ID B4J9V2_DROGR Unreviewed; 5298 AA.
AC B4J9V2;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE RecName: Full=Midasin {ECO:0000256|ARBA:ARBA00017143, ECO:0000256|PIRNR:PIRNR010340};
GN Name=Dgri\GH20407 {ECO:0000313|EMBL:EDW01516.1};
GN ORFNames=Dgri_GH20407 {ECO:0000313|EMBL:EDW01516.1};
OS Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Hawaiian Drosophila.
OX NCBI_TaxID=7222 {ECO:0000313|Proteomes:UP000001070};
RN [1] {ECO:0000313|EMBL:EDW01516.1, ECO:0000313|Proteomes:UP000001070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15287-2541.00 {ECO:0000313|Proteomes:UP000001070};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- FUNCTION: Nuclear chaperone required for maturation and nuclear export
CC of pre-60S ribosome subunits. {ECO:0000256|PIRNR:PIRNR010340}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}. Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the midasin family.
CC {ECO:0000256|ARBA:ARBA00007188, ECO:0000256|PIRNR:PIRNR010340}.
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DR EMBL; CH916367; EDW01516.1; -; Genomic_DNA.
DR RefSeq; XP_001986649.1; XM_001986613.1.
DR STRING; 7222.B4J9V2; -.
DR eggNOG; KOG1808; Eukaryota.
DR HOGENOM; CLU_000050_0_2_1; -.
DR InParanoid; B4J9V2; -.
DR OMA; ILEQWHR; -.
DR PhylomeDB; B4J9V2; -.
DR Proteomes; UP000001070; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd01460; vWA_midasin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 6.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR040848; AAA_lid_7.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR012099; Midasin.
DR InterPro; IPR041190; Midasin_AAA_lid_5.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR48103:SF2; MIDASIN; 1.
DR PANTHER; PTHR48103; MIDASIN-RELATED; 1.
DR Pfam; PF07728; AAA_5; 6.
DR Pfam; PF17865; AAA_lid_5; 1.
DR Pfam; PF17867; AAA_lid_7; 2.
DR PIRSF; PIRSF010340; Midasin; 4.
DR PRINTS; PR00830; ENDOLAPTASE.
DR SMART; SM00382; AAA; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 7.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR010340};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|PIRNR:PIRNR010340};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR010340};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR010340};
KW Reference proteome {ECO:0000313|Proteomes:UP000001070}.
FT DOMAIN 5094..5288
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 4278..4298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4368..4950
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 4081..4108
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 4278..4296
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4395..4451
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4452..4472
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4473..4487
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4488..4503
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4504..4581
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4593..4626
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4627..4656
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4683..4697
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4706..4730
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4731..4753
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4754..4775
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4791..4848
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4855..4892
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4893..4918
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4919..4950
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5298 AA; 605313 MW; 4D41ADBD8B3D4E78 CRC64;
MDVKINKLRR SVQQLLQLTA SEPQDDVFVL NLQKFLKKKR YVEQDVERLF NSLSQQLTMP
GYTVPLAMSF EEELLLLLTM SLRWDPAVHA DQYKSECIAL AKLLHLSVDA KRFAKSYFRY
RPAPFEKQQS NEHVQIPSKR TKKTHTNGVL ETKKQQLDLE LVKCCYQLLS SDAVYYRELW
DWSQFLANYS DNSVKCQLSQ LYCNHIMAML TDMSSTQLHT LNAQIPVKVQ LQFDEHQTLA
THTKFDYSSD LPEQHLTLKL EKANQSVTNI EGVILPIFNK DNQTFYADTD GCYDRIVKVD
SSIVNLRSIA LGVAAAKPIC LSGPVGCGKT TLIEYLARKT GRICPKPKEI EIRDKAKREA
EEDDELLKPK RKQKAIKNAG EKRKIADVPM EDLMVLEDGD GLAQRNGFLR IQLGDQTDSK
MLLGQYRCTD VPGEFVWLPG VLTQAVMHGY WLLLEDLDAA TQDTYTILSS LLERNYLSVP
GFRDCVKIEP GFQLFVTVRT NKSSNNYSQK SLFSLLEKYL YTINILPLSR NELCKVVSTN
YERLATVANR IVDVFLTFSS GDHMSADNLR QQESSDKADT TEKYVALPFE QVASTGIPNS
GRLVSTRDLS KEKTALITNI GAKLGIIRSR CEHFANEYKP DVEFGKQSFK IGRATLPTIS
VEEEKAQSAS KRQKLTLQTQ KTISKSSVKR ATFSFTRLAS CILERIAVCV SHSEPVLLVG
ETGVGKTSSV QYLAERTEHK LVAINMNNQS DVSDLVGGFK PVELNYVLAP LRYEFEHLFG
ETFNADKNLQ FLRIFATHFN NGRHSVIIRT MLNVSNSILC KEEHKLNPLL PRWRTLHEKL
QRLQTQLEKS INISFAFIPG SLVNSISNGD WVLLDEINLA SAETLECLST ILEPEGSVVL
LERGDFMPVK RHPDFRIFAC MNPNTDIGKK DLPVGIRNRF TEFFVDELTT DADLGLLVGD
YLANTGIQRK SVHSIVQLYK SLRRLSELQL NDGLGNRPVY SLRTLCRSLR ICARNLCGSI
ERNLYESFCL SFLTQLDPES HQLVLLLIRD ALLHNAKVVL NQSLPRLGEN YLQFEGYWIQ
NGSLELQSCA HYILTGSVKK NLQDLARIIS IGKLPILLQG PTSAGKTSLI DYVARRSGNR
CLRINNHEHT DLQEYIGTYA ADVSGKLSFR EGVLVQAMRH GYWIILDELN LASTDILEAL
NRVLDDNREL YIAETQTLVK AHPNFMLFAT QNPPGLYGGR KTLSRAFKNR FIELHFADIP
RAELEIILEQ RCLIPASYSR KMVQCMTQLQ QHRKNTSKQV FTLRDLFRWG NRYTLADKAL
QQDHKYDWNQ HLIEEGYLVL SAKVRSSEEL QLIEKTLYGN FKKRIDLELL FDIQTKRESS
AVSRHILDAI RNFKQRGDIV WTRNMTRMAV LTAKALQFDE PVLLVGLTGC GKTTVCQLLA
SIAQVRLRIL NCHMHTEGAD FLGGLRPCRG QQNGEQQAQK LFEWADGPLI YAMLEGSYFM
ADEISLAEDS VLERLNCILE PERSVLLAEK GGVVEEDVTV SESNLNKDFI VQAKSGFQFL
ATMNPGGDFG KKELSPALRN RFTEVWCLPS DNKSDLIEIA HNCMQRGSAS ATSVTSSSSH
KIAEYLVEIV LFIRDSNEKF KFSVRDILAW ANYMVSNSHL TFAEQAIFGL ETIFLDALEM
LPHESQTQIE ALKCRIIDHA IRQAAVILDE HFELSYVDEK RGQQVQLDEK RFGIRPFFIN
VNPERLMPAN AEFLFDAPTT KQNLFRLLSA LSLQKPVLLE GPPGVGKTSI VESIAHAIGY
QIVRINLCEH TDLADLFGTD LPAEDNLLER VEAQSQLGSF VWRDGPLLAA LKATRTWILL
DELNLAPQSV LEGLNAVLDH RGEVYIPELN KSFQLTDSTR IFACQNPLKQ GGGRKGLPQS
FLNRFNKVYL RKLTTEDLLH VVNVKYASYF DQLNTYFNAL LDAEQLPKGN VFDLYNGHSS
EIAATEISFD LAMRLVRFSE VLDRGVATME FGYKGGPYEF NLRDILRWCD LLHNPATGYL
MLPGVNNFHG AFHDFLLTLY ERMQLVYYQR MRCDQDKLYI RNAFQGVFNC NAEQLNAIAE
DVAVYWTADK VYLNDVVLER EPLALGLAAQ RQEQAPLLLA TQRQQLKQIV ETVHMEKPLL
LCGATDSGKT KLIDALCVLS NRQCNSDNID DSVTGSFQQF QCSFTDQCRY LPFFEESQQH
SVAEELELFA HRLVALDEII AKLEQTPLEC RVPLFEQLTQ NKSQLLLLQT YIKSADSLNT
GGSFEWVDSN IVTSLKCGQY ILLEHVNLCS SAVLDRLNPV FEPNGSLLIA EKGISAHDSA
EVVQRSPNFR AFLTIDPKNG ELSRAMRNRC VELSLSMSKD AYSIDDMRAI VHGQGVHHTA
AIDCMLSIHR NIAQLTEFNS YTISHLTHFA FLSAAYKRIG YELKRAIYVA AMEVYVYAAS
MDLMGYGLAY YQNKLREVVL TQTEAYVEGE EEQEDYLNDV ILRTDELNAL TLIKLQTVTL
KLLLQSSTDG ELPKAQLISL FQSMSALDLN RLSVNQISRF LIYMLYEMSA FGELHMRHLY
MQQYLKAQPE LQQLSFSLYD CLMQQGKRFQ TSLTNLPWHR KLFPRLRDYA TQPPSRDAGP
DAALALSASL LAQLLVAQIP KRVVTQLQHM DALQYSQALL DKKITEKYTL RESLEQLTSY
VQDTKRPMNV SCKIYAKQFT QFQPYYLDTQ ITLHEKVSQL QQLLNVVPQY GNMDSKLWLH
KWLALQSDEA HKWRAFLRTH ITSCQMKQFE LNDACICNGE LQAALRRLQH QLKEQQQQQP
DQDESIFIDI EQVRQKLTAS WDGAEDEHLV DLNAGELKSY QLLQAALRDY FMDRALSRTL
HPDFDEQVNQ LYSEQLLTLN GHMWQCLNTL SSATHGNIML AWRELSQELH SPAELVSLLQ
QQLGSSSCYK ALRSYQRQFR QALQCYQLEN LATRFDCAQV PSDVELGSRY SYQGPALSNA
LLSLVCQSNG QLLSVPLSEL QPWRQTLQQT RQLLWQNAQL QSRRHSPEVN NLQLVQESGR
QLLNELEYVT HVQQEQMQQQ QQMDAGFERC IQELQQVLQQ LQLPQDQTEP LSSSFNAALA
NTLIGVLELC VLTHAPLIDP VEKNRLKNLY IAEDIDCLVH FSAAHDFMRI IMNYKHFGQQ
IYEQVQQRLH SAQQQQQQLN QKLALRPDQC LYASLVQDLM HFLKSNCDCA ALHKLIKVIR
ENWSHFLGKQ AASEQQLRRG AELLNKLELW LANAQRFVHH TLARYEAYYQ DFVLPIKCAV
NQMRFGLEQL KQLFSRLLMA GSAVEAIKLE KTIAQIGEFP AQRPLAIRNT HVYGLLAKLP
HSEHEYFRLL KAKLTELRNF ISIASSIDET IFAAYDDALS ICNRTWQQEE QRRNEQRAEE
ESLYKTKTLG GVEDEELEAL QEIEQHFPTN LDEDFAEFVD QPTLEQVLKL DKKAATKAKL
AQIVNEQDYV FLARNFIESM TRYTTVSYKD REQQQREKQE LQLIQPYQAR LQVFVQLHGH
YKTAVGATLD DSVYNALTFA LAVQQRQLQD IHLEESHSSP TYDFYKDSNI TEINGCLDVM
ERIEKRVLEQ LELYPEHAGL ADIKLVISRI RKLPANASVV RFNTGFQLLR QKLALWNELA
HRNNNLVAEE IEVAEFVQRW TKLELQHWRN CLNQTAQLVE LRAYRYWFFI YNLLQGGAAD
LPESIRTLRQ FVEASCYGDF HVRLQLLHGF EMYLHNVERA GKAKMDVPPI IAALHNLQLY
FAQFAQEVAD TVKLRRVPIE KKLREFVKIQ SYNKDLSYFS MRNNVASVHR NLGKFLKEYR
LLLEQKISEV FQPKDSTVKD YSMDKSRYKQ KFDLYLLDSQ HFVAPQQLRD KYSAVDLGSD
SGSDSLPLLQ QLGKHFGTAR NIVRQTLSHT EYGPLLTELD ELVTAQLERC EQLRNLNVDR
SKERPQQKLQ AKQILQQKRK ALTDLFKLLT RLGISYKSGL MELSLRGEFE NFELAPFCIE
AMLPQLHSSG RQFNQQLDLY YMKSVFKLKL LQNIMLTPLS ELGPPNIERI KGFAVDLFLH
VQQQREQLST ATRQLHELRN ALHQLRHVAD IVMPTEATIE QLSFSRNADE CVQLKHKLCQ
IQYVLRQWQL LLQCAPLQAT NEHSLCGVIL SGSQALLFEL ERASLEFLDS NKLSIYLRSY
QTILDNMQKT LAHLNAGHEE HLPLAQPLLA LLAQLESNTA CDVSSGEPVE LNNVDAELAN
IAHGVLLALQ KIYKQHGKQE EKQETEEEDS LKEQHLKQHL TGQLNADWQL LRMPRTLSKL
SNVLLVLKHA NPSEKQLICL RRAVSAKMLS IMLTAFVEIG SKGFCVPPDL MQDEEGQSKQ
DSKNGEGFGL EDGTGENDAS DKIESEDQLD DAKRPEDRKD EGDKEEPDCK EEKGIEMSDD
FDAKMQDVEK PENEEDDSGE SEDEDELNKE MGETEEGAEK LDDQIWGDDE EKQPEEEEPD
MNEEDQGKGT KDEKDDHNDL DTKNDAAKED GKDEHEKDAL DATSEPSGED KRKEQAKDID
DMKEPELDEE QTNAMHNELE EPPEPEEMDL GDMNNVDEGH DKDADEPNDE NPFDIDAMKE
NMQAADEPDE ADADEEEAKE SQPESDDSDS EAEEGGTENE TTQNAKDNAE EEEASAEDEK
EQEEPETQTR GELNKEEEEQ EEPPVEPEAR EEKPEEHAQS KDKSSKEDNV QSVPDTEQNS
SAEQMQQQQQ DENIKQEQKM DEQETGEEKD GVGQAENDTN DGGHQGVAET KETISQEERK
NEKQTQEKRK QGRTNEERTL GEAEQTKLKQ LKTIDQMKES KQNENEQQDQ TDENVEADEY
QHVKDPKSSD KTTLDNATEE QSKQIKHQEE EEATEEENAD VENADELMAD EEPTAHEEED
AQLEQLSCEK TDQKSEKPSK TEQAKERLET PEQMEIEGEV VPTMTVPRST ETTAHSNTEL
LLDKSTLAQE LSTTEQIELR QMYQQQLTSS NAILPHHEDY ESWSSISNRM TQNARELCEQ
LRLILEPTKC TRLKGDYRTG RRINMKKIIP YIASQFRKDK IWLRRTKPAQ RDYKITIAID
DSKSMHHNNS KTLTLEAISL VSQALTLLES GRLSIVSFGE APQIILNHTE QFDGPRLVSA
LNFAQDKTKI AGLLDFIRTV NIEESGLGGD NGLFENLLLI LSDGRNIFSE GNQKVKNAIK
LARLQRIFLV YIIIDNPENK NSILDIQHVE VNADGSVKIN SYLDSFPFPY YVIVRDLNQL
PLVLSEAMRQ WFELVNSE
//
