ID B4LE98_DROVI Unreviewed; 1820 AA.
AC B4LE98;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Uncharacterized protein, isoform A {ECO:0000313|EMBL:EDW69054.1};
DE SubName: Full=Uncharacterized protein, isoform B {ECO:0000313|EMBL:KRF84151.1};
DE SubName: Full=Uncharacterized protein, isoform C {ECO:0000313|EMBL:KRF84152.1};
DE SubName: Full=Uncharacterized protein, isoform D {ECO:0000313|EMBL:KRF84153.1};
DE SubName: Full=Uncharacterized protein, isoform E {ECO:0000313|EMBL:KRF84154.1};
DE SubName: Full=Uncharacterized protein, isoform F {ECO:0000313|EMBL:KRF84155.1};
GN Name=Dvir\GJ13033 {ECO:0000313|EMBL:EDW69054.1};
GN ORFNames=Dvir_GJ13033 {ECO:0000313|EMBL:EDW69054.1};
OS Drosophila virilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7244 {ECO:0000313|EMBL:EDW69054.1, ECO:0000313|Proteomes:UP000008792};
RN [1] {ECO:0000313|EMBL:EDW69054.1, ECO:0000313|Proteomes:UP000008792}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSC#15010-1051.87 {ECO:0000313|EMBL:EDW69054.1}, and Tucson
RC 15010-1051.87 {ECO:0000313|Proteomes:UP000008792};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
RN [2] {ECO:0000313|EMBL:EDW69054.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TSC#15010-1051.87 {ECO:0000313|EMBL:EDW69054.1};
RX PubMed=18057021; DOI=10.1093/bioinformatics/btm542;
RA Zimin A.V., Smith D.R., Sutton G., Yorke J.A.;
RT "Assembly reconciliation.";
RL Bioinformatics 24:42-45(2008).
RN [3] {ECO:0000313|EMBL:EDW69054.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TSC#15010-1051.87 {ECO:0000313|EMBL:EDW69054.1};
RG FlyBase;
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CH940647; EDW69054.1; -; Genomic_DNA.
DR EMBL; CH940647; KRF84151.1; -; Genomic_DNA.
DR EMBL; CH940647; KRF84152.1; -; Genomic_DNA.
DR EMBL; CH940647; KRF84153.1; -; Genomic_DNA.
DR EMBL; CH940647; KRF84154.1; -; Genomic_DNA.
DR EMBL; CH940647; KRF84155.1; -; Genomic_DNA.
DR RefSeq; XP_002046712.1; XM_002046676.2.
DR RefSeq; XP_015031150.1; XM_015175664.1.
DR RefSeq; XP_015031151.1; XM_015175665.1.
DR RefSeq; XP_015031152.1; XM_015175666.1.
DR RefSeq; XP_015031153.1; XM_015175667.1.
DR RefSeq; XP_015031154.1; XM_015175668.1.
DR SMR; B4LE98; -.
DR STRING; 7244.B4LE98; -.
DR EnsemblMetazoa; FBtr0228958; FBpp0227450; FBgn0200267.
DR EnsemblMetazoa; FBtr0434836; FBpp0391865; FBgn0200267.
DR EnsemblMetazoa; FBtr0440680; FBpp0397258; FBgn0200267.
DR EnsemblMetazoa; FBtr0441364; FBpp0397898; FBgn0200267.
DR EnsemblMetazoa; FBtr0441413; FBpp0397943; FBgn0200267.
DR EnsemblMetazoa; FBtr0443130; FBpp0399552; FBgn0200267.
DR GeneID; 6622812; -.
DR KEGG; dvi:6622812; -.
DR eggNOG; KOG3594; Eukaryota.
DR HOGENOM; CLU_001354_0_0_1; -.
DR InParanoid; B4LE98; -.
DR OMA; DDHKPHF; -.
DR OrthoDB; 2961370at2759; -.
DR Proteomes; UP000008792; Unassembled WGS sequence.
DR GO; GO:0016324; C:apical plasma membrane; IEA:EnsemblMetazoa.
DR GO; GO:0005902; C:microvillus; IEA:EnsemblMetazoa.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:EnsemblMetazoa.
DR GO; GO:0016339; P:calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; IEA:EnsemblMetazoa.
DR GO; GO:0044331; P:cell-cell adhesion mediated by cadherin; IEA:EnsemblMetazoa.
DR GO; GO:0046843; P:dorsal appendage formation; IEA:EnsemblMetazoa.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:EnsemblMetazoa.
DR CDD; cd11304; Cadherin_repeat; 14.
DR Gene3D; 2.60.40.60; Cadherins; 14.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR PANTHER; PTHR24028:SF340; CADHERIN 96CB, ISOFORM D-RELATED; 1.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR Pfam; PF00028; Cadherin; 11.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 13.
DR SUPFAM; SSF49313; Cadherin-like; 14.
DR PROSITE; PS00232; CADHERIN_1; 4.
DR PROSITE; PS50268; CADHERIN_2; 13.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008792};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..1820
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014298866"
FT TRANSMEM 1753..1776
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..129
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 130..246
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 247..366
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 367..482
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 483..584
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 585..695
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 709..814
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 815..938
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 946..1053
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1054..1170
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1171..1284
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1287..1394
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1399..1517
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 1820 AA; 200643 MW; EFB41C4557B9C639 CRC64;
MLLPSLMLLL LGSIGAQLLN HAPHFVPGSG DMSRFSLSEH TPVGSPVYQL KGIDPEGGRL
KYSISGPVFS VDRETGVVRL RQELDRETQD TVEVIISITD EGVYGTEPNT VSQRREIPVR
DYNDNQPTFY GRPYTASVSE SLPVGGELIV EPPIIVVDRD EGLNAEVQIK CVQENDICDI
FEVRAVKLGD GNYTARVALK QPLDFESRPS YIMTISASDS ALENRLTSFA TVSINVIDVQ
DQAPVFTNAP YSATVAENTP AGVSILTVKA IDGDVGIPRE IFLSLEDEPF GHFELVAYGN
PKDGTAMLQT TSVPLDRENP DILQNGGVYV FSIRATELID GAIPAEHSIT RVTIVVTDVD
DHRPEFSASH FNVSIAENLA NGMPLPGLSI FVDDRDMGEN SRYQLKLLDV SKAASVFAVS
PTEGQGRTPV VVKVLDASRL DYDNPAQRKF EFDLVASTHG VEQAKARVEV HLLDANDNAP
VFGQQTYRFT AAENLKTDSL IGVVNATDAD SADFGHVQYV LKGFGADNFY VNPETGGIYL
LRPLDYEKQS TYSLTVVAVD GGGRESNANL YVDVLDVNDN HPSFERNEYS RTIREGAAIF
EPQFFVRAHD ADGPSQGNGK VKYAIVSENS IAGNVFRIEP ATGEITLQKA ARSMDTERGE
YELVVSATDF GIPPLTNTTR VLVRVGISGN QRPIFKGHFQ NVENLPIIGP PSYRVSIPEN
AAPGYNVTTV SAHDPDGLDS LLRYRIVGAN DNFQINELSG LITVSPQARI DRDLNMNSFE
IIVNAVDSGT PIPETATTTV YVNVKDINDE KPKFEQNSYA AYVSERTAVG ESVLRVKAID
KDLNSRLEYS MQGAVRATTK AGVSITNRSS YPVQEAFRVD SQSGEIFVNS SLRHDVAAII
IFTVAVRDLN AEVDPEKQVD TTEVTVYVQS FKDKDPVFKN PGWSSSRPVV NIKIKEEMPI
GSALFILQAE DPVTEQPITS FELVEPKELE YFQISERTGE VILKKRLDYE TLAESGSAEF
DLQVRANSAD RQRSTISRVN ITVENVNDNS PIFEQSSYHA TIIENKGHPE RVLQVRAQDK
DAALNARDER LGYHRIIYSL QGEYAMLFEI NNLTGQIIVA RNQTIDRERT PTIRLQVKAE
DSPGKPTDAK QSIVELLIDV LDVNDNAPEF TKKLYSAVIP ENALKMENVL QLNATDADDG
PGGEIRYELV NEGDANGLFS INAQSGLLTT RRNLTGKGRA DAFVLIVRAQ DNGNQVPKQP
TLFTDVEVRI FIGDVSANDG VPFFVAPRVG QMANVTENAA IGAPVFQVIA SDPDDESTPS
GTISYRILPD TPDAEVFAID THTGLITTRE QLDREEKSMY KVLLEVSDNG QPKQSVTRIL
KIEVLDMDDH EPRFAREIDA GPRTMSVKEE QPAGTIVGNF SAIDEDIGEN AAIDYVIIEG
NNEQIFTIER NNNSVAILKT NQAIDRELVE SFTLTIKCLR LGEPAYRYIG DPYDRQDPSH
LRLTIKILDI DDNLPLFENP DATVGIRINV PIDTVITTLR ASDADAEAAP IALSIVNVTF
VPQFYKRSRK LATGNLQTLF TLNNHTGELR TGGSFADYVD GYFLMRVCAN NSAEAKRQTH
SNIKVFVIRD KSLLKFVFAR PPNEIQHNIR PFQEQLQQKL RPLGLELHVL DTQVFTRADM
SLDFTATSSC FQMFRNGAAL SLKEMQKLMN SKELRHELID IYAAYGVSDL ESCSVRRTHT
AALFGNALMS AGAWLVILAA LIGVAALVAL CTACCLKKKF KRHSKRSLQA SLRTPTEHTP
TSYSYSMPAV LYSEPIYGPL
//
