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Database: UniProt
Entry: B4QGN7_DROSI
LinkDB: B4QGN7_DROSI
Original site: B4QGN7_DROSI 
ID   B4QGN7_DROSI            Unreviewed;      1415 AA.
AC   B4QGN7;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   12-SEP-2018, entry version 40.
DE   SubName: Full=GD10124 {ECO:0000313|EMBL:EDX06262.1};
GN   Name=Dsim\GD10124 {ECO:0000313|EMBL:EDX06262.1};
GN   ORFNames=Dsim_GD10124 {ECO:0000313|EMBL:EDX06262.1}, GD10124
GN   {ECO:0000313|FlyBase:FBgn0181899};
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240 {ECO:0000313|EMBL:EDX06262.1, ECO:0000313|Proteomes:UP000000304};
RN   [1] {ECO:0000313|EMBL:EDX06262.1, ECO:0000313|Proteomes:UP000000304}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mixed {ECO:0000313|EMBL:EDX06262.1};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
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DR   EMBL; CM000362; EDX06262.1; -; Genomic_DNA.
DR   FlyBase; FBgn0181899; Dsim\GD10124.
DR   OMA; ANETFCL; -.
DR   OrthoDB; EOG091G03X7; -.
DR   PhylomeDB; B4QGN7; -.
DR   Proteomes; UP000000304; Chromosome 2R.
DR   Bgee; FBgn0181899; Expressed in 4 organ(s), highest expression level in female reproductive system.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd11720; FANCI; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR026171; FANCI.
DR   InterPro; IPR029312; FANCI_HD2.
DR   InterPro; IPR029308; FANCI_S1.
DR   InterPro; IPR029315; FANCI_S2.
DR   InterPro; IPR029313; FANCI_S3.
DR   InterPro; IPR029314; FANCI_S4.
DR   PANTHER; PTHR21818; PTHR21818; 1.
DR   Pfam; PF14680; FANCI_HD2; 1.
DR   Pfam; PF14675; FANCI_S1; 1.
DR   Pfam; PF14676; FANCI_S2; 1.
DR   Pfam; PF14677; FANCI_S3; 1.
DR   Pfam; PF14678; FANCI_S4; 1.
DR   SUPFAM; SSF48371; SSF48371; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000304};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000304}.
FT   DOMAIN       58    277       FANCI_S1. {ECO:0000259|Pfam:PF14675}.
FT   DOMAIN      382    515       FANCI_S2. {ECO:0000259|Pfam:PF14676}.
FT   DOMAIN      541    641       FANCI_HD2. {ECO:0000259|Pfam:PF14680}.
FT   DOMAIN      739    958       FANCI_S3. {ECO:0000259|Pfam:PF14677}.
FT   DOMAIN      969   1224       FANCI_S4. {ECO:0000259|Pfam:PF14678}.
FT   COILED     1305   1339       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1415 AA;  162485 MW;  28929A62C5819396 CRC64;
     MRSLGEKGRF DELELLIQNT PIEKLKETLK STMTRSEGIT YWNYLLRGFN PDSKDALAKR
     FECVRSFMDG LSSTELSYKQ TFDLITRLSQ DLATFPSEQL AWIVEHCMDG IRQGDAKCVG
     WKDLLPDALS LLLARPRFLL NGISIDGTEF RDTTVRSIAT MQWPASILTP IADMFKTINL
     SSGEIVTVLN KFSGALQELS PMELPALCFQ LFSVCSTASQ LIIPLLALEK YFHRNYYKRL
     FSDMCSNSTN LDSIDLFSDK ELREAEETIL HHLNYCTMYK LTEKHLAIML RNFLHMPDVI
     LTPFMLSAII SMTSINRDPE SARISHSILL PFLRNVIKNN EEERTLADYS VWYRDTLQRK
     QVDLQQVFMV LIDQNKDGKD VITPGLVHLV FYLLKSQSPK MHALAITFLT KFIRKRFIFG
     QGIIKLISEW MIVYQDQNQF SECLTLLSVA DTYTVSECIK PIQSLSGEQS MRMMNFILPL
     LKISNRVRDA LIDVLCKAMS SSGIQKRRMA IYGFCMILKQ LNNSNAVRQT SSATSFCTQH
     SISGYSIMTQ NTLGSRSNPQ RNFDMLTLEI IGMLRNCLQQ QFDIRCSLYE NLQRAVELNA
     KLVPHVLQVI DWHFRSFFDT PSAEDAGDDL DTVFRIRYDQ LLIQFVANCL AIFDRAPSGY
     DTREMNRLLS FCVDRMVANR LPLEEIHCKL LESLKALSDA SKKAYKHLKQ TAKNNSASTC
     NLTMNGVPVK TMCTQPDNIW DLAILDMLLH LLLDDVVAFA APEKTVLLRS NEPLVRYVLS
     VTASRVESIR LEPDYKQLAY SKRTFKQLTD ITKVIYERCI QRLPELWKNF DMQSAALATQ
     CFSECLKTAH ETYSKKFEDF VKSFDMASIK GSRNKEVVYT VQDVLDDFMM EYGTDDSICK
     NEFVSKLPVY LLESLEILLD HIDYQDRAAT ESYTWLLNFC SKNEILNSEM GLVHRMLFVQ
     RQKTHLGPFF DSVARQLGHV LGVQNEDVPS DSVELSLKSI STVTVESCLQ HLYAAVQKQL
     NDVDYFVTKA NNLNYKCQVV PEIDQIYWRG NLDSMDRSIC TQIIHISRTL LVLTNVCIPL
     GSLMDGLMKL LIQHYTCLKS LTKHYISSYT SDTSMENIRS TKFELLLRGV GKQLPANVYE
     LITYIEANTL DEEAQQHTKK RKVQAERAKV LRETRLIPKV IMVIEDFNKH IILLSKKTKS
     KNRLTDYLHL GTMRDFDIKS TDLRAAIERS ISDGRNISTE DSNADDQDED EDENENVEED
     DDAQSTTYPE DLEEQEDESL VVEKKKERRR RRAPSSEEED PQPKRKRGRK AAEQLEAEAE
     DEEEEEEEVE EEQPETTSKL RRNKKVEPKT KRSVAKATKK PEEQPSHESR TTKRSKAQAE
     KQAAEPAEEE LCVPEVPAEK KKPGRRLGIP RTVRK
//
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