ID B4J9H7_DROGR Unreviewed; 1785 AA.
AC B4J9H7;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=GH19861 {ECO:0000313|EMBL:EDW02484.1};
GN Name=Dgri\GH19861 {ECO:0000313|EMBL:EDW02484.1};
GN ORFNames=Dgri_GH19861 {ECO:0000313|EMBL:EDW02484.1};
OS Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Hawaiian Drosophila.
OX NCBI_TaxID=7222 {ECO:0000313|Proteomes:UP000001070};
RN [1] {ECO:0000313|EMBL:EDW02484.1, ECO:0000313|Proteomes:UP000001070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15287-2541.00 {ECO:0000313|Proteomes:UP000001070};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH916367; EDW02484.1; -; Genomic_DNA.
DR RefSeq; XP_001987617.1; XM_001987581.1.
DR STRING; 7222.B4J9H7; -.
DR EnsemblMetazoa; FBtr0463188; FBpp0413527; FBgn0127325.
DR eggNOG; ENOG502QRG4; Eukaryota.
DR HOGENOM; CLU_001989_0_0_1; -.
DR InParanoid; B4J9H7; -.
DR OMA; HSQNADK; -.
DR PhylomeDB; B4J9H7; -.
DR Proteomes; UP000001070; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR013606; I-BAR_dom.
DR InterPro; IPR030127; MTSS1/MTSS2.
DR InterPro; IPR006601; Uncharacterised_DM11_DROME.
DR PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR PANTHER; PTHR15708:SF4; FI21477P1-RELATED; 1.
DR Pfam; PF08397; IMD; 1.
DR SMART; SM00675; DM11; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51338; IMD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001070};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1785
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002808399"
FT DOMAIN 175..424
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT REGION 454..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 636..660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 673..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 789..825
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 858..878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 907..931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 955..1002
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1185..1320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1352..1385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1403..1435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1536..1637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1749..1785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..499
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..588
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..624
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..660
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 961..1002
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1201..1242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1254..1284
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1298..1318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1542..1609
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1622..1637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1785 AA; 193456 MW; 067C634066F457E6 CRC64;
MWTIFLLFGL SCQSVLSANY EFLPEDPDIF SDCRNPPGPP GATNIKGLFS LDELELSLIG
DMVHIEGNLT TVWDIQPTDR IYAAARVMHW NRGVWQSTVF DLHTKDLCKI LYDKAQYWYT
AWVRHVTNVD EVRSKCLYLK DGLKIIHEPF DLKMVYENIQ GVKLYGRYKI VIIMEAFEEH
KNIKRPTTVC VEIIGDNTSP LWDDFVAKAS KLHTCLRAAI QAIAAYLDAF QKIADAATNS
RGASKEIGTA LTRVCLRHKA VETRLKTFTS AIMDCLVQPL QDKIEDWKRT VATIDKDHAK
EYKRCRSELK KRSSDTLRLQ KKARKGQTDN SLQSLMDSHM QDVTLRRAEL EEVEKKSLRA
VMVEERLRFC SFVHMLQPVV HEECEVISEL GHLQEAMQSI ALVTKEPSVL PPASEELIHD
AKASINLYPE SPGGGSGSQG GGCSNSLGSR KSSVCSISSM NSSGSSNSPG HHHYPRSLSQ
ASNATNQTHA VSTWPPHSQD VVDTLPPTAD RPHTISTTYE KGHQRPPLTV YTFQNPETIP
ESSSSGSLNP ATVAANQPTN TNSNSNTNGS ATNSGQNTPA TQKSPAASLS RPPLPVRCSS
LERPLSAQSN QRQNSGQNLL QRQCPSPIPA HITKELSAAH HAQQQQSQQQ QQQQQQQTPP
TYVNMSELAA MKLTNQQQQQ QQQQQQSQQQ QKSSTPLLQQ QSSIDSICSQ HSNDSSTSSL
QQQLLQHNQQ QQQQQQQQSH MNHQSGSGLG TRSHSISSSV SSNTASSSLH SHPSIDSAVA
ASLVAAGGNT NTSTTTPSSG CSTPQNHYSP LLTNSPTSTA AGTPSGGSIA SGLGFIYQVS
SPTPPTSASD VLKITEPGAG TAVAPPDVHS ESADSDERSR ASVLQKASMF EKQAAAAAAT
VAAPAPPATV PAATTTRRSE ELRAVEQQEM DKSFEDSIQA LNNLIGELDS FQREIDEGKG
SKQQQCNTNS NNNGINNNGN NNNSNNSSSN SSNSNENNNC NDLLMPSSSI NIECCAISNQ
TNSSGCGTDI SDTTSEELGA DESGGLAAAR RHQQLGASDS ELSRCYVSET SSLTGGILAG
GYENPTFAHF ANREDPSGGC SSSLYAQSAA DSISLATSDS LCQQRHAYVD TCSDDGSAVV
VIYDHQIPNT PDIEFVKQNS EIVLLRHKDP QQLQLHEMRE LQQLPDNLSG SPESPDGGSG
GGIGGSTTAS GSKPATATVA PAKQRLSSFR ASSEQQLQLL GRASPHRGTE KLRVSVDQQQ
QQQQQQQHLL ANDSSSSSST VRRKLPPKPI SLSIFNGPSL EAAGNSSSSN SSSSSKPMIP
RKFDFKADLD AKIRKQKLKV QQQLQQQQEQ QQQLQQQQQQ PQQQQQQPPH SPQSPQTTTT
TTTTTATTAA NCNVTNKTAV TASASNSIQQ NHRMPNQYQT QTSTTSTNHA PYKTPTTAAT
FTTTTSALSS NSSLLLSAIS PGAKLPLPLS SSTSTSTLSA TAAATTTTML APASLPPPLP
PVPAKPTPSN SYMCSTTANA NANAIANPHA KPCITPRPAS LSGLGGGSSS TRIARRSSIN
QAKPPPPVRR SSSVTPSPNV GQQQQQQQQQ QQQQQQQQQL NSNNLYSSDH LPPPPAFMLE
ASAYSTSPTP NSMPSSALKV SETVRALAAM RHQPASPVAL RRMQQQQQLQ LQQQQQQQQQ
SLQQTVHKQS SSDEADYEGY YNSYMELHAY AHASQAPQPT PQATYPQQQQ YQLQQQQCYI
QLQQQQQQHL HQQHHLHHHH QHQQQPPTSP PYQGPPQLDA VSATT
//
