ID   B4RHK1_PHEZH            Unreviewed;       559 AA.
AC   B4RHK1;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=Aminopeptidase {ECO:0000313|EMBL:ACG77461.1};
GN   OrderedLocusNames=PHZ_c1047 {ECO:0000313|EMBL:ACG77461.1};
OS   Phenylobacterium zucineum (strain HLK1).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Phenylobacterium.
OX   NCBI_TaxID=450851 {ECO:0000313|EMBL:ACG77461.1, ECO:0000313|Proteomes:UP000001868};
RN   [1] {ECO:0000313|EMBL:ACG77461.1, ECO:0000313|Proteomes:UP000001868}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HLK1 {ECO:0000313|EMBL:ACG77461.1,
RC   ECO:0000313|Proteomes:UP000001868};
RX   PubMed=18700039; DOI=10.1186/1471-2164-9-386;
RA   Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X.;
RT   "Complete genome of Phenylobacterium zucineum - a novel facultative
RT   intracellular bacterium isolated from human erythroleukemia cell line
RT   K562.";
RL   BMC Genomics 9:386-386(2008).
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DR   EMBL; CP000747; ACG77461.1; -; Genomic_DNA.
DR   RefSeq; WP_012521607.1; NC_011144.1.
DR   AlphaFoldDB; B4RHK1; -.
DR   STRING; 450851.PHZ_c1047; -.
DR   KEGG; pzu:PHZ_c1047; -.
DR   eggNOG; COG2234; Bacteria.
DR   HOGENOM; CLU_019932_2_1_5; -.
DR   OrthoDB; 9778250at2; -.
DR   Proteomes; UP000001868; Chromosome.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd04821; PA_M28_1_2; 1.
DR   Gene3D; 3.50.30.30; -; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR045175; M28_fam.
DR   InterPro; IPR046450; PA_dom_sf.
DR   InterPro; IPR007484; Peptidase_M28.
DR   PANTHER; PTHR12147:SF26; ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1; 1.
DR   PANTHER; PTHR12147; METALLOPEPTIDASE M28 FAMILY MEMBER; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   SUPFAM; SSF52025; PA domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   4: Predicted;
KW   Aminopeptidase {ECO:0000313|EMBL:ACG77461.1};
KW   Hydrolase {ECO:0000313|EMBL:ACG77461.1};
KW   Protease {ECO:0000313|EMBL:ACG77461.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001868};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..559
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002825488"
FT   DOMAIN          304..511
FT                   /note="Peptidase M28"
FT                   /evidence="ECO:0000259|Pfam:PF04389"
SQ   SEQUENCE   559 AA;  60214 MW;  0B7F08176ECCFA79 CRC64;
     MKALIVAAAL LAAAPAAPVL AREATADTGP ISAQRISDIT RELASDAYFG RAPGGPGEQK
     TVDYLVEQFR ALGLEPAGDD GTYVQEVQLY RFQTAPGGAY RLTAPGLDRT LATQTDLRVE
     TQRPTPRIRI ENAPLVFVGY GVTAPERGWD DFKGVDLKGK IAVILINDPD FEAKAGEPVA
     GKFGGKAATY YARWTYKYEE AVRQGALGAL IVHETAGAAY PWSTVIAGGG ESYDVVRKDP
     AADRLLLQGW MQRDLAVELF KASGLDFEAQ KARARTAAFT PVELKGAAFS ADYGNAVEKL
     TSRNVLGAVR GSRHPDETVM YSSHWDAYGV GAPDAEGRTI RPGALDSATG VAGVIEVARA
     FKAGPRPERT VLFGLWTGEE RGLLGSEFYA QTMSYPVGKM VASIAFDTLQ PLGPTRDVVL
     IGSGQNQLED LLKAAAAKRG RTITPDPRPE RALNYRADHF SFGRRGVPTL LLMALAGGPD
     LVEGGRAAGD RWVEDFTARC YHQTCDRWEP THDYSGAAAD VNLAYEIGLR LANSRAWPDW
     NEGSELKPIR AETAAARRP
//