ID B4SAU9_PELPB Unreviewed; 211 AA.
AC B4SAU9;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=pre-crRNA processing endonuclease {ECO:0000256|PIRNR:PIRNR029950};
DE EC=3.1.-.- {ECO:0000256|PIRNR:PIRNR029950};
GN OrderedLocusNames=Ppha_1658 {ECO:0000313|EMBL:ACF43895.1};
OS Pelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1).
OC Bacteria; Chlorobiota; Chlorobiia; Chlorobiales; Chlorobiaceae;
OC Chlorobium/Pelodictyon group; Pelodictyon.
OX NCBI_TaxID=324925 {ECO:0000313|EMBL:ACF43895.1, ECO:0000313|Proteomes:UP000002724};
RN [1] {ECO:0000313|EMBL:ACF43895.1, ECO:0000313|Proteomes:UP000002724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5477 / BU-1 {ECO:0000313|Proteomes:UP000002724};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Liu Z., Li T., Zhao F., Overmann J.,
RA Bryant D.A., Richardson P.;
RT "Complete sequence of Pelodictyon phaeoclathratiforme BU-1.";
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: CRISPR (clustered regularly interspaced short palindromic
CC repeat) is an adaptive immune system that provides protection against
CC mobile genetic elements (viruses, transposable elements and conjugative
CC plasmids). CRISPR clusters contain spacers, sequences complementary to
CC antecedent mobile elements, and target invading nucleic acids. CRISPR
CC clusters are transcribed and processed into CRISPR RNA (crRNA).
CC {ECO:0000256|PIRNR:PIRNR029950}.
CC -!- SIMILARITY: Belongs to the CRISPR-associated protein Cas5 family.
CC Subtype I-C/Dvulg subfamily. {ECO:0000256|PIRNR:PIRNR029950}.
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DR EMBL; CP001110; ACF43895.1; -; Genomic_DNA.
DR RefSeq; WP_012508382.1; NC_011060.1.
DR AlphaFoldDB; B4SAU9; -.
DR STRING; 324925.Ppha_1658; -.
DR KEGG; pph:Ppha_1658; -.
DR eggNOG; ENOG502Z82V; Bacteria.
DR HOGENOM; CLU_086014_0_0_10; -.
DR OrthoDB; 9787787at2; -.
DR Proteomes; UP000002724; Chromosome.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-UniRule.
DR GO; GO:0043571; P:maintenance of CRISPR repeat elements; IEA:UniProtKB-UniRule.
DR CDD; cd09752; Cas5_I-C; 1.
DR Gene3D; 3.30.70.2660; -; 1.
DR InterPro; IPR021124; CRISPR-assoc_prot_Cas5.
DR InterPro; IPR013422; CRISPR-assoc_prot_Cas5_N.
DR InterPro; IPR010155; CRISPR-assoc_prot_Cas5d.
DR NCBIfam; TIGR01876; cas_Cas5d; 1.
DR NCBIfam; TIGR02593; CRISPR_cas5; 1.
DR Pfam; PF09704; Cas_Cas5d; 1.
DR PIRSF; PIRSF029950; Cas_CT1134; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118,
KW ECO:0000256|PIRNR:PIRNR029950};
KW Endonuclease {ECO:0000256|PIRNR:PIRNR029950};
KW Hydrolase {ECO:0000256|PIRNR:PIRNR029950};
KW Nuclease {ECO:0000256|PIRNR:PIRNR029950};
KW Reference proteome {ECO:0000313|Proteomes:UP000002724};
KW RNA-binding {ECO:0000256|PIRNR:PIRNR029950}.
SQ SEQUENCE 211 AA; 24868 MW; 0283249F572A61F5 CRC64;
MSYGIKLRVW GDYALFTRPE MKVERVSYDV MTPSAARGIL EAIYWKPSIR WIIDRIHVLK
PIRFENIRRN EVAKKTSLNR VDMVGQYPIS IIVDDSDTRQ QRASMVLRDV EYIIEAHFYF
SMKEDNNEGK HLDIFTRRAK AGQCFHRPYF GCREFPVNFE WCVDIPKSLL SGEQDLGYML
HDIDFENNMT ARFFRAIMHN GIINCKQEAV S
//
