ID B4MBY9_DROVI Unreviewed; 2020 AA.
AC B4MBY9;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=Rootletin {ECO:0008006|Google:ProtNLM};
GN Name=Dvir\GJ14200 {ECO:0000313|EMBL:EDW58610.1};
GN ORFNames=Dvir_GJ14200 {ECO:0000313|EMBL:EDW58610.1};
OS Drosophila virilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7244 {ECO:0000313|EMBL:EDW58610.1, ECO:0000313|Proteomes:UP000008792};
RN [1] {ECO:0000313|EMBL:EDW58610.1, ECO:0000313|Proteomes:UP000008792}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15010-1051.87 {ECO:0000313|Proteomes:UP000008792};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH940656; EDW58610.1; -; Genomic_DNA.
DR RefSeq; XP_002058642.1; XM_002058606.2.
DR SMR; B4MBY9; -.
DR STRING; 7244.B4MBY9; -.
DR EnsemblMetazoa; FBtr0230125; FBpp0228617; FBgn0201415.
DR GeneID; 6634852; -.
DR KEGG; dvi:6634852; -.
DR eggNOG; ENOG502QQF0; Eukaryota.
DR HOGENOM; CLU_000920_2_0_1; -.
DR InParanoid; B4MBY9; -.
DR OMA; AGIQMDG; -.
DR OrthoDB; 2996539at2759; -.
DR PhylomeDB; B4MBY9; -.
DR Proteomes; UP000008792; Unassembled WGS sequence.
DR GO; GO:0035253; C:ciliary rootlet; IEA:EnsemblMetazoa.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0031223; P:auditory behavior; IEA:EnsemblMetazoa.
DR GO; GO:0032053; P:ciliary basal body organization; IEA:EnsemblMetazoa.
DR GO; GO:0007605; P:sensory perception of sound; IEA:EnsemblMetazoa.
DR GO; GO:0050975; P:sensory perception of touch; IEA:EnsemblMetazoa.
DR PANTHER; PTHR23159:SF54; CENTROSOMAL PROTEIN 135KDA, ISOFORM B-RELATED; 1.
DR PANTHER; PTHR23159; CENTROSOMAL PROTEIN 2; 1.
DR Pfam; PF15035; Rootletin; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008792}.
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1415..1441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1759..1822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1996..2020
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 200..248
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 324..414
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 516..672
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 705..1055
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1081..1213
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1256..1290
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1316..1371
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1451..1653
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1682..1751
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1870..1897
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1928..1955
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 20..61
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1415..1436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1780..1822
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2020 AA; 231100 MW; A2F5FF478740AF84 CRC64;
MQAYRDNFKQ TPCPSAVDPP ALPSSSSARL PFSRNRGRGE PTTSNTINNN NNNTSNVSGG
MLSPAPGPPG TTDALLRQNQ ELRQRLADES HSYRKRLDTY KQAQHNQANL VSRLQSKIQQ
YRQRCSDLEE RMHDTIKPTT TGPCAPKLTT GPTTSQVMCS TSLTLGQSSL PCSSSLDSPP
PSCGRDYLHD DASSELCRKL EEEHNRCEQI VAQNNALRQQ LEESNRTNEA LTNDLQKLTN
DWSSMRDELL IKEDEFKEEE QAFKDYYNSE HNRLLKMWRE VVAVKRAFKD MQTAMKTEVA
KMGQEINGVA KDINCSNSSV AFSLEQAKRA ADEELKQTRR LNDELQAQLA TLKVQHESAR
HEIMERDQRL LELMNQLKKL EDRCAQAEAQ AALANRYNDE IERLNNSMRE IAQAVVQDAE
IADREADAEV NAAMQHMHLT RDAVATNAGG GGGGGKSPRR SSTRASQAFA EGTISAVQAA
LHKYQLALHD MQVKFQQSSE SLRSTRSQLD TSEGTKQLLT GKMQQLTEKL DASNSKLSEL
LQERDSLQKT LDDMRTQKQQ AEMGRADLNN AFENLSGDFE KLQLNYGKLQ KRIDSMEEDK
KAVELEIQRI LKDKNITEMN LRSEEDRSSR LREETISLRE ELNRVSLNRD LLEQQRIESD
NLINLLEKQK CDLEYDLDKL LLDKCELQEK HEKLSSNNSS TSDELKSVQS CLLEAQEERK
KLRHQAADQA SEIGELKKEL AVLDKARLEL ETDNLSYSEK LKCLQLEKEK ILQDLACMTR
EKCDIHNQLT AMCRKKETLN EELMRTRQRL EQTTETNNRL NRNIEDMVKD VEEKQVVIDL
HEKDTHRLNE LLAALRSEKE SLETVLFDTN TTLEAVEEKR SQLERDLQEA LVREESLKNH
VARLQKELEL CQRKAQETKT QLLNAARAAE NDFNQKLANL QAAAEDAAKR HGDEVLQLRN
ALEKRMQQAL QALQTAKDDE IEKLQERLAA LQAHIESLVQ QHEETLIRAE NEKQQALLMA
HRDKQAVAER LETVARDLKT EQEALDRSKR EANARDEKQR AAIAMLKDEI VHMRTRDEEH
KIKLEECIRK QELQLNSMRE ERDTLCRLSE ELKMEIRLRE DKMEATNNEL QDALRKTKEG
EGYIDSLRKE LTDSRRQLAD SNIERDKYSA SNKELRDHVK RVESAKREQA RAIEEALQKI
NNLEETKNSL EIERTRVSTI LKETENNFTK TTQELGAIKS QLQKTQLEFA QKDEGGKELQ
SKLAAETELK ERAQQELGQI KKQLSDLEAN LCATRQELGR ARCHNNQEEH RFHAREQELA
ARMEEARGRE KRLEDQKHNL EVCLADATQQ IQELKARLGG AEGRIRALDE QLACVELHKR
DTEHKLSSVV HTLRRIAGIQ VDGSVNLSHR LLSPSRRFSP SRSVGDYDTR STSQCPDAPV
DVDPDLVRKG VRNLMHQVAQ LEREKDDYKS QLGAARKQLQ DAAEQQLRCD AKLGKLQTIL
RNLQEERSNL ETDRKMKISA LNALEEKLKQ RTDECQMLRE RLAQTEMQLA ATSEENGQNE
ERLEKCRQMC GKLDNEKRTL QEELAKVEGR ASKLDLQRVA MEGDLARLQM ALQEKDCNIR
QVSERLENQN RAMIQLEDRC TSLKSTVDQL KERLQKSAVT ETQLRGEIKT LQKELSEQGH
CSQANEDKLK LLQKSLQTAE NEKRILTERL DSAQTNLNEL RRSQQAQLDG NQRLQEQVTD
LEVQRSALES QLRIAKWNQE SGDKGLTSGN GGGGAGQEEE ELSRQLKSSQ REKSELRSKL
QTLQDKVKQL ESDRKSKFAG GSAYDRAEKA SSYYGGGGGD AGEYDSNRYD LGTGVAYSCG
LDHSVIEQET RDLRLKVRRL ETLLAEKESE LARCKARMHD SAKCSEGLDA DRYRSAQMHA
EKLLDAREQS HKQQVLRLEN QISMLREQLA QEAKRRQQYI LRSSKANREM QHLRSTLGDS
LRNVSQHPVD AHLLESESRR LDSAVSMSLP PSTCRDYDRD
//
