ID B4L8V3_DROMO Unreviewed; 1516 AA.
AC B4L8V3;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 2.
DT 24-JAN-2024, entry version 71.
DE SubName: Full=Uncharacterized protein, isoform D {ECO:0000313|EMBL:EDW17128.2};
GN Name=Dmoj\GI16720 {ECO:0000313|EMBL:EDW17128.2};
GN ORFNames=Dmoj_GI16720 {ECO:0000313|EMBL:EDW17128.2};
OS Drosophila mojavensis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7230 {ECO:0000313|EMBL:EDW17128.2, ECO:0000313|Proteomes:UP000009192};
RN [1] {ECO:0000313|EMBL:EDW17128.2, ECO:0000313|Proteomes:UP000009192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15081-1352.22 {ECO:0000313|Proteomes:UP000009192};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH933816; EDW17128.2; -; Genomic_DNA.
DR RefSeq; XP_002011997.2; XM_002011961.2.
DR EnsemblMetazoa; FBtr0424576; FBpp0382414; FBgn0139468.
DR GeneID; 6586382; -.
DR eggNOG; KOG3572; Eukaryota.
DR HOGENOM; CLU_004411_0_0_1; -.
DR OrthoDB; 946033at2759; -.
DR Proteomes; UP000009192; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR InterPro; IPR045838; DEPDC5_CTD.
DR InterPro; IPR027244; IML1.
DR InterPro; IPR048255; IML1_N.
DR PANTHER; PTHR13179; DEP DOMAIN CONTAINING PROTEIN 5; 1.
DR PANTHER; PTHR13179:SF8; GATOR COMPLEX PROTEIN DEPDC5; 1.
DR Pfam; PF19418; DEPDC5_CTD; 1.
DR Pfam; PF12257; IML1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009192}.
FT DOMAIN 101..388
FT /note="Vacuolar membrane-associated protein Iml1 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF12257"
FT DOMAIN 1242..1482
FT /note="DEPDC5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19418"
FT REGION 995..1082
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1003..1044
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1516 AA; 173420 MW; E79E2F6BB83D4593 CRC64;
MKLYKLNTHT RGCNKSYESD LVLNPQDHPT AKVGDVVEIY APDDENGTHL LLQITELNEQ
SKTGRNVISI ESGIATAFKM RSYSNVVMRI VNPADVALDS IEITFKEQYM GRSEMWRLKT
YLTNTCVYAN KKIDYNDMQI RCQVYEMWSQ GERVASGVIT EETKIVFRSS TSMVYLFLQM
SSEMWDFDIH GDLYFEKAVN GFLTELFQKW KKLSCNHEVT IVLFSRTFYA AKSLDEFPAH
MRDCLQQDYK GRYYEDFYRV AIQNERNDDW CTVLAQLRKL FTSYQETVLR YHERQNMVIP
QATNSTATQG NFLEVLNISL NTFEKHYLDR TFDRTGQLSV VITPGVGVFS VDRELTNITK
QRIIDNGVGS DLVCVGEQPL HAVPLLKFHN KDTSITSADD YSLPHWINLS FYSTNKKIAY
SSFIPRIKLP ILSAVDEGDV EENERNFLSC NQSEYIYNSL FDYDAYDEQI FQPLPAQSTC
SLQRVVRAKK TSVPSFETYA YRNNDWENLT PTKIPSLRRK MSDPDIHHGT SGMLATLTDT
ANNLSESLAS EKNARRAIVS IAPIVRPGRA LINPFDPSHV TIKLTSNRRR WTHIFPKGPT
GVLIQQHHYQ AVPAKALPAV NCNRQLQHCN SNSNNSYNNN NNNNEFSSAA TEHFDELSNH
SLLSQTKSFS SQSEEKSDFF KRRNTSLLNA AHAANVPNLT ATQAKSFLWG ATGEQEWTPA
ITTGVDWKSL SIPACLPITT DYFPDKRSLH NDYVISDYTL LPDDVNLDYA KSRAVYRKPL
STEEVCKEIV SQRLAQGFQL IVFEEKQPSS NSCCSTNGSC APSANNLGTS AVLPMKPPCE
TNKEYLLSIG RIFHKISLSG SVITVTGYKP RHPYPPINVD YRYRFHAPQH ETYEISGVNF
TTEKLENFSW NHMDLYICTR GDVDYPLMES LKYWRFRMYL LPKDTVVNKI VNCGCQRCDI
FTDAVVDNTR DQIEDFVRLI ENVSKLRRQI CRKARDSPTT NSFTKRRHST SIISRPLNQQ
HDTPTPRITE KNHNLLNSPL QSINVRPKVE PGRISRNLPG TDAATAAPNG TGPRDDQDDG
FPVDIKFSPN ATLTEMFEAM KHPVNGVGFF TQTQSLPSCT FISYDALMWL RARITNGRHP
LDILEAMRTE RMICHASGDW NQPIVPGFVF YYVVQQDKNA KDYAPPLNDY SAFVNEWLEI
ELQGCNFLWY DEPSPSNVPN FLRDTPAPQS WTAYSKSKRV CRKSHLEIDV NQKSDRMEWG
HVKHHTVMQP GFAFELVVEW VTSSGPIVSD LIAGWMRKAI QCGYQLVPVP ADPMAEPFTE
KSDPLRGPIF IPLCVNFLPE GKGLFDEFPE DSRSDRMLFL QEAILARFGF LPCVLEEKSN
QKKDLPKEYQ YVHCTGNMFA LIRCASNKFQ VESPSRQEAN VTRCVYGHTN NTNVPKKVGF
LWSWNHMIPN KKWKALTINN SADGELFQLK MLRDFREFCS NAEQRLANFW AQSQELKRKS
LKFEHNNNNP DEPKII
//
