ID B4IE46_DROSE Unreviewed; 1953 AA.
AC B4IE46;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 73.
DE SubName: Full=GM26440 {ECO:0000313|EMBL:EDW45873.1};
GN Name=Dsec\GM26440 {ECO:0000313|EMBL:EDW45873.1};
GN ORFNames=Dsec_GM26440 {ECO:0000313|EMBL:EDW45873.1};
OS Drosophila sechellia (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7238 {ECO:0000313|Proteomes:UP000001292};
RN [1] {ECO:0000313|EMBL:EDW45873.1, ECO:0000313|Proteomes:UP000001292}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Rob3c / Tucson 14021-0248.25
RC {ECO:0000313|Proteomes:UP000001292};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH480831; EDW45873.1; -; Genomic_DNA.
DR RefSeq; XP_002042006.1; XM_002041970.1.
DR STRING; 7238.B4IE46; -.
DR EnsemblMetazoa; FBtr0209425; FBpp0207917; FBgn0181293.
DR GeneID; 6617694; -.
DR KEGG; dse:6617694; -.
DR HOGENOM; CLU_001454_0_0_1; -.
DR OMA; AYEQFTP; -.
DR OrthoDB; 5491602at2759; -.
DR PhylomeDB; B4IE46; -.
DR Proteomes; UP000001292; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR46866; GH12955P; 1.
DR PANTHER; PTHR46866:SF1; GH12955P; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001292};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 333..611
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 1654..1689
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 617..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1103..1142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1116..1134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1953 AA; 217446 MW; 2235918381181D9F CRC64;
MGDCEQIWPE IGVDPQHVCE AGGDGRFQVI CDKAWLQSLE RNRRLTHFPS WPLLDRRSYP
TGQLEHPWTR ILVQTYRKQP QSKVYPLPRI SGDAPSSELP LSYSQAVSFV AHSNFKQLWE
EAYRKYNGAH VKMCRSTPSA PSTKPPSGQG QLQPHDVVLK ELIQRVYQCP VLHCQLDRDG
LSESSSATSF SAGSCHANVL PALVAIESSM HISVFFYPPA LECSLYDCIT FSPALLGKNY
NKTLFVLYQI LQLAKHLQGQ GLFLGDLRLH DIVLRENLWL QVLPRLQCNL LDDDPAGEDM
SPLTPLASED LGEAREAQQP LPSSSTMFDL RFAYDPAHFN LREYAEMWCN GQLSNFDYLT
ILNNACGRSL TNAAYHHIMP WVTDFSGRGG GAWRDLTKSK YRLNKGDVHL DLMYAHASQH
GSADGGYQAI GDQAPHHVSD FLSEITYFVY MARRTPQAIL CAHVRPIWVP AEYPVSIQRL
QEWTPDECIP EFYSDPMIFK SIHEDLPDLE LPAWASCPED FICKHREALE SQYVSERLHH
WIDLNFGYKL SGKAAVKSKN VCLTLVDQHR NLSQRGIVQL FASAHPPRRY ATPWFSRTAP
RLSQLYASPA KRLAKSTENL HAESATGSSH LSLRLGDDGS SGSVHSSSAS ASASNFYAIT
NFIELPENYN PALLLHNLET LEAFYARTFP QQRASANPEE KMISSDMMFE QNSAEHSFTN
QLFASGDEIP PKSKNLLREK RNCLQHLLNA RKERDLHVLG CLIIELFAMQ RLRPLLMGNG
LTATFDSRLS ACRTVAQLHR QELPKPVRRV VRLLLQLEEP GEVDQGLPQP PNPAQLLEPM
FSNLLLPFPS HYMAVYALVR SLHAFEANAV LLELHTHFSC KGGRECDRYT EMDRQRVLFE
RKIAECKVMS CCAHVKRLLE PMAFAYEQFT PVELLLPHII DLLRDERTSI LTAWNLFDPI
AQALGVSQTQ QHLLQPLLKL YDVESVSSPD DGGSNGSTNS GGHLRFSASS SFKSRKSVKL
YHHSFLLRLI VRFGLRCFLH HFIAPLIEAV GGYKEPEQGN GYHYHSGGSR RTSKNLNFAS
ENEVHQAVVA PEIKPDIEEL FTFEDDHDRA STQDSKSTDS FDMRPSTSAA SAEEARESDG
SPDKLVINEL IYGARISPDK LSLKESQTPP ALVPPPIGPR SPTIEIPMGP TAGGIRRSFQ
LSAIDCDIGS RKSVDSFELI SQAVEQLPPP AEQSEAEASD SLQASVISRL SEAKAVQNNR
ISEMSAESLV WLSHRLGPVL TSRFITRNLL KLLSLCYVGQ ENLLPEVDDG GSSFNSSPDA
ANLNYFSIAN ARVVGDRSAA RVLECLMSIA ALYGENFLLL QYFPHISELI SLCSKRITGS
LEGAIISSLQ LLKYMVPCLT DASIMEHLQH IMLDAILLPI LRLLSSTNLV MPSGYLGRSL
LARKFLDAIY ALSVRLGSDM TREHLCQPLL NPFFLIFNKA FGLPNDFACD LANLSLVGGA
SQPERALEEL RDVFGPELAH TAYLTFLRFL GEANMKRTLS NLDFVLTLCH EHEQPNGQNK
IQLATSVSSG QDVDSLDASC ELAANSFGTQ IVGNRLQVAR NNVELIDMVA YKLDQMPKTR
HLKGNWLAYW RNETTRNEKD TQTLNLKQIR LQSFVGHTNS VRAIYALDNE NSFISASKDK
TVKLWSLRSE GDGRKTSACQ FTYTAHKKSI NSLGFLESLR YVVSCDSGIH LWDPFIGRPL
GVLDAPRHSA VTVVKCLPSH SPLVIAGTAE STVKMVDARS CEYVNEWRVC NASLPNATVR
CLAVAPSGNW LAAGLSSGCI VQLDTRTGMV INSWRPMECD LLQLAAPSDQ FLVSSALDHS
LAVWHALDGI MHYQLKPPPE PAHFLQSVGP SLVYATTGNR VGVYADVTHS HAFSTITKLR
SETFRGVLTS LAVLPLNRAF LAGNESGNIA LLC
//
