ID B4U5P6_HYDS0 Unreviewed; 710 AA.
AC B4U5P6;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Anaerobic ribonucleoside-triphosphate reductase {ECO:0000313|EMBL:ACG58086.1};
DE EC=1.17.4.2 {ECO:0000313|EMBL:ACG58086.1};
GN ORFNames=HY04AAS1_1401 {ECO:0000313|EMBL:ACG58086.1};
OS Hydrogenobaculum sp. (strain Y04AAS1).
OC Bacteria; Aquificota; Aquificae; Aquificales; Aquificaceae;
OC Hydrogenobaculum.
OX NCBI_TaxID=380749 {ECO:0000313|EMBL:ACG58086.1};
RN [1] {ECO:0000313|EMBL:ACG58086.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Y04AAS1 {ECO:0000313|EMBL:ACG58086.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Kiss H., Brettin T.,
RA Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Resenback A.-L., Mead D.;
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACG58086.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Y04AAS1 {ECO:0000313|EMBL:ACG58086.1};
RX PubMed=19136599; DOI=10.1128/JB.01645-08;
RA Reysenbach A.L., Hamamura N., Podar M., Griffiths E., Ferreira S.,
RA Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A.,
RA Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.;
RT "Complete and draft genome sequences of six members of the Aquificales.";
RL J. Bacteriol. 191:1992-1993(2009).
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DR EMBL; CP001130; ACG58086.1; -; Genomic_DNA.
DR AlphaFoldDB; B4U5P6; -.
DR STRING; 380749.HY04AAS1_1401; -.
DR KEGG; hya:HY04AAS1_1401; -.
DR eggNOG; COG1328; Bacteria.
DR HOGENOM; CLU_002707_0_2_0; -.
DR OrthoDB; 9804622at2; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd01675; RNR_III; 1.
DR Gene3D; 3.20.70.20; -; 1.
DR InterPro; IPR005144; ATP-cone_dom.
DR InterPro; IPR012833; NrdD.
DR NCBIfam; TIGR02487; NrdD; 1.
DR PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR Pfam; PF03477; ATP-cone; 1.
DR Pfam; PF13597; NRDD; 1.
DR SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00492}; Oxidoreductase {ECO:0000313|EMBL:ACG58086.1}.
FT DOMAIN 18..113
FT /note="ATP-cone"
FT /evidence="ECO:0000259|PROSITE:PS51161"
SQ SEQUENCE 710 AA; 80976 MW; A3AA8EB0D99D33BA CRC64;
MELFFDVKTS LPRFTSLPRV LKRDNVTEVD FDVNRIEKAI EKAFDAVSEF KGIDNAYIKD
IAKEVISAIC RRGLSVITIE QIQDIVEETI IAHGFSKVAR AYIVYRRERE RVRETEAGLV
NLENTTIDID KLVKNYISQE DWRTFENSNS SFSYPGLYLH VAGSVIANYT LKNVYPEHIR
KAHESADIHI HDLSHGIVAY CAGWSMEDLL RKGFRGGYGQ IVAGPAKHLS ALTGQMVNFL
GVMQMEFAGA QAFNSVDTFL APFVRVDNLD YQDVKQLIQQ MVFAMNVPSR WGSQPPFINF
TFDWTVPEDM KNKPVIIGGE ERPDIGYYGD FQKEMDVINK AFIEVMLEGD YAGRIFSFPI
PTYNITKDFD YYGENAKLLW KMTAKYGTPY FQNFVSSSLK PGDVRSMCCR LQLDLRELRS
RMGGLFGAAD KTGSIGVVTI NLPRIGYLAK TKEEYFSMLF EAMDIAKESL EIKRRVVERN
LKAGLMPYAA SYLNSFDNHF STIGIVGMHE SLLNFLGKGI NTKEGKAFAI EILQKMRERL
SLYQELTGHL YNLEATPAEG TSYRLAKHDK KRFPDIITSG ENEPYYTNST LLPVGYTEDP
FEVLEHQKDL QTLYTGGTVV HMFLGESPNE NTLPEFIRKA FETYPIPYLT ITPTFSVCPN
HGYINGEHFN CPVCNAPSEV YSRVVGYYRP VQRWNAGKKE EFKDRLEYML
//
