ID B4N8N4_DROWI Unreviewed; 4597 AA.
AC B4N8N4;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 2.
DT 24-JAN-2024, entry version 94.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN Name=Dwil\GK12095 {ECO:0000313|EMBL:EDW81485.2};
GN ORFNames=Dwil_GK12095 {ECO:0000313|EMBL:EDW81485.2};
OS Drosophila willistoni (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7260 {ECO:0000313|EMBL:EDW81485.2, ECO:0000313|Proteomes:UP000007798};
RN [1] {ECO:0000313|EMBL:EDW81485.2, ECO:0000313|Proteomes:UP000007798}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14030-0811.24 {ECO:0000313|Proteomes:UP000007798};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SIMILARITY: Belongs to the dynein heavy chain family.
CC {ECO:0000256|ARBA:ARBA00008887}.
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DR EMBL; CH964232; EDW81485.2; -; Genomic_DNA.
DR RefSeq; XP_002070499.2; XM_002070463.2.
DR SMR; B4N8N4; -.
DR STRING; 7260.B4N8N4; -.
DR EnsemblMetazoa; FBtr0419127; FBpp0377265; FBgn0214106.
DR GeneID; 6647195; -.
DR KEGG; dwi:6647195; -.
DR eggNOG; KOG3595; Eukaryota.
DR HOGENOM; CLU_000038_9_1_1; -.
DR InParanoid; B4N8N4; -.
DR OrthoDB; 166463at2759; -.
DR Proteomes; UP000007798; Unassembled WGS sequence.
DR GO; GO:0005930; C:axoneme; IEA:UniProt.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0036126; C:sperm flagellum; IEA:EnsemblMetazoa.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0030317; P:flagellated sperm motility; IEA:EnsemblMetazoa.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 2.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 6.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF343; DYNEIN AXONEMAL HEAVY CHAIN 10; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08385; DHC_N1; 2.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007798}.
FT DOMAIN 1881..2017
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2160..2292
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2516..2669
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT COILED 3394..3456
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 4597 AA; 528679 MW; 70AB05D0EB2648C6 CRC64;
MPGQEATEFE DAIVRIPVDP KKLDLIPTYT TTQLEDVVSG WMKYLTKTMK TLKDTKLDEF
TPMAEYRYWH KMELELYGTL EQLKTDFVVA VLQRLADDES KILPEWEAVL EKTQERFKLA
KENSDYLGTI TDYLEKIRSY ESFKMTVLQI PNIMVGLRHI WTMSSYFCRD PEMQVLLCQI
SNVFVQKVKN IINFDNIFRY SATYTHETAT NCANLLRCWK QAYKLSRQHI EESGAGSRWE
FDRVALFNEV NHIHRVAVDI AYIGRVFIQY ENLFGHRLKA LIADPSIVDN LMRKVYRMLD
ELIRSVDYDM FLPSNWENWE YSLEQFNRRL EVLEIEAKMV IDQSINSLLS SEKGLQLITN
ASTLDTRQSL QEFVATKHEN LLRYFVTEIN AVETVFLNNR KTPPMAKHQP AKISAICWSR
LLGRKLKKSV LAFKSIEDDP ALANSFLKRT SFKQYFELMA VMFQFEKVLF EKYIQSATYI
INHTNRSNIL GIRICREDTM NAIAEASQTL KAKPRDNLNT AGSRHGVSQM LSLANVQSEG
TMSLAESYNF SEDADTEEDT VDVGDTGPVG FMCRINRFTV LTAMIMWMVS KTRHGNVQLQ
KCIAFLSLIK DRKARDIKAQ DKEHAKICEL LVRAETQRLL PTWRELVGDR VLIEYDMHFV
VNLNREIFDV MFEGQLFEHL GFELPAVLRT AIMKKNLLFN DYEKLTEVIE RYNKIIGNLS
LSEVIFLRDH IYDTELYIQM GVGRYSWISF NIAKFCDQVN SQLRKLTSIV AQINFIRVDL
RNRIEMIKAY NLFNLDDEIQ ESATPSINFR RSRTQSATRG TSSTIRNFVS SGGENITIYQ
AEEEPDEEKK EQQACGTEIY QCQGYFERLE ASRNRKAAQM KKLYDSLGPV LIKLESLVLG
TFTGRSEKMR TYYKFWEEET FKCIVDMTFQ NLKCYINRLL SDSPMFEVNA VLLMSEIVLE
PSVQELQNII VTAAKDYLSR LQIFTRWMAG TCVNCPPIET GTQWKFNYTF YEDIMQNSAI
VELIISIHDL ASKIANEARG FVVQFRKYFN LWAYEKNLIC QKFVERQVTL IEIDEKFTFY
SAIVEDMANM RKYQDVKCVR INLQPLLDSI TQHAQEWCTI LGEELLRHVN ENMRAMRNEI
KTLSMNLNKP TRELEDFKLV MQTVATIQST TLTNEQKIHE MQETFTVLSE HEIMFPYEDM
LMAHHLEKRW KRLFLSALYR SEKLQPIKQK FADMTSVEIE VFYDDLAEFI KDWDENGPGS
VGPELERGVR LMDPYGHKIS EREDRRQELA NAERLFDMPM MDYHEFGRVQ TEFEGLQQIY
KLYKAQKNGR EGWAKTLWAD LDPTVLTEGV ESYLKEFRKL PKPVRQLPVG QQLELHMKQF
KGTVPLMVSL KHEALRERHW LQLMEKTGQH FDMSPARFTL ENMFGMQLHK YQEIAEQILT
NAIKELQIER GVRAVEETWA AMAFKVIKHY KGMEDRGWIL GPVDEIMQQL EDNGMNLQSM
GASQFIGPFL ETVNKWERLL ALISEIIDEW LVVQRKWLYL EGIFIGGDIR TQLPEEARKF
DDIDKAYRRI MVDCAKNPLV VPFCSIPGRL VEIQGLGIGL ENCQKSLNEY LDSKRRIFPR
FYFISTDELL SILGSSEPSA VQNHIIKMYD NIKSLRLVKE GSQTIVTAMI SSEGEVMEFR
HVARAQGRVE HWMNDVLDEM RRSNRFITKT AIYDFGTDLE ISRPDWLMNY QGMVGLAASQ
VWWTAEVEEA FDQAQNHGNM RAMKDFLNKN NYQIEELVLK VRSNLSRNDR LKFKALCTID
VHARDIIDTF VRDNVLDASE FSWESQLRFY WVKFYDNLHV LQCSGSFEYG YEYMGLNGRL
VITPLTDRIY LTITQALLMN LGGAPAGPAG TGKTETVKDL AKAMGLLCVV TNCGEGMDYR
AVGTILSGLV QCGAWGCFDE FNRIDISVLS VISTQLQTIR NGLIRKLERF VFEGVEIKLD
PKCGVFVTMN PGYAGRTELP ESVKALFRPV TCIKPDLELI CLISLFSDGF LTAKVLAKKM
TVLYSLAQAQ LSKQCHYDWG LRSLNSVLRM AGVMKRQSED LPEAVVLMRV LRDMNFPKFI
FEDVPLFLGL IKDLFPGIDC PRIGYPDFNA AVRHVLVNDG YILLPDQEDK VVQMYETMMT
RHSTMIVGPT GGGKTVVINA LVKAQTHMGL PTKCIVLNPK ACSVIELYGY LDMETRDWID
GLFSNIFREM NKPIEREERR YACFDGDVDA LWIENMNSVM DDNKLLTLAN GERIRLENYC
ALLFEVGNLN YASPATVSRA GMVYVDPKNL RYSPYWHRWV LTRPEPQREL LNNFFEKIIT
QAIAFILEGV DGTTQGLPLK MVIMQTDLNM VTQFCNMYDA MLPIYGPSDN KNFDEPVIQV
YNTDTLECCF LQGIYGSLGA CLLEKHQLIF DEFMKRTSGF PQFQDTPESP ARGGQFPQSK
PTLYDYFWDI RDNCWKAWEW VVKPYTHNPD VKFSEILVPT VDNTRTNHLL ALMSEIKRPV
LLVGEAGTSK TATIMQYLRN LNQNVNIILN INFSSRTSSL DVQRTLEAAV EKRTKDTYGP
PMGKKIACFI DDMNMPQVDE YGTQQPIALL KLFFERGGMY DRDKDLNWKK FKDMTFYAAM
GTAGGGRNEV DARFISMFST YNIVFPNDES LVQIYSSIFK GHLEFVSFHN RYMMIADIIV
IMTLKLFKLV IADLPPTPSK FHYIFNLKDL SRIFAGMLLI KPANFKNLRE MIRVWRNEFT
RIICDRLISE TDINTVRRNL SMEVADRFPP EFEELNGFID LDAAAAEAQA RLLYEAYADD
AAAAAAEGEE GEEEEDAGEE GPPVILSLKD YVLRDPLLFG DFRNFTNESE PRLYEDLLDY
SSVFALFTEI LEEYCERRQK MTLVLFEDCL EHLTRVHRTL RMNRGHVLLI GVGGSGKKCI
TRLSSFAAEC EVFEITISRG YNEAAFREDL KALYTLAGVK RKKVVFLFTA AQVAEEGFLE
LINNILTVGQ VPALFADEDK DSIVNQVRKF AEEEGLSASK DSVWAYFLRT CAENLHVVLC
MSPAGDALRN RCRNFPGLIG STYIDWVFPW PKQALYAVAK LFLTEHPMIP ADHRDAIIEH
VVHVHKTIQI YSRDYQAKLR RNNFVTPKHY LDYINTYLGL LEEKHHFITQ QRERLGEGIK
KIEEASVQID ELRLIVTEQK KNVAIASEEC EAMLVTIEAS TQKANIKKVE ASEKSVEVEI
KGKQIAIEKE EAEEILAEAM PALEEARRAL SELDKAQITE IRSFATPPAA VQVVCECVAI
LKGIKEISWK TAKGMMSDVN FLKSLMEMDC EALTQKQISA CRAHMKTQNL DDMGKISIAG
AGLLKFVKAV LGFFDVYREV KPKKERVDFL VEEQEVQIKL LNHLNAEIQK LEEKLEQLNE
NYAVSMKQMK ALVEMMQQAE RRLIAADKLI SGLSSELIRW SKEMASLGQQ LIDSVGVCLI
SSSFLAYTGA FTWEFRKTMV FEDWLEDIKS LGIPINLPFK IDAYLTTDVE ISQWTSEGLP
PDELSVQNGI LTMRASRFPL CIDPQLQALQ WIRKKEYRNN LKILSFSDFD FLKQLEMAIM
YGLPVLFEDV DDYIDPVIDD ILQKNVRVQG GRKFIMLGDK EVDWDPGFRL YLTTKFSNPK
FDPAVYAKAL VINYTVTQTG LEDQLLSVVV GTERPDLEQQ RESLIAQTSE NKQLLQQLED
SLLRELATST GNMLDNVELV ETLENTKSKA GLVMTQLKLA SETAADIEVL RNGYRPAAKR
GAVLFFALSD MSTVNSMYQY ALAAYLDVFI YSLRKAVPDT VLAKRLNNII KTLTENVYCY
GCTGIFERHK LLFSFQIATK LAQRDGVLQQ SELDFFIKGS IALTKSERQN PTKWLPDKCW
EDILKLAFDF PEPFGSLPDH FGRFVTEWKE WYDLENPEAV ACPGDYNINC NAFQKLMFLR
CFRVDRIFRC INQYIVDTMD EFYIMPPVVS FSAIYEQTSC TIPVCFILSA GSDPTNDLIK
LADLVIGGMA NFCHISLGQG QEKAALRLLD NAIRQGQWLM LQNGHLLIKF VRELEKYLDK
IENPHPDFRL WITTDPTPTF PIGILQKSLK VVTEPPNGLK LNLRSTYFKV RQERLECCTH
RGFRPLVYVL AFFHAVVQER RKYDKLGWNI AYDFNDSDFE VCTEILRTYL NRCADDKIPW
NSLKYLIGEV MYGGRVIDDF DRRITNCYMN EYMGDFLFDE FQTFHFYEDD NVDYCLPEDE
TILKEDYIAH IDKLPLVNKP DVFGLHPNAE IGYYTMAARN IWNSLIELQP QTGEGTGGIS
RDDFIDSVAA GILKKLPAAF ETWRIRKQIQ MSLSPTGVVL LQELDRFNLL VIRIKKTLEL
LRKAIAGEIG MDNVLDNIAN SLFNGLLPNA WASLAPATCK QLASWLNHLQ QRAVQYKYWT
LSGEPLVIWL SGLHIPQSYL TALVQIACRK NAWPLDRSTL FTYVTNYADP DDVEERPVTG
CFVHGLYIEG ARFDLATNQL ARSHPKVLVE ELAILAVEPI EAHRLKLQNT FLAPVYTTSL
RRNAMGVGLV FEANLATSED LSHWVLQGVC LTLNTDT
//
