ID B4RGL3_PHEZH Unreviewed; 515 AA.
AC B4RGL3;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=4-coumarate-CoA ligase {ECO:0000313|EMBL:ACG78919.1};
GN OrderedLocusNames=PHZ_c2510 {ECO:0000313|EMBL:ACG78919.1};
OS Phenylobacterium zucineum (strain HLK1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Phenylobacterium.
OX NCBI_TaxID=450851 {ECO:0000313|EMBL:ACG78919.1, ECO:0000313|Proteomes:UP000001868};
RN [1] {ECO:0000313|EMBL:ACG78919.1, ECO:0000313|Proteomes:UP000001868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HLK1 {ECO:0000313|EMBL:ACG78919.1,
RC ECO:0000313|Proteomes:UP000001868};
RX PubMed=18700039; DOI=10.1186/1471-2164-9-386;
RA Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X.;
RT "Complete genome of Phenylobacterium zucineum - a novel facultative
RT intracellular bacterium isolated from human erythroleukemia cell line
RT K562.";
RL BMC Genomics 9:386-386(2008).
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DR EMBL; CP000747; ACG78919.1; -; Genomic_DNA.
DR RefSeq; WP_012523057.1; NC_011144.1.
DR AlphaFoldDB; B4RGL3; -.
DR STRING; 450851.PHZ_c2510; -.
DR KEGG; pzu:PHZ_c2510; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_0_5; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000001868; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ACG78919.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001868}.
FT DOMAIN 19..369
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 425..499
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 515 AA; 55820 MW; 00BD2ABFD1F98843 CRC64;
MTAEELLSQE FGTIADVIRA QAAALQDKPA LIDARRTISY AELDALMDRI AAALQRDGVG
KADVAAVCAS TSVEYGATFF GVLRAGAIVA PLAPSSTPES LIVQLEDSGA KVFFLDKGVA
DHMAGVLDQV TAKRVSLDGS DVGQPFEEWL VPEGAKPVLH EIDPDQGFNI IYSSGTTGAP
KGIVQPHRMR WGQIRRGVYP PEAVSLVSTP LYSNTTLVSF LPTISNGGTV VLLPKFDVEQ
FLKLSEKHRV THAMLVPVQY RRLMAHPDFD KYDLSAFQMK FSTSAPFPAE LKAEVLRRWP
GGLVEYYGMT EGGGSCGLVC HEHPDKLHTV GKPLPGHDIR LIGEDGKEVA QGEIGEVVGR
SGAMMVGYHN QPGKTSEAEW WSPEGLRYIR TGDVGRFDED GFLTLMDRKK DMIISGGFNI
YPSDLEAEIV QHPAVLEAAV VGVASDAWGE TPVAFVALRP GQSVSAEELR AWVNGRLGKT
QRLADLKIVE GLPRSHIGKV LKRELRDGYR APAQA
//
