ID B4J9Y1_DROGR Unreviewed; 192 AA.
AC B4J9Y1;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=GH22067 {ECO:0000313|EMBL:EDW02568.1};
GN Name=Dgri\GH22067 {ECO:0000313|EMBL:EDW02568.1};
GN ORFNames=Dgri_GH22067 {ECO:0000313|EMBL:EDW02568.1};
OS Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Hawaiian Drosophila.
OX NCBI_TaxID=7222 {ECO:0000313|Proteomes:UP000001070};
RN [1] {ECO:0000313|EMBL:EDW02568.1, ECO:0000313|Proteomes:UP000001070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15287-2541.00 {ECO:0000313|Proteomes:UP000001070};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH916367; EDW02568.1; -; Genomic_DNA.
DR RefSeq; XP_001987701.1; XM_001987665.1.
DR AlphaFoldDB; B4J9Y1; -.
DR STRING; 7222.B4J9Y1; -.
DR EnsemblMetazoa; FBtr0157481; FBpp0155973; FBgn0129528.
DR EnsemblMetazoa; FBtr0452295; FBpp0402992; FBgn0129528.
DR EnsemblMetazoa; FBtr0456636; FBpp0407181; FBgn0129528.
DR GeneID; 6560749; -.
DR KEGG; dgr:6560749; -.
DR eggNOG; KOG0393; Eukaryota.
DR HOGENOM; CLU_041217_21_2_1; -.
DR InParanoid; B4J9Y1; -.
DR OMA; MINAFAY; -.
DR OrthoDB; 20499at2759; -.
DR PhylomeDB; B4J9Y1; -.
DR Proteomes; UP000001070; Unassembled WGS sequence.
DR GO; GO:0045179; C:apical cortex; IEA:EnsemblMetazoa.
DR GO; GO:0016324; C:apical plasma membrane; IEA:EnsemblMetazoa.
DR GO; GO:0070451; C:cell hair; IEA:EnsemblMetazoa.
DR GO; GO:0044291; C:cell-cell contact zone; IEA:EnsemblMetazoa.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:EnsemblMetazoa.
DR GO; GO:0019900; F:kinase binding; IEA:EnsemblMetazoa.
DR GO; GO:0051017; P:actin filament bundle assembly; IEA:EnsemblMetazoa.
DR GO; GO:0070252; P:actin-mediated cell contraction; IEA:EnsemblMetazoa.
DR GO; GO:0034334; P:adherens junction maintenance; IEA:EnsemblMetazoa.
DR GO; GO:0007298; P:border follicle cell migration; IEA:EnsemblMetazoa.
DR GO; GO:0090254; P:cell elongation involved in imaginal disc-derived wing morphogenesis; IEA:EnsemblMetazoa.
DR GO; GO:0007349; P:cellularization; IEA:EnsemblMetazoa.
DR GO; GO:0001745; P:compound eye morphogenesis; IEA:EnsemblMetazoa.
DR GO; GO:0070593; P:dendrite self-avoidance; IEA:EnsemblMetazoa.
DR GO; GO:0007368; P:determination of left/right symmetry; IEA:EnsemblMetazoa.
DR GO; GO:0046663; P:dorsal closure, leading edge cell differentiation; IEA:EnsemblMetazoa.
DR GO; GO:0007395; P:dorsal closure, spreading of leading edge cells; IEA:EnsemblMetazoa.
DR GO; GO:0032456; P:endocytic recycling; IEA:EnsemblMetazoa.
DR GO; GO:0006897; P:endocytosis; IEA:EnsemblMetazoa.
DR GO; GO:0042249; P:establishment of planar polarity of embryonic epithelium; IEA:EnsemblMetazoa.
DR GO; GO:0045184; P:establishment of protein localization; IEA:EnsemblMetazoa.
DR GO; GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IEA:EnsemblMetazoa.
DR GO; GO:0007377; P:germ-band extension; IEA:EnsemblMetazoa.
DR GO; GO:0008347; P:glial cell migration; IEA:EnsemblMetazoa.
DR GO; GO:0035099; P:hemocyte migration; IEA:EnsemblMetazoa.
DR GO; GO:0007480; P:imaginal disc-derived leg morphogenesis; IEA:EnsemblMetazoa.
DR GO; GO:0035317; P:imaginal disc-derived wing hair organization; IEA:EnsemblMetazoa.
DR GO; GO:0035149; P:lumen formation, open tracheal system; IEA:EnsemblMetazoa.
DR GO; GO:0045199; P:maintenance of epithelial cell apical/basal polarity; IEA:EnsemblMetazoa.
DR GO; GO:0035006; P:melanization defense response; IEA:EnsemblMetazoa.
DR GO; GO:1903475; P:mitotic actomyosin contractile ring assembly; IEA:EnsemblMetazoa.
DR GO; GO:0008045; P:motor neuron axon guidance; IEA:EnsemblMetazoa.
DR GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:EnsemblMetazoa.
DR GO; GO:0007405; P:neuroblast proliferation; IEA:EnsemblMetazoa.
DR GO; GO:0007422; P:peripheral nervous system development; IEA:EnsemblMetazoa.
DR GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IEA:EnsemblMetazoa.
DR GO; GO:0090303; P:positive regulation of wound healing; IEA:EnsemblMetazoa.
DR GO; GO:0007374; P:posterior midgut invagination; IEA:EnsemblMetazoa.
DR GO; GO:0090251; P:protein localization involved in establishment of planar polarity; IEA:EnsemblMetazoa.
DR GO; GO:0071896; P:protein localization to adherens junction; IEA:EnsemblMetazoa.
DR GO; GO:0030589; P:pseudocleavage involved in syncytial blastoderm formation; IEA:EnsemblMetazoa.
DR GO; GO:0110020; P:regulation of actomyosin structure organization; IEA:EnsemblMetazoa.
DR GO; GO:0050770; P:regulation of axonogenesis; IEA:EnsemblMetazoa.
DR GO; GO:0030334; P:regulation of cell migration; IEA:EnsemblMetazoa.
DR GO; GO:0016476; P:regulation of embryonic cell shape; IEA:EnsemblMetazoa.
DR GO; GO:0051489; P:regulation of filopodium assembly; IEA:EnsemblMetazoa.
DR GO; GO:1904059; P:regulation of locomotor rhythm; IEA:EnsemblMetazoa.
DR GO; GO:0035298; P:regulation of Malpighian tubule size; IEA:EnsemblMetazoa.
DR GO; GO:1901739; P:regulation of myoblast fusion; IEA:EnsemblMetazoa.
DR GO; GO:0035159; P:regulation of tube length, open tracheal system; IEA:EnsemblMetazoa.
DR GO; GO:0007435; P:salivary gland morphogenesis; IEA:EnsemblMetazoa.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR GO; GO:0035277; P:spiracle morphogenesis, open tracheal system; IEA:EnsemblMetazoa.
DR GO; GO:0035202; P:tracheal pit formation in open tracheal system; IEA:EnsemblMetazoa.
DR GO; GO:0007370; P:ventral furrow formation; IEA:EnsemblMetazoa.
DR GO; GO:0042060; P:wound healing; IEA:EnsemblMetazoa.
DR CDD; cd01870; RhoA_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR InterPro; IPR003578; Small_GTPase_Rho.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR24072:SF168; RAS-LIKE GTP-BINDING PROTEIN RHO1; 1.
DR PANTHER; PTHR24072; RHO FAMILY GTPASE; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Reference proteome {ECO:0000313|Proteomes:UP000001070}.
SQ SEQUENCE 192 AA; 21705 MW; 188D7D88592183CE CRC64;
MTTIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYVADIEVDG KQVELALWDT
AGQEDYDRLR PLSYPDTDVI LMCFSVDSPD SLENIPEKWT PEVKHFCPNV PIILVGNKKD
LRNDPNTIRD LAKMKQEPVK PQEGRAMAEK INAFAYLECS AKSKEGVREV FETATRAALQ
VKKRKKPKCL LL
//
