ID B4LBQ0_DROVI Unreviewed; 844 AA.
AC B4LBQ0;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=NF-X1-type domain-containing protein {ECO:0000259|SMART:SM00438};
GN Name=Dvir\GJ12562 {ECO:0000313|EMBL:EDW68677.1};
GN ORFNames=Dvir_GJ12562 {ECO:0000313|EMBL:EDW68677.1};
OS Drosophila virilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7244 {ECO:0000313|EMBL:EDW68677.1, ECO:0000313|Proteomes:UP000008792};
RN [1] {ECO:0000313|EMBL:EDW68677.1, ECO:0000313|Proteomes:UP000008792}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15010-1051.87 {ECO:0000313|Proteomes:UP000008792};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SIMILARITY: Belongs to the NFX1 family.
CC {ECO:0000256|ARBA:ARBA00007269}.
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DR EMBL; CH940647; EDW68677.1; -; Genomic_DNA.
DR RefSeq; XP_002046335.1; XM_002046299.2.
DR AlphaFoldDB; B4LBQ0; -.
DR STRING; 7244.B4LBQ0; -.
DR EnsemblMetazoa; FBtr0228487; FBpp0226979; FBgn0199802.
DR GeneID; 6624322; -.
DR KEGG; dvi:6624322; -.
DR eggNOG; KOG1952; Eukaryota.
DR HOGENOM; CLU_014224_0_0_1; -.
DR InParanoid; B4LBQ0; -.
DR OMA; KCQSVCH; -.
DR OrthoDB; 1412at2759; -.
DR PhylomeDB; B4LBQ0; -.
DR Proteomes; UP000008792; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06008; NF-X1-zinc-finger; 5.
DR CDD; cd16697; RING-CH-C4HC3_NFXL1; 1.
DR InterPro; IPR034078; NFX1_fam.
DR InterPro; IPR000967; Znf_NFX1.
DR PANTHER; PTHR12360:SF1; NF-X1-TYPE ZINC FINGER PROTEIN NFXL1; 1.
DR PANTHER; PTHR12360; NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1; 1.
DR Pfam; PF01422; zf-NF-X1; 10.
DR SMART; SM00438; ZnF_NFX; 11.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008792};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT TRANSMEM 822..842
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 197..215
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 250..278
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 304..325
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 358..377
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 385..406
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 410..429
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 437..456
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 493..511
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 597..626
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 636..654
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 706..727
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT COILED 761..796
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 844 AA; 94347 MW; 61D561F0DFE6D7A5 CRC64;
MEKFNKAQAK NLAAAQKLVN AYASSSEDEG ELDEKHILDL LYKHYQASTE APSRDNVNRT
ATFLENTLHS GAATCLICIG SIRRVESIWS CRSCYCFFHL NCIQRWANDS VMQLKVKAEQ
QQQQQTGHYN HLGEYVPPKR PKSLYWCCPQ CRRDYQPADR PTQYECFCGK ELNPQPQPFL
VPHSCGEICA KLLQPKCGHD CKLLCHPGPC PPCAQLAQSS CLCGKSPKRS VRCIDKNWQC
QQKCQALLSC GKHKCNQRCH RPGQCPPCSS KSSQPCECKR EEKVVNCAEP KWKCNNICGA
AFACGLHTCD KVCHAGPCGG GECPLGVRSC PCGKSTRTGD CSQLAETCGD TCQKLLSCGK
HSCAQRCHRG ACNLCLVRTK KKCRCGLHEK ELPCSKEFNC ETKCKQMRDC GKHACNRKCC
GDQCPPCEKI CGKQLSCNKH KCQSVCHNGP CYPCKLESQV NCRCGKTRRS VPCGREKSAR
IVCQELCRIT SKCHHAIKHR CHKGECPPCV QPCGLPNDTS GCGHICKARC HAALRVPKPA
DAPRAQQHKY EYRSLPHPRC EEGVRVACIG GHELATWPCW NSKPTSCQRK CARQLKCGNH
RCQLVCHAVP QPEDMNQQAG CANCEEGCAI PRPPGCTHAC TKGCHAPPCA PCSFVIKSKC
HCGLNQVMYK CSEYFNQEEG GSVQQTLERR QKFGSCGNRC LKNFECGHRC ITVCHPGPCP
NPELCRKKVR IYCACKRLKL EIACDKHRAG QTELKCDANC LEELSKAKAT EQQQLERKLK
QEQEKNRLEL EKYEQKFGKR KHKERKALDV QPASYHIDWQ RWGIYALALL AVMGALGVAY
YADS
//
