ID B4KY88_DROMO Unreviewed; 857 AA.
AC B4KY88;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=Patj {ECO:0008006|Google:ProtNLM};
GN Name=Dmoj\GI12519 {ECO:0000313|EMBL:EDW17667.1};
GN ORFNames=Dmoj_GI12519 {ECO:0000313|EMBL:EDW17667.1};
OS Drosophila mojavensis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7230 {ECO:0000313|EMBL:EDW17667.1, ECO:0000313|Proteomes:UP000009192};
RN [1] {ECO:0000313|EMBL:EDW17667.1, ECO:0000313|Proteomes:UP000009192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15081-1352.22 {ECO:0000313|Proteomes:UP000009192};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH933809; EDW17667.1; -; Genomic_DNA.
DR RefSeq; XP_002007191.1; XM_002007155.2.
DR AlphaFoldDB; B4KY88; -.
DR SMR; B4KY88; -.
DR EnsemblMetazoa; FBtr0163244; FBpp0161736; FBgn0135276.
DR GeneID; 6581462; -.
DR KEGG; dmo:Dmoj_GI12519; -.
DR eggNOG; KOG3528; Eukaryota.
DR HOGENOM; CLU_006771_1_0_1; -.
DR InParanoid; B4KY88; -.
DR OMA; KPDIIME; -.
DR OrthoDB; 2911488at2759; -.
DR PhylomeDB; B4KY88; -.
DR Proteomes; UP000009192; Unassembled WGS sequence.
DR GO; GO:0005912; C:adherens junction; IEA:EnsemblMetazoa.
DR GO; GO:0016324; C:apical plasma membrane; IEA:EnsemblMetazoa.
DR GO; GO:0016327; C:apicolateral plasma membrane; IEA:EnsemblMetazoa.
DR GO; GO:0035003; C:subapical complex; IEA:EnsemblMetazoa.
DR GO; GO:0032033; F:myosin II light chain binding; IEA:EnsemblMetazoa.
DR GO; GO:0005080; F:protein kinase C binding; IEA:EnsemblMetazoa.
DR GO; GO:0034334; P:adherens junction maintenance; IEA:EnsemblMetazoa.
DR GO; GO:0001736; P:establishment of planar polarity; IEA:EnsemblMetazoa.
DR GO; GO:0035088; P:establishment or maintenance of apical/basal cell polarity; IEA:EnsemblMetazoa.
DR GO; GO:0016334; P:establishment or maintenance of polarity of follicular epithelium; IEA:EnsemblMetazoa.
DR GO; GO:0035509; P:negative regulation of myosin-light-chain-phosphatase activity; IEA:EnsemblMetazoa.
DR GO; GO:0045494; P:photoreceptor cell maintenance; IEA:EnsemblMetazoa.
DR GO; GO:0008594; P:photoreceptor cell morphogenesis; IEA:EnsemblMetazoa.
DR GO; GO:0035209; P:pupal development; IEA:EnsemblMetazoa.
DR CDD; cd00992; PDZ_signaling; 4.
DR Gene3D; 2.30.42.10; -; 4.
DR Gene3D; 1.10.287.650; L27 domain; 1.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR19964; MULTIPLE PDZ DOMAIN PROTEIN; 1.
DR PANTHER; PTHR19964:SF44; PATJ HOMOLOG; 1.
DR Pfam; PF00595; PDZ; 4.
DR SMART; SM00569; L27; 1.
DR SMART; SM00228; PDZ; 4.
DR SUPFAM; SSF50156; PDZ domain-like; 4.
DR PROSITE; PS51022; L27; 1.
DR PROSITE; PS50106; PDZ; 4.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000009192}.
FT DOMAIN 3..67
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 140..220
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 309..394
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 549..638
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 718..796
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 97..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 812..857
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..435
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 812..832
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 857 AA; 91510 MW; B199E0C6E44A9B60 CRC64;
MHLSADISSA LQQIEAVKKG IDESEDAKLQ MQTADSLNTI MGILTDPVFR TIAHVQESLY
ELGIQLGQHP SMLPNDFDID VSGNLVLSLN GGDVMYDSSA PASPDKSSST GGDVEQRPQS
QNSKSAAADL YATDYAQIQA IELVNDGTGL GFGIIGARNS GVIVKTILPG GVADRDGRLR
SGDHILQIGD VNLHEMVSEQ VAAVLRQSGT HVRLVVVRPI EQNLPTPQYA LEPGSAVVPT
RVLSDPAELE RYLISTGYPE IFGESSTAST PQTTTEDERF VYRGETSMLI DPSIDLDELL
ALPETEKLQV ELKKDANGLG ITIAGYVCEK EELSGIFVKS VSPGSAADLS GRIRVNDRII
EVDGQSLQGY SNHQAVELLK KSGQVVNLRL ERYLRGPKYE QLQQAIAANA NEKLPTSSPG
TPSRAPLPPP PATPSSTTVS REAEDETLPA PEAFMMTTPP SSSLATTTTL SSFGAGKQLL
AVRDSLEGAS KIVATDVVAD KQEAAVHAKN SSLITRHKYY MEPELTEEVE AEIVRKWQKI
VGNDMEVIVA QIKKFAVGGL GISLEGTVDV EGGREVRPHH YIRSILPDGP VGVNGVLRSG
DELLEVNGER LLGMNHLEVV AILKELPLDV RMVCGRSKVT SLLPFSDDTL KKLSNNFENL
LPATDRLVKA KSDGSLATAG SVADADSVAV AAASFNKLKS RSLEPLTGLA MWSSQPQIIE
LVKGDRGLGF SILDYQDPLD SNDTLIVIRS LVPGGVAQLD GRLIPGDRLL FVNSINLENA
SLDQAVQALK GAPKGVVRIG VAKPLPMTDN SLKACSNAST TSEETLDAQQ SPPALPTAAP
PTAVKGAEPD LIPDWRK
//
