ID B4JGX8_DROGR Unreviewed; 1292 AA.
AC B4JGX8;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=GH19504 {ECO:0000313|EMBL:EDV93756.1};
GN Name=Dgri\GH19504 {ECO:0000313|EMBL:EDV93756.1};
GN ORFNames=Dgri_GH19504 {ECO:0000313|EMBL:EDV93756.1};
OS Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Hawaiian Drosophila.
OX NCBI_TaxID=7222 {ECO:0000313|Proteomes:UP000001070};
RN [1] {ECO:0000313|EMBL:EDV93756.1, ECO:0000313|Proteomes:UP000001070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15287-2541.00 {ECO:0000313|Proteomes:UP000001070};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH916369; EDV93756.1; -; Genomic_DNA.
DR RefSeq; XP_001990694.1; XM_001990658.1.
DR SMR; B4JGX8; -.
DR STRING; 7222.B4JGX8; -.
DR EnsemblMetazoa; FBtr0468883; FBpp0418997; FBgn0126969.
DR eggNOG; KOG4572; Eukaryota.
DR HOGENOM; CLU_004789_0_0_1; -.
DR InParanoid; B4JGX8; -.
DR OMA; WIMYVEN; -.
DR PhylomeDB; B4JGX8; -.
DR Proteomes; UP000001070; Unassembled WGS sequence.
DR GO; GO:1990316; C:Atg1/ULK1 kinase complex; IEA:EnsemblMetazoa.
DR GO; GO:0000407; C:phagophore assembly site; IEA:EnsemblMetazoa.
DR GO; GO:0000045; P:autophagosome assembly; IEA:InterPro.
DR GO; GO:0009267; P:cellular response to starvation; IEA:EnsemblMetazoa.
DR GO; GO:0061723; P:glycophagy; IEA:EnsemblMetazoa.
DR GO; GO:0060729; P:intestinal epithelial structure maintenance; IEA:EnsemblMetazoa.
DR GO; GO:0035096; P:larval midgut cell programmed cell death; IEA:EnsemblMetazoa.
DR GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:EnsemblMetazoa.
DR GO; GO:0035071; P:salivary gland cell autophagic cell death; IEA:EnsemblMetazoa.
DR CDD; cd17060; Ubl_RB1CC1; 1.
DR InterPro; IPR040040; ATG11.
DR InterPro; IPR019460; Atg11_C.
DR InterPro; IPR045326; ATG17-like_dom.
DR PANTHER; PTHR13222; RB1-INDUCIBLE COILED-COIL; 1.
DR PANTHER; PTHR13222:SF1; RB1-INDUCIBLE COILED-COIL PROTEIN 1; 1.
DR Pfam; PF10377; ATG11; 1.
DR Pfam; PF04108; ATG17_like; 1.
PE 4: Predicted;
KW Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001070}.
FT DOMAIN 123..538
FT /note="Autophagy protein ATG17-like"
FT /evidence="ECO:0000259|Pfam:PF04108"
FT DOMAIN 958..1098
FT /note="Autophagy-related protein 11 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF10377"
FT REGION 242..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1265..1292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 729..783
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 882..946
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 248..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 272..286
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1274..1292
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1292 AA; 145922 MW; 282ECBB44AD07783 CRC64;
MMLYVFHVDV GRMLSFDMTV ALSSVENLKE TIQRLHGLPA ANIVLLVSGG EMLTHSTQVS
CYSAGTDTNP IFMFLTGDER LAPTIASGAS GGGGGASGGS SNDAFDAELQ RQVDNSHRLP
AVLETVRQRS ALAQHMREMG RKEEQLCERL VHEQHLQQQG WSAVVANMED VTSEFSERFH
NFCLAFDRHL EQRESYLELL RNFGDDLKQL ARIPILPALM TLAQADFHGF DELLDNEDVE
QMQRETGESA GEPGSESSVE KSSSSTSPNK KLKMGHELEE QEEQTSSKHQ QQQQHQLNLL
QWISSKGNHT ALQQMCDECV QGLETFSVEI YDKLKLDVQN IIKVAKQTDV KEIKGLSDRL
YRLDELKYKI RKMVQDQREQ ATALQQNESR ALNLRDDSVL PDLCLSHRSQ LQVMLENHLR
IREYCRCIAN AKDELGRNLH TRLRRIVWIE NGMSEFDNRL LFYHRCLRRA ERHISIIEQI
HRAPSTYVAA VTEVVRRKIF SDKFRLWASR LSVDFDRIHG EELQRRRLFN NSFDGHFLNI
LFPGMADMPP TFANEHPELS FDTRLPQLSR SDIELLSIQL PELATQLQLP DMAPVLQFFV
QRNKDIGEQL ELDTDADTDT AAASPVCKQS VSTSSTSLIA GQIARSTATE QLLMLSASTL
TDDNAGSVQR LRDALQAMSK LALQCLAMAR SNLSSLRSEL TTHYQDELQS ELQLLQDKWQ
LLRMQCEQRD QQQQQLQQRD QQQQQLQQLE QLEQLEQLRQ QLIAAEQEKL AAVAQAREEL
IHEHKTELES LRCRFKLMTS MERSPSDSSL EKVERPTSSA SVASLDVEQL LAQQRQDLLA
QRDRAISEAV QAERALWESR QQEQQQQQSL PQLNSESVMV NVSILKDMLE DKERQLDMLR
EQNRLLNQEN YTLKTRFDLL TNEDGNSWLK EKIEYLNRDK NRLEEELCLE KGKRLEMESS
VAAMRSSAFD MAGTLTRSKS SGVAATSSAS SSNHRFITLE GCGKGDLVFV VWSMRHGQYM
VVQDSVTKYF VHADSLAALQ LTPPPPPQLP AAGVLELNQI PLPYYAIGRV IDKEYCQARK
DENRYRVSRG SKFYRIRLSP VSSSRNAPRR ERLESTSSSG AISRSQLVTA VRDVIEAPGS
SLAGSSVYLS FKERTVSISS VNEEEDESAS LLSERCRYIS AQSEPETETT TTTTIPIYEP
NLVSDANPIQ LTDEPVTIYL STTTTTETAA EIAAATTTEA EADTTSDIVV VEPNLCTAAT
LPMSIGASTT NEDSDEYRSL EGKEDADLPI SE
//
