ID B4JNY0_DROGR Unreviewed; 4576 AA.
AC B4JNY0;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=GH24913 {ECO:0000313|EMBL:EDV92423.1};
DE Flags: Fragment;
GN Name=Dgri\GH24913 {ECO:0000313|EMBL:EDV92423.1};
GN ORFNames=Dgri_GH24913 {ECO:0000313|EMBL:EDV92423.1};
OS Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Hawaiian Drosophila.
OX NCBI_TaxID=7222 {ECO:0000313|Proteomes:UP000001070};
RN [1] {ECO:0000313|EMBL:EDV92423.1, ECO:0000313|Proteomes:UP000001070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15287-2541.00 {ECO:0000313|Proteomes:UP000001070};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; CH916371; EDV92423.1; -; Genomic_DNA.
DR RefSeq; XP_001992716.1; XM_001992680.1.
DR SMR; B4JNY0; -.
DR STRING; 7222.B4JNY0; -.
DR EnsemblMetazoa; FBtr0470476; FBpp0420540; FBgn0132368.
DR GeneID; 6565840; -.
DR KEGG; dgr:6565840; -.
DR eggNOG; KOG1215; Eukaryota.
DR HOGENOM; CLU_000085_1_1_1; -.
DR OMA; RTCQPEQ; -.
DR OrthoDB; 2876235at2759; -.
DR PhylomeDB; B4JNY0; -.
DR Proteomes; UP000001070; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00112; LDLa; 31.
DR Gene3D; 2.10.25.10; Laminin; 8.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 34.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 8.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR22722; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED; 1.
DR PANTHER; PTHR22722:SF14; MEGALIN, ISOFORM A; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF07645; EGF_CA; 3.
DR Pfam; PF14670; FXa_inhibition; 1.
DR Pfam; PF00057; Ldl_recept_a; 31.
DR Pfam; PF00058; Ldl_recept_b; 5.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00181; EGF; 23.
DR SMART; SM00179; EGF_CA; 8.
DR SMART; SM00192; LDLa; 34.
DR SMART; SM00135; LY; 37.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF57184; Growth factor receptor domain; 3.
DR SUPFAM; SSF57424; LDL receptor-like module; 31.
DR SUPFAM; SSF63825; YWTD domain; 8.
DR PROSITE; PS00010; ASX_HYDROXYL; 4.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 4.
DR PROSITE; PS01187; EGF_CA; 4.
DR PROSITE; PS01209; LDLRA_1; 20.
DR PROSITE; PS50068; LDLRA_2; 34.
DR PROSITE; PS51120; LDLRB; 12.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000001070};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 4398..4419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 269..307
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REPEAT 484..527
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 673..715
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 803..845
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1458..1500
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1503..1546
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 2140..2183
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 2184..2225
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 2501..2542
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 3057..3098
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REPEAT 3236..3277
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 3324..3367
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 3973..4009
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REPEAT 4160..4203
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 4205..4248
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 4347..4381
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 4533..4576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4533..4554
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4556..4576
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 38..53
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 89..104
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 129..144
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 149..161
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 156..174
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 168..183
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 273..283
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 971..989
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1004..1016
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1011..1029
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1023..1038
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1043..1055
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1050..1068
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1103..1118
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1143..1158
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1187..1202
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1207..1219
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1214..1232
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2636..2648
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2643..2661
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2677..2689
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2684..2702
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2696..2711
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2716..2728
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2723..2741
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2802..2814
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2809..2827
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2845..2857
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2852..2870
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2938..2950
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2945..2963
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2980..2992
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2987..3005
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2999..3014
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3021..3033
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3028..3046
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3515..3527
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3522..3540
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3534..3549
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3603..3621
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3687..3705
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3723..3735
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3730..3748
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3742..3757
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3762..3774
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3769..3787
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3781..3796
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3806..3818
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3813..3831
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3855..3873
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3900..3918
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3912..3927
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 4371..4380
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDV92423.1"
SQ SEQUENCE 4576 AA; 509914 MW; CD4061CF8AA239F3 CRC64;
DGEDEMQSCP PPECETPQLN CGQYVFNKTY CIPPHYRCDM IEDCQDKSDE AQCTHRKCQH
TDVFCNAANG AAPAEGRLTG PCVPKEKRCD GYLDCRTGRD EDGCNGVACH LDQFRCANGH
KCIDAALKCN HRNDCGDNSD EQGCNFPPCH HAQFRCTNAL CIPYNFHCDG YHDCADESDE
ANCTAIACPD NKFLCPRGGV NGAPKCILKS QLCDGKRDCE DGSDEETACS IASCPALSCE
FKCGPSLTGG VCYCRPGQSL APDNRTCIDL DECAEWGHCD QLCTNTPGSY TCQCAQGYTL
INESKCIAPD ANNLQLIFAH DRAIMRMFAH DSDPKVLANA TAAAGVAFHY ARNTLYWSDI
KTRKVQSLPL DVLNSAVAPL DQTLPGTWAP VALAVDWVGD KIYVADLVGQ KIDVFELSGH
WHAVVLGSNL TSPADLALDP TAGLMFVADG GQVLRAHMDG THARSIVSEA AYKASGVTVD
IIGKRVFWCD SLLDYIESVD YEGGQRVMVL RGQQVPSPSR LALFENRIYW TDATKQGIMS
VDKYEGPSSI QVTYKAKDIR EPKGIIAVHA LSQPHVSNPC GHTNGGCNHM CIVTAVKGAP
TGLGFRCACH TGYQLQTDLK NCKLVREFLM YSQQRFIKGK VLEPVIEGFS DAILPVVSRR
ARFVGLDFDA RDEFIYYSDV LQDVIYRVHR NGTGREIVLA SQNEGVEGLA VDWASKNLYY
IDSRKGTLNV LSTRNVTHRR TLLKNLKRPR AIVVHPNRGY IFFSEWDRPA NITRANTDGT
GLLVFRNVTL GWPNGLSIDF KEDRVYWCDA LLDHVQHANL DGTDIKTVNS RLVRHPFSIV
IHNDWMYITD WRLDAIIRLH KLTGEQEEMM VREPQTNRLY GVKVYSRDVQ RIAETQPCHL
YNGGCQKICF AIPISQNTSE MTTTAGAASR LQSRCSCPYG ERLADDQISC IPDPSAEPPV
QPCPNLWDFT CNNQRCIPKS WVCDGDDDCL DNSDEEQNCT KPTCGSNEFQ CKSGRCIPLN
FRCDQENDCG DNSDEVDCGN VTCATSQFAC ANGRCIPSMW KCDSENDCGD SSDEGDFCAE
KTCAYFQFTC PRTGHCIPQS WVCDGDDDCF DRQDEKDCPP ISCLANQFKC ADLRQCVEES
YKCDGIPDCN DGSDELGCPS MGPNQCNLEK HFRCKSTGFC IPIAWHCDGS NDCSDHSDEE
DCGQITCAQN FFKCNNTNCV FKAYICDGKD DCGDNSDEGT EHACVPPPFK CPHGQWQCPG
VAERCVNITS VCDDTMDCPN GADEGEGCDL AECAHQTGQC SSFCQKTPSG ALCVCPPGSE
IGQDGFTCVD TNECDPPGLC SQECTNTKGS YFCSCTPGYV LGPNKHTCKA VNHTAAFLII
SNRHSILVAD LKEQGLERVP IIVENVVATA SNMHTGTIFW SDMKLKKISR LDHGMEPQEI
INTGLDLVEG LAYDWIAKNL YWLDSKLNTI EVSAENGSNR LVLVRENITQ PRGMCIDPSP
EARFIFWTDW GENPRVERIG MDGTMRKTII NTKIYWPNGL TLDIATKRVY FADSKLDFID
FCYYNGTGRQ QVLASSHYLL HPHSLSLFED TLYWTDRQLN RVLSANKFRG KNQTVVSHLI
SQPLSIHVHH ASLQPMYPNP CAQARCQHLC LLSPSASEGY SCKCKPGYRL LSEGRCIEEE
NPYLMVVKGT QIVDLPLNGG DARAGALAPV IGIESSTGLD FDRKGETLYW VQGREDDDEN
CTIFTTPYGG GNKTLFLDID TGIVGAPYTI AFDWLGRNLY IGNRVASNIE AVRVDGKQKY
RTVILANDGS ENSVSKPKQL VLDPSEGKLF WIDEGVLEVP VKIARVDMNG QDARVLRKDL
KHPESIALDI EKKMIYYSTS HSASICSMDY NGEDHTIILN EDQAISRPRS LGVLDHRLYY
LDPVYEKIVR VDLPRGDNPK TIVDNEPDLR SMMIYKKRAL MQHPCQTGNG GCKQLCIPGA
AASRTCACGI GYHKENEINC VAYKTFAVVS QLDMIRGYSL TDSSEAMVPV SGQGHHILHV
DVMFRDQWIY WAEFNRGYWN GIFRSRPNGT DVQHVVKDGI GSNGIRGLTI DWVAGNMYFT
NVYPHENYVE VCWLDGSNRK VLVKTTNDAP RELAVNPIKR LLYWIDYGQH PRIGKAMLDG
SKWQPLVTSG ISLPRDLTID MQTHDVFWVD SKLDTIQKIS YNGVNRKVIR RDLPNPMGIA
IFRNDVYWVD RNLMTVFKAS KLFGNDTEVT RVRTNLEKLR DIAIYDINNQ PADDNNPCAQ
LGNGGCDQLC FSFPPEPSTA KNYRCDCATG KLGADNHTCE TVNEYLVFAT RTEIRAVNLN
PHSTEVPFTP LSNLTNVVGV DFDFAGNRML YTQIRPWAKI AYTQANKPSH SDITVVLNKG
INPEGIAYDW TQSKIYWTDS SNNSIYAMNL VGTELVMIAR VERPRAIVLD PCNGTLFFTD
WGRFGTSGKI FRTTMAGSLK RAIVDKELSQ PSGLAIDYDD RKLYWTDAVR EKIERADLDG
RNRELLVAAT IYPFAITVFR NYIYWTDVQL RGVYRAEKHT GANMVEMVKR LEDSPRDIRI
FSSDRQKCNV NPCRINNGGC AQSCHPAPNG KAECKCDENS KVVNEGRMCA PRNNTCESSK
FYCQNGKCIS RMWSCDGDDD CGDNSDEELN YCAYHSCSPN EFRCNNGRCI FKSWKCDHEN
DCKDGSDELN CSYPPCVDGE FTCANGRCIP QAQVCNGVND CKDNATSDET HERCPMNTTC
PPNHLKCEKT NICVEPYWLC DGDNDCGDNS DEDPLHCGQR TCPTNSFRCP NHRCIPATWY
CDGDDDCGDG ADEPPDYCKS EGRTCFGDLF TCDNGNCIPR IYICDGDNDC LDNSDEDNRH
QCNDRKCDEE TEFTCVENKS WQRAQCIPKK WICDGDPDCV DGADENTTLH NCATQQPCGE
DMFTCGNGRC INKGWICDHD NDCGDGTDEG KFCNSKYKTC SPLEFTCQNF KCIRNQYRCD
GEDDCGDHSD EVNCKKENVT CAHGQFACTN GQCIDYSLVC NKVADCTDES DEPAHCNVDE
CAKVEINQCG HKCVDTLTGY YCDCNEGYKL LADGKACADV DECLEQPGAC SQHCSNTPGS
FYCKCDETYY ERQNDEHTCK RKDNIPPWLI FTNKYYVRNM SVDGHQYNLM HQDLMNVVAL
DFDIKDQYMY FCDVTAKTIF RAKYSDASVD LPTEREAVIR HDSHGLEGIA IDWVGRKLYW
LDRHSKNLDV SELDGTKRKT LRSGVVDPRA IVVHPGIGYL YFTSWHLQAY IAKMGMDGSN
FTRILNWNDG IAWPNALSID YFTDRIYWAD AHLDYIAYTD LEGRHRHIVL SGNSVPHVFA
LSLFDDFIYW SDWNLKAIVR ANKFHGANYT VLRNTTHRPY DLHINHPLRQ LPYTNPCGTN
NGGCSHLCLI APPPESTYLN IEGYIEEGAP IFKCACPNQF YLARDSKTCI ANCTAGQHLC
GGSDEKCIPW FWKCDGEKDC KDGSDEPSTC TPRHCRAGTF QCKNTNCTPS ATICDGVDDC
GDGSDEQNCE LPCPLSDFKC KTSGRCILDS WRCDGDADCK DGSDEDPLVC HKRSCDPDTE
FSCKNGRCIP QLWMCDFDND CGDDSDEPAY MCRQRNCTTG WQRCPGQSNY RCIPKWLFCD
GKDDCRDNSD ELPDNCPKCS AETDFKCGNN RCIPKQWMCD FADDCGDASD ENDAICKGRY
RECSESEFRC GNGKCISSRW QCDHEDDCGD NSDEMNCEGY QCKNGTFQCA SGHCIASYFR
CDGDRDCRDM SDEVGCPPRF PGGRFCPESR FQCTNNLCVS LTDLCDGTDD CGDGSDEDPK
VCSDFNCDTL RRFQCANHRC VARYQICDGI DNCGDGSDEN NMTLCASKQK PCDLYTQYQC
ANKHCIERAQ VCDFSDDCGD ASDELGCHHT SSCSEQNRGG CQHHCHNLTD GGYICTCYPG
YIIAPDNKKR CADVDECATR QHTCSHQCHN MNGTYSCSCR DGFHLSDGSS GVCKAEKDDV
ILVFANGPEI RGLDLQKKEE FDVIAAEKRI EALDYDAQQQ IVFWADSYDK TIKRSYMVNA
ADGQAKIGFA QDLNMKGGSK PTAVAVDWLA SNLYWTEVDR TGSKPRGRVM VAKTDGRYRR
SIVNAGLEVP TSIAVNPQLG RIYWADAGSA PKIEVSWMDG SKRRPLITEQ IRHPAGLTID
YAQDHIIYWV DTKLNAIESM RADGSRRKAI VKGDQLRHPV SLDLFESNMF WVTRDTGELL
RQDKFGRGVQ VVVHRNLVNP SGLKVYHEKR YNTSLRNPCH ESSCSHLCLL VPGGHRCACP
DTSGPLPSHR STAEVICDAA AERPRPSPRI CPCQNTGLCK EDDRGELYCD CPPDFKGDHC
ERSTTGAFGH GGANVTAVVV PIMVILLVMM AAAGAWYVIR KRPFGKLARM PAITSSQSVT
FRHGSNVEFS ESGFPGASAP GANDMAPIEG YNLQTVNANK ARDFANPMYD AVQSGTNTDP
GMSNGSGIYD VPQEPSKSKA MGHSGSFTEP ASAIIAPSSI THKSSPQLQL RTRELDPSAD
TGKDTQYLVE EDKSEC
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