIENSGKF ETQLRNPRAW SPVRSVGSVV GMEAHPESDS
TVFESDSMHH GSDVFLGEDD DHTGSQFWTE CGVLWSCVAP GAVTVDSNNL PNWFNEQAAS
DSKVDVNANW RKDILGKLQR RQEKLVKLQS KTQFEKAVEL SSWIKSADAR YQRPGGDFED
CIIELEWVSG SSSGSNSGSI DGSRSGDSGT FTVLSPDGAA TKIQFPLSDI TCAQCCSEAG
SPRLAIHAPH LPVNCSPVKL QFSSDSEMED WLSHLSSVCS QINTLIGKPA NNAIWLTSDL
GDVFVFDAAT MKAQQMSSGQ GYVERMDVST CETPYYNTLY NGMPCGTELE ISGCVYDDAD
QIRFDLQCHS TVKVQPHRVE KHRVIALHLN PRFNERTTVL NSMKESEWLE EVRNDKVVFA
PGATFTLKIR ALQNHYHIIV NNVVYTDYKY RIDPESVTCL YVSGRIKLFS VLYRCPSVIV
SMQQMHWRQM GGHIKRVYNS GVDVVWGISC DNTAWVYNGG WGGMFLKGLE GSGKINAMID
THTYYVYENQ RWNPISGFTA KSLPTDRHTW SDATGRQKRS KEHTKLLSTH CEWISDWAID
YNIPGGADKE GWQYAIDFPA NYHAHKKLTD CVRRRRWMKR CRLSSSGPWQ ELSQSKVLDA
ALHVLDEDVD SAHDVKNVPV AAWAIASNGD VLIRHGVSSL NPRGDAWEHI ASEQPLIAIS
VGPTGQVWTV ARNGMVFFRY GISRQNPCGD AWQQVEAPAG VTFKAISVGR AGIWALDNQQ
RLAVRKEISR TFPEGSHWQF LPNAANIPPH TEQQCGFRSV SVGAEVWAIS LNGIICRRCG
ITSENPAGVG WNLGIPGQWQ HVSVEGYM
//
