ID B4RH88_PHEZH Unreviewed; 739 AA.
AC B4RH88;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Dipeptidyl peptidase IV {ECO:0000313|EMBL:ACG79036.1};
GN OrderedLocusNames=PHZ_c2627 {ECO:0000313|EMBL:ACG79036.1};
OS Phenylobacterium zucineum (strain HLK1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Phenylobacterium.
OX NCBI_TaxID=450851 {ECO:0000313|EMBL:ACG79036.1, ECO:0000313|Proteomes:UP000001868};
RN [1] {ECO:0000313|EMBL:ACG79036.1, ECO:0000313|Proteomes:UP000001868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HLK1 {ECO:0000313|EMBL:ACG79036.1,
RC ECO:0000313|Proteomes:UP000001868};
RX PubMed=18700039; DOI=10.1186/1471-2164-9-386;
RA Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X.;
RT "Complete genome of Phenylobacterium zucineum - a novel facultative
RT intracellular bacterium isolated from human erythroleukemia cell line
RT K562.";
RL BMC Genomics 9:386-386(2008).
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DR EMBL; CP000747; ACG79036.1; -; Genomic_DNA.
DR RefSeq; WP_012523174.1; NC_011144.1.
DR AlphaFoldDB; B4RH88; -.
DR STRING; 450851.PHZ_c2627; -.
DR ESTHER; phezh-b4rh88; DPP4N_Peptidase_S9.
DR MEROPS; S09.009; -.
DR KEGG; pzu:PHZ_c2627; -.
DR eggNOG; COG1506; Bacteria.
DR HOGENOM; CLU_006105_2_1_5; -.
DR OrthoDB; 1094230at2; -.
DR Proteomes; UP000001868; Chromosome.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF193; DIPEPTIDYL PEPTIDASE 9; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001868};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..739
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002825440"
FT DOMAIN 129..452
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 542..738
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT REGION 24..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 739 AA; 81916 MW; DA27CEC2F8D63B24 CRC64;
MKLLIAALAA AVLAAPAAHA EQLPPPVPAK RVFESPDLNG PRARGVKLSP DGRSVTYIKV
RADDLTVTDL WIADVAGGEP RMLIDGKRLA PEARELSEAE KARRERAGVA TRGVVDYEWD
SQGRLILAPV EGDLYIYDLG SGQVRRLTRT PGDEIDAKVS PKGSFVSYVR DDDLYVTPAA
GGAERALTQG GTELKSWGTA EFIAQEEMDR HTGYWWSPDE ARIAVAHVDQ TGVDIVERPE
VGATGAKVVA QRYPRVGRPN AVVTLYVQDV ATGARTKVDL GDDPDIYLAR VDWSKDGRTL
YVQRQSRDQR RLDLIAVDPA TGKGRVILSE TSPHWVDITD DFKPLSDGTF LWSSEKSGFR
HLYLHRADGR LIRQVTKGAW PVAELRGVDE ARGVAIFTAN RDLPIERRLY EVSYRAPAEP
RALTPAGGWW SAEVARAGGA FVGTFEAPQT PPQTALYRAD GTRVRWIEEN RLAEGHPFHP
YAARLRTPEY GTIKAADGSP LWWSLRTPPG FDPAKKHPVI VQVYGGPGSA RVTRGWQNPE
DQILLDAGYI LFKLDNRGTP NRSTAFKTAI DRKLGQLEVD DQIAGAQFLK TLPYVDPERI
GVTGWSYGGY MTLLLLTAPD SPFKAGVAGA PVTDWTLYDT HYTERFMGTP KDNPEGYERS
EVVRRLDRLP AGSLLLIHGM ADDNVTFDHA TRVMFDLQAR GVPFETMVYP GLRHRGGWTP
MNRLHRAMQT LEFFDRKLR
//
