ID B4LW45_DROVI Unreviewed; 899 AA.
AC B4LW45;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE RecName: Full=DDB1- and CUL4-associated factor 15 WD40 repeat-containing domain-containing protein {ECO:0000259|Pfam:PF14939};
GN Name=Dvir\GJ23658 {ECO:0000313|EMBL:EDW66550.1};
GN ORFNames=Dvir_GJ23658 {ECO:0000313|EMBL:EDW66550.1};
OS Drosophila virilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7244 {ECO:0000313|EMBL:EDW66550.1, ECO:0000313|Proteomes:UP000008792};
RN [1] {ECO:0000313|EMBL:EDW66550.1, ECO:0000313|Proteomes:UP000008792}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15010-1051.87 {ECO:0000313|Proteomes:UP000008792};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH940650; EDW66550.1; -; Genomic_DNA.
DR RefSeq; XP_002053030.1; XM_002052994.2.
DR AlphaFoldDB; B4LW45; -.
DR EnsemblMetazoa; FBtr0239583; FBpp0238075; FBgn0210755.
DR GeneID; 6630647; -.
DR KEGG; dvi:6630647; -.
DR eggNOG; ENOG502QQCQ; Eukaryota.
DR HOGENOM; CLU_321128_0_0_1; -.
DR InParanoid; B4LW45; -.
DR OMA; AHFFHNS; -.
DR OrthoDB; 3039086at2759; -.
DR PhylomeDB; B4LW45; -.
DR Proteomes; UP000008792; Unassembled WGS sequence.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20913; DCAF15-CTD; 1.
DR CDD; cd20917; DCAF15-NTD; 1.
DR InterPro; IPR038914; DCAF15.
DR InterPro; IPR047319; DCAF15_C.
DR InterPro; IPR032734; DCAF15_WD40.
DR PANTHER; PTHR28541; DDB1- AND CUL4-ASSOCIATED FACTOR 15; 1.
DR PANTHER; PTHR28541:SF1; DDB1- AND CUL4-ASSOCIATED FACTOR 15; 1.
DR Pfam; PF14939; DCAF15_WD40; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008792}.
FT DOMAIN 72..275
FT /note="DDB1- and CUL4-associated factor 15 WD40 repeat-
FT containing"
FT /evidence="ECO:0000259|Pfam:PF14939"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 495..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..530
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..550
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 899 AA; 101930 MW; 42B7DBC54EA9E3C8 CRC64;
METDYQNYVE SLSGVSSDDD DISTVDSSDE AEEPTNTQTH PSQTQSRTRN LVQMLYDRER
TGFFSGQSRE GQKQKLPYDQ VPNRLKLYLK DVLASNALEG HIFMGLTACG QYMISHRVVC
NDNTSLNHYS FNVGYKYTLY FWLFQPHKKL RYFFSRRLFD DHVVDNLKSV TMTQWKNADQ
QILVVHGAAT EESEESYITY VKVPKLGCLE CRKLCDDGPY SFYNAHCLNC HLTVHTKYSS
TETDPRFEPT INLLCPERIL IISNGFMHML RIDVDTPAVP NSSSLPQQNY SLPCTQQTLL
LPRTPLASEE DRCSVPFTGS EADSEHSVVA RIIADFSDIE TDHTHRANNA INNRDNEIQQ
RSNAEHNSIG YEKLIFSSNC NNGVAASSMT LLETTLPVVI QNVVGTNEST QSRKRNQRIV
TRSYRNGITT IDMQNTSASS SMTDKSNAYE FSEDNEKCEK ISTFRKRRLA DKKYEFSEDN
SENIIPFTKI RSAGRTTFSP STASSSGQRS LHRFSPTTHY FHNSPCASPS SSPHPAQPSH
TPPPPLHLGF RSPPSSSSLM RSPSRNANAA TVAAQIYNQK SPPLSQATQQ MLSYKPVGPL
GALSPLQVSM AKRFEIGGSM SPNAGLSFLS PRRDEQRIVE MPVQGGVMPE KPVCTKKLRR
RYVDEDDATS VITSEEDDCI SPGYHTSLPM EVHGSCYSEM QMISQASFQR LRCSSVVITQ
HSFDLETFTY YVISMICQKH QKIYNVFYDW AYEFISVCPL SQTISCMLMA QFSARDQMPA
TPTNCMYCTG RMGCVFHNRQ YECRILFTWN MESGQWQVLD YGELKEMHEL FSPLKRLGKS
RLTFAQVARQ MAQEMSASLN RLPDYTSHLR VLNSDMKKSK SSICDLDNMV EFHLKRTIN
//
