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Database: UniProt
Entry: B4H1B3_DROPE
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Original site: B4H1B3_DROPE 
ID   B4H1B3_DROPE            Unreviewed;       995 AA.
AC   B4H1B3;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   28-MAR-2018, entry version 48.
DE   SubName: Full=GL22583 {ECO:0000313|EMBL:EDW30090.1};
GN   Name=Dper\GL22583 {ECO:0000313|EMBL:EDW30090.1};
GN   ORFNames=Dper_GL22583 {ECO:0000313|EMBL:EDW30090.1}, GL22583
GN   {ECO:0000313|FlyBase:FBgn0160174};
OS   Drosophila persimilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7234 {ECO:0000313|Proteomes:UP000008744};
RN   [1] {ECO:0000313|EMBL:EDW30090.1, ECO:0000313|Proteomes:UP000008744}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MSH-3 / Tucson 14011-0111.49
RC   {ECO:0000313|Proteomes:UP000008744};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
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DR   EMBL; CH479202; EDW30090.1; -; Genomic_DNA.
DR   RefSeq; XP_002024642.1; XM_002024606.1.
DR   EnsemblMetazoa; FBtr0188198; FBpp0186690; FBgn0160174.
DR   GeneID; 6599514; -.
DR   KEGG; dpe:Dper_GL22583; -.
DR   FlyBase; FBgn0160174; Dper\GL22583.
DR   KO; K02577; -.
DR   OMA; NYYRGLD; -.
DR   OrthoDB; EOG091G02CP; -.
DR   PhylomeDB; B4H1B3; -.
DR   Proteomes; UP000008744; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:EnsemblMetazoa.
DR   GO; GO:0000137; C:Golgi cis cisterna; IEA:EnsemblMetazoa.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0045202; C:synapse; IEA:GOC.
DR   GO; GO:0015016; F:[heparan sulfate]-glucosamine N-sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0007427; P:epithelial cell migration, open tracheal system; IEA:EnsemblMetazoa.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IEA:EnsemblMetazoa.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; IEA:EnsemblMetazoa.
DR   GO; GO:0015014; P:heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; IEA:EnsemblMetazoa.
DR   GO; GO:0008587; P:imaginal disc-derived wing margin morphogenesis; IEA:EnsemblMetazoa.
DR   GO; GO:0007474; P:imaginal disc-derived wing vein specification; IEA:EnsemblMetazoa.
DR   GO; GO:0048312; P:intracellular distribution of mitochondria; IEA:EnsemblMetazoa.
DR   GO; GO:0007509; P:mesoderm migration involved in gastrulation; IEA:EnsemblMetazoa.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:EnsemblMetazoa.
DR   GO; GO:0090098; P:positive regulation of decapentaplegic signaling pathway; IEA:EnsemblMetazoa.
DR   GO; GO:0045570; P:regulation of imaginal disc growth; IEA:EnsemblMetazoa.
DR   GO; GO:0007367; P:segment polarity determination; IEA:EnsemblMetazoa.
DR   GO; GO:0007283; P:spermatogenesis; IEA:EnsemblMetazoa.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IEA:EnsemblMetazoa.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; IEA:EnsemblMetazoa.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:EnsemblMetazoa.
DR   InterPro; IPR021930; Heparan_SO4_deacetylase.
DR   InterPro; IPR037359; NST/OST.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000863; Sulfotransferase_dom.
DR   PANTHER; PTHR10605; PTHR10605; 1.
DR   Pfam; PF12062; HSNSD; 1.
DR   Pfam; PF00685; Sulfotransfer_1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008744};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008744};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    183    201       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      210    609       HSNSD. {ECO:0000259|Pfam:PF12062}.
FT   DOMAIN      699    965       Sulfotransfer_1. {ECO:0000259|Pfam:
FT                                PF00685}.
SQ   SEQUENCE   995 AA;  111371 MW;  B0D77E2A7B755937 CRC64;
     MTISSGETTA TATATARATA TARGATTNIH HATAINRNKY EKLITKPRSQ DAIAETETNG
     SASATATATA TPAPIGATTD RTMLLPLEDT NAAAGIVTYK QKSNGSASGS ASGHGNGHIN
     SSGSGSGSTS CSTSSSTSIG ISSSGSGSGG SHLGAGSSYS MGWTCHCCNL IARRCFGINV
     RRCVLALLAI TMVTIFYYTH YVDTDVFNGY KIEVAGKSLP VLTNLDKGRY GVIVFENLDK
     YLNMDKWNRE LLDKYCREYD VGIVGFLSPS EETLVGAQLR DFPLFVNTNL RLRDASLNPG
     SSVLRLTRAG ETAWGALPGD DWAVFQHNHS TYEPVEWAQR NTNEYPADSV GQVQLPLTTV
     LQDRGHLDGI QRVLFGSSLR FWLHRLVFLD SLSYLSHGQL SLNLERMILV DIDDIFVGEK
     GTRLRPDDVR ALVATQKNIA AMVPGFKFNL GFSGKYYHHG TREENLGDDF LLQNVQEFNW
     FSHMWKHQQP HLYDNLTLLM AEMHLNYAFA VDHNIPTSSG YSISPHHSGV YPAHELLYVA
     WKKVWNVKVT STEEYPHLRP ARLRRGFIHR NIMVLPRQTC GLFTHTMYID RYPGGRDKLD
     ESIQGGELFQ TIVYNPINIF MTHMSNYGSD RLALYTFQSV IKFLQCWTNL KLASAPPIQL
     AEMYFQLHPE EVDPVWGNPC DDARHKKIWS KTKNCDSLPK FLVIGPQKTG TTALYTFLSM
     HGSIASNIAS PDTFEEVQFF NGNNYYRGLD WYMDFFPSGE ALSLPPSNSS SPSPMPTQAG
     SPRYMFEKSA TYFDGEAVPK RTHALLPHAK IVTILISPAK RAYSWYQHQR AHGDVIANNY
     SFYQVITASD SAPRALKDLR NRCLNPGKYA QHLEHWLAYY PAQQVHIIDG DQLRLNPIDV
     MNDLQRFLKV QPLLDYSNHL RYDVKKGFYC QALNEKRNKC LGKSKGRQYP TMDERSGKLL
     QRYYLNHNTA LVKLLKKLGS RPIPQWLKED LSTGT
//
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