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Database: UniProt
Entry: B4JAQ8_DROGR
LinkDB: B4JAQ8_DROGR
Original site: B4JAQ8_DROGR 
ID   B4JAQ8_DROGR            Unreviewed;       810 AA.
AC   B4JAQ8;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   16-OCT-2019, entry version 72.
DE   SubName: Full=GH11475 {ECO:0000313|EMBL:EDW03866.1};
GN   Name=Dgri\GH11475 {ECO:0000313|EMBL:EDW03866.1};
GN   ORFNames=Dgri_GH11475 {ECO:0000313|EMBL:EDW03866.1};
OS   Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Hawaiian Drosophila.
OX   NCBI_TaxID=7222 {ECO:0000313|Proteomes:UP000001070};
RN   [1] {ECO:0000313|EMBL:EDW03866.1, ECO:0000313|Proteomes:UP000001070}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15287-2541.00 {ECO:0000313|Proteomes:UP000001070};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family.
CC       {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; CH916368; EDW03866.1; -; Genomic_DNA.
DR   RefSeq; XP_001988999.1; XM_001988963.1.
DR   SMR; B4JAQ8; -.
DR   STRING; 7222.FBpp0145381; -.
DR   GeneID; 6562622; -.
DR   KEGG; dgr:Dgri_GH11475; -.
DR   eggNOG; KOG3804; Eukaryota.
DR   eggNOG; ENOG4111K4J; LUCA.
DR   InParanoid; B4JAQ8; -.
DR   KO; K03211; -.
DR   OMA; IESHMMQ; -.
DR   OrthoDB; 827924at2759; -.
DR   PhylomeDB; B4JAQ8; -.
DR   Proteomes; UP000001070; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0001709; P:cell fate determination; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR033077; Pokkuri.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849:SF201; PTHR11849:SF201; 1.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001070};
KW   DNA-binding {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001070}.
FT   DOMAIN       29    113       PNT. {ECO:0000259|PROSITE:PS51433}.
FT   DOMAIN      413    496       ETS. {ECO:0000259|PROSITE:PS50061}.
FT   REGION      129    180       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      199    228       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      249    295       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      310    329       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      341    390       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      585    606       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      740    810       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    133    147       Pro-rich. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    150    180       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    202    228       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    249    270       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    279    295       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    341    372       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    585    604       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    740    799       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   810 AA;  87042 MW;  A2B03DE1557C52B9 CRC64;
     MKMLPVQLSL NPLNPIWSDV IWRCPPPPSS QLAELKTQLP PSLPSDPRLW SRDDVLVFLR
     FCVREFDLPK LDFDLFQMNG KALCLLTRAD FGHRCPGAGD VLHNVLQMLI IESHMMQWHL
     PNSPVTPTGR YPLSPHSHPP TPTWPPMNVP QLLDGNNSGG SNSSAGSINS SNLSSNPFHS
     TSSAAAAAAH MAAHHFMAPN SVTLSPPPSV DSQASSPPQQ GATYQNGSTA ATAAATTIAG
     STTGVATTTA GTVGGVQPMK GISSASSNHS DSDDEYSEPN NHSSSNGNNN CNSNNASNNC
     NKLSALPPAP LSSYGTGSPP GTPIHKDLKP TWTQQMTNSF VNSWSQQQQQ QQQQQQQQQQ
     QQQQQPQKLT LDNTGVGIPP GGGSISAPTT PSYMYKAKRE FFPENSEPNT NGRLLWDFLQ
     QLLNDRNQKY SDLIAWKCRD TGVFKIVDPA GLAKLWGIQK NHLSMNYDKM SRALRYYYRV
     NILRKVQGER HCYQFLRNPT ELKNIKNISL LRQTTPQSGA GAGGGGGVGG VAGAAGAAAV
     NQQAPGSPAA VGNWTQQQQQ QQQSQQQQQQ QQQQQQQQQQ QQQQQQQLQL SPQRPASRNA
     TGPPMSLPTA AAVAAAAAAA AYGPQPPSPL FMQAFHYLSA NAAAVAAAAA PPPNSPATAA
     AAASSSVDKF QFHPLKLENG DNGAMAEDLK PTDLSVSSKT ISTTTATTTA NSNEDCYPLI
     RNADGLTTIK LIRYQEQQQA QAQASADAQQ TTESTPEQSN GSSNASSPKP MDALDQQQLQ
     QQQQQQPHPV PMDSDCNGSE ESAFSRHMHQ
//
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