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Database: UniProt
Entry: B4J860_DROGR
LinkDB: B4J860_DROGR
Original site: B4J860_DROGR 
ID   B4J860_DROGR            Unreviewed;      1324 AA.
AC   B4J860;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   31-JUL-2019, entry version 68.
DE   SubName: Full=GH21300 {ECO:0000313|EMBL:EDW01197.1};
GN   Name=Dgri\GH21300 {ECO:0000313|EMBL:EDW01197.1};
GN   ORFNames=Dgri_GH21300 {ECO:0000313|EMBL:EDW01197.1};
OS   Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Hawaiian Drosophila.
OX   NCBI_TaxID=7222 {ECO:0000313|Proteomes:UP000001070};
RN   [1] {ECO:0000313|EMBL:EDW01197.1, ECO:0000313|Proteomes:UP000001070}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15287-2541.00 {ECO:0000313|Proteomes:UP000001070};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
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DR   EMBL; CH916367; EDW01197.1; -; Genomic_DNA.
DR   RefSeq; XP_001986330.1; XM_001986294.1.
DR   SMR; B4J860; -.
DR   STRING; 7222.FBpp0155206; -.
DR   EnsemblMetazoa; FBtr0156714; FBpp0155206; FBgn0128762.
DR   GeneID; 6559303; -.
DR   KEGG; dgr:Dgri_GH21300; -.
DR   eggNOG; KOG1817; Eukaryota.
DR   eggNOG; COG0571; LUCA.
DR   InParanoid; B4J860; -.
DR   KO; K03685; -.
DR   OMA; EYLYRHF; -.
DR   OrthoDB; 935825at2759; -.
DR   PhylomeDB; B4J860; -.
DR   Proteomes; UP000001070; Unassembled WGS sequence.
DR   GO; GO:0070877; C:microprocessor complex; IEA:EnsemblMetazoa.
DR   GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030727; P:germarium-derived female germ-line cyst formation; IEA:EnsemblMetazoa.
DR   GO; GO:0007294; P:germarium-derived oocyte fate determination; IEA:EnsemblMetazoa.
DR   GO; GO:0016319; P:mushroom body development; IEA:EnsemblMetazoa.
DR   GO; GO:0031053; P:primary miRNA processing; IEA:EnsemblMetazoa.
DR   GO; GO:0016075; P:rRNA catabolic process; IEA:InterPro.
DR   GO; GO:0035070; P:salivary gland histolysis; IEA:EnsemblMetazoa.
DR   CDD; cd00048; DSRM; 1.
DR   CDD; cd00593; RIBOc; 2.
DR   Gene3D; 1.10.1520.10; -; 3.
DR   HAMAP; MF_00104; RNase_III; 1.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR011907; RNase_III.
DR   InterPro; IPR000999; RNase_III_dom.
DR   InterPro; IPR036389; RNase_III_sf.
DR   Pfam; PF00035; dsrm; 1.
DR   Pfam; PF14622; Ribonucleas_3_3; 1.
DR   Pfam; PF00636; Ribonuclease_3; 1.
DR   SMART; SM00358; DSRM; 1.
DR   SMART; SM00535; RIBOc; 2.
DR   SUPFAM; SSF69065; SSF69065; 2.
DR   PROSITE; PS50137; DS_RBD; 1.
DR   PROSITE; PS00517; RNASE_3_1; 1.
DR   PROSITE; PS50142; RNASE_3_2; 2.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001070};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001070};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT   DOMAIN      735    915       RNase III. {ECO:0000259|PROSITE:PS50142}.
FT   DOMAIN      967   1090       RNase III. {ECO:0000259|PROSITE:PS50142}.
FT   DOMAIN     1117   1192       DRBM. {ECO:0000259|PROSITE:PS50137}.
FT   REGION        1     48       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      309    329       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1207   1324       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS      1     29       Pro-rich. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1212   1255       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS   1272   1324       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   1324 AA;  152069 MW;  DB49997A7B95A868 CRC64;
     MDQPPLPPPQ EYSTLPPPPP PPPPDTEHLL PPGVQDDGPP GTSDVPIAAS NQFNYEQHPS
     SVNNLNDDHS SYANYMKYAA PHSACPQQSQ PYAANSGPHS YNPYYYHEGY AGHTNYAHPS
     AGAYDYDQYG QSTHTYNYQE RNRYEHNSNY RLVDQRYAGY NHSYPNNYGG GYNYNNNNNS
     RYEHHYHNPR QARTGSYPYA RKTTSVNEDT RSYSKRSESD AYAPKIETER DRVLRQYCAN
     YCEKSEDYIK KIKALNEAEA PAETWVRSSP AELYYERTKT EHEVKAKTRL HKLCALFDDE
     LIQRAVRERQ NLPAYEPPPR KTRRRACKHK HKSEACSSSS DSDSDEDAFK IEQDCCMEEL
     SRKVLHPQRV HPDLWHNDAG EMNDGPLCRC SAKSRRIGIR HGIYPGEKGY LVCDKDTNNA
     ANLYHYRITI SPPTNFLTKT PTIIKHDEHE FLFEGFSLLS HVRLTDLPVC KVIRFNIEYT
     IEYDEEKMPE NFTIRELDLF FKYLFHELLE LVDFNLIPNG SANADDSCPA FHFLPRFVRE
     LPDNGKEVLA MCEVLKYLLD NSAELVERQQ LLHLNQISTH EWQKYVDIIK GMLVTKPGHK
     PCSLRVDQLD RNNSDLPVCL DRETGISHPA IVHFGIRPPQ LSYAGNPEYQ KAWREYVKFR
     HLMANMSKPS FKDKRKLEDK EQRLQEMRTQ GRMKRNITVA ISSEGFYRTG IMCDIVQHAM
     LIPVLTGHLR FHKSLDLLEE SIGYKFKNRY LLQLALTHPS YKENYGTNPD HARNSLTNCG
     IRQPEYGDRK IHYMNTRKRG INTLVSIMSR FGKDHETLSN ITHNERLEFL GDAVVEFLSS
     IHLFFMFPEL EEGGLATYRA AIVQNQHLAL LAKKLQLEEF MLYAHGSDLC HELELRHAMA
     NCFEALMGAL LLDGGIKVAD EVFTDALFRQ DDKLLKIWKN LPEHPLQEQE PLGDRSCIDS
     YRVLKDLTKF EDSVGIKFKH IRLLARAFTD RSIGFTHLTL GSNQRLEFLG DTVLQLICSE
     YLYRHFPEHH EGHLSLLRSS LVNNRTQAVV CDDLGMPQYA VYANPKADLK TKDRADLLEA
     FLGALYVDKG LLYCEQFCHV CLFPRLQLFI MNQDWNDPKS KLQQCCLTLR TMDGGEPDIP
     YYKVVEATGP TNTRVYKVAV YFRSKRLATA SGSSIQQAEM NAAKQALENS RDLFPQLDHQ
     KRVIAKSIKK QTGNEMDTEA DRPHDERAKK PKYAPPLKDE SHLPKQYRMH ENISSDELPE
     DDEDDNDNTN KTLRSPVHVS RSRSRSSSSS STSSDSDSAT STPPKQHPDL LYGSISPVSS
     SSSV
//
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