ID B4R7X0_PHEZH Unreviewed; 1107 AA.
AC B4R7X0;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Amidohydrolase-related domain-containing protein {ECO:0000259|Pfam:PF01979};
GN OrderedLocusNames=PHZ_c1089 {ECO:0000313|EMBL:ACG77503.1};
OS Phenylobacterium zucineum (strain HLK1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Phenylobacterium.
OX NCBI_TaxID=450851 {ECO:0000313|EMBL:ACG77503.1, ECO:0000313|Proteomes:UP000001868};
RN [1] {ECO:0000313|EMBL:ACG77503.1, ECO:0000313|Proteomes:UP000001868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HLK1 {ECO:0000313|EMBL:ACG77503.1,
RC ECO:0000313|Proteomes:UP000001868};
RX PubMed=18700039; DOI=10.1186/1471-2164-9-386;
RA Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X.;
RT "Complete genome of Phenylobacterium zucineum - a novel facultative
RT intracellular bacterium isolated from human erythroleukemia cell line
RT K562.";
RL BMC Genomics 9:386-386(2008).
CC -!- SIMILARITY: Belongs to the TolB family.
CC {ECO:0000256|ARBA:ARBA00009820}.
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DR EMBL; CP000747; ACG77503.1; -; Genomic_DNA.
DR RefSeq; WP_012521649.1; NC_011144.1.
DR AlphaFoldDB; B4R7X0; -.
DR STRING; 450851.PHZ_c1089; -.
DR KEGG; pzu:PHZ_c1089; -.
DR eggNOG; COG0823; Bacteria.
DR eggNOG; COG1228; Bacteria.
DR HOGENOM; CLU_003547_0_0_5; -.
DR OrthoDB; 9758793at2; -.
DR Proteomes; UP000001868; Chromosome.
DR GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 3.
DR Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR006680; Amidohydro-rel.
DR InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR InterPro; IPR032466; Metal_Hydrolase.
DR InterPro; IPR011659; PD40.
DR PANTHER; PTHR36842; PROTEIN TOLB HOMOLOG; 1.
DR PANTHER; PTHR36842:SF1; TOL-PAL SYSTEM PROTEIN TOLB; 1.
DR Pfam; PF01979; Amidohydro_1; 1.
DR Pfam; PF07676; PD40; 5.
DR SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 2.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001868};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1107
FT /note="Amidohydrolase-related domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002821817"
FT DOMAIN 752..1085
FT /note="Amidohydrolase-related"
FT /evidence="ECO:0000259|Pfam:PF01979"
FT REGION 18..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1107 AA; 119123 MW; 21AF973E7916B71D CRC64;
MKSKLFAAVA ASAIVSAAWA QTPPPPQPPV QGPEDQAASP QNRQDPLPPQ TTGAAPAPAP
AADPAKWDVN NPPTVGQVRQ VPINVDEGTW MDLDVSPDGR TIAFALLGDI YVMPISGGTP
TRIAEGMAWE VQPRFSPDGK RIAFTSDRGG GDNIWVMNAD GSDKRQVTKE EFRLLNQPAW
SPDGRFIAAK KHFTTGRSLG TGEVWLYHVS GGGGVPLVKR PNEQHQKELG EPIFAPDGKS
IYFTRNITPG PIFEYAQDSN TDLFNIERYE LATGETSTAV AGPGGSVRPT PSPDGKKIAF
IRRERTQSRL YVKDLASGVE RKVYDDLDRD MQETWAVVGL YPNLAWTPDS KTLVFWAGGK
IRRVDADGAN ARVIPFRVND TRAVIEAPHP KVQVAPDRFA TKMTRYAAVS PDGRQVVYES
LGKLYVKPMA GGAARRLTRG DDGAFELFPA WSRDGRTIAF VSWTDAGLGR IKTVAASGGT
ARDVTNQPGH YARPQFSPDG RTIVFEKGEG GFLTARAWSE NPGVYRVPAS GGTPVRIARD
MGAPQFGADG ERVFMVASEK GKQQLVSTDL NGEAKRVHAQ GELVTDYSVS PDGALFAFRQ
NYEAHVMPLM PGGQEVAVDL KGGPMPVTRV SHGGATWIHW SDGGRRLHWS AGPTVYTAES
GSFFRSAPAG EAAAKFEPPT SGVSLSTEVA ADKPTGVTAL TGARIVTMAG NGAGTIDDGV
IVIRGDRIAA VGRRGEVAIP AGARTVDVTG KTIIPGLIDA HAHGPYGVDE MTPQQNWSLL
VNLALGTTTI HDPSTRAAEA FAAQEMQRAG KIVGPRIFST GEVVYGAKAA RSYAEINSLD
DALAHVRRLK AQGAHSVKNY NQPRREQRQQ VVEAARREGM QVVAEGGALF GQDMTLVADG
NSTLEHNIPQ MNLYEDVLSY FGQSSTYYTP TLVVTFGGLD GDRYWRAHTD VFDQPIVKAH
TPPAQLAAET VRRPIAPEGD YVDDDSAREA HKLAKRGVPV SIGAHGQQAG IGSHWELWSF
VRGGMSPVEA LRAGTIVPAR SLGMDADIGS LEAGKLADLV VLDADPTQDI RNSEKVHRVM
LGGRLYDPAT MNEVVTGDRK RAPYWWE
//
