ID B4V7W9_9ACTN Unreviewed; 229 AA.
AC B4V7W9;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Mycothiol maleylpyruvate isomerase {ECO:0000313|EMBL:AKL65670.1};
DE SubName: Full=Mycothiol-dependent maleylpyruvate isomerase {ECO:0000313|EMBL:EDX24056.1};
GN ORFNames=M444_09970 {ECO:0000313|EMBL:AKL65670.1}, SSAG_03933
GN {ECO:0000313|EMBL:EDX24056.1};
OS Streptomyces sp. Mg1.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=465541 {ECO:0000313|EMBL:EDX24056.1, ECO:0000313|Proteomes:UP000005764};
RN [1] {ECO:0000313|EMBL:EDX24056.1, ECO:0000313|Proteomes:UP000005764}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mg1 {ECO:0000313|EMBL:EDX24056.1,
RC ECO:0000313|Proteomes:UP000005764};
RG The Broad Institute Genome Sequencing Platform;
RA Fischbach M., Ward D., Young S., Jaffe D., Gnerre S., Berlin A., Heiman D.,
RA Hepburn T., Sykes S., Mehta T., Alvarado L., Kodira C.D., Straight P.,
RA Clardy J., Hung D., Kolter R., Mekalanos J., Walker S., Walsh C.T.,
RA Lander E., Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Streptomyces sp. Mg1.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AKL65670.1, ECO:0000313|Proteomes:UP000035653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mg1 {ECO:0000313|EMBL:AKL65670.1,
RC ECO:0000313|Proteomes:UP000035653};
RX PubMed=23908282;
RA Hoefler B.C., Konganti K., Straight P.D.;
RT "De Novo Assembly of the Streptomyces sp. Strain Mg1 Genome Using PacBio
RT Single-Molecule Sequencing.";
RL Genome Announc. 1:e00535-13(2013).
RN [3] {ECO:0000313|EMBL:AKL65670.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Mg1 {ECO:0000313|EMBL:AKL65670.1};
RA Hoefler B.C., Straight P.D.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP011664; AKL65670.1; -; Genomic_DNA.
DR EMBL; DS570406; EDX24056.1; -; Genomic_DNA.
DR RefSeq; WP_008741083.1; NZ_DS570406.1.
DR AlphaFoldDB; B4V7W9; -.
DR STRING; 465541.M444_09970; -.
DR KEGG; strm:M444_09970; -.
DR PATRIC; fig|465541.12.peg.2202; -.
DR eggNOG; ENOG5031RF6; Bacteria.
DR HOGENOM; CLU_077935_0_0_11; -.
DR OrthoDB; 5118203at2; -.
DR Proteomes; UP000005764; Unassembled WGS sequence.
DR Proteomes; UP000035653; Chromosome.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 3.30.1050.20; -; 1.
DR Gene3D; 1.20.120.450; dinb family like domain; 1.
DR InterPro; IPR034660; DinB/YfiT-like.
DR InterPro; IPR017517; Maleyloyr_isom.
DR InterPro; IPR010872; MDMPI_C-term_domain.
DR InterPro; IPR024344; MDMPI_metal-binding.
DR InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR NCBIfam; TIGR03083; maleylpyruvate isomerase family mycothiol-dependent enzyme; 1.
DR Pfam; PF07398; MDMPI_C; 1.
DR Pfam; PF11716; MDMPI_N; 1.
DR SUPFAM; SSF109854; DinB/YfiT-like putative metalloenzymes; 1.
DR SUPFAM; SSF55718; SCP-like; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000313|EMBL:EDX24056.1};
KW Pyruvate {ECO:0000313|EMBL:EDX24056.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000035653}.
FT DOMAIN 11..139
FT /note="Mycothiol-dependent maleylpyruvate isomerase metal-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF11716"
FT DOMAIN 147..227
FT /note="MDMPI C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07398"
SQ SEQUENCE 229 AA; 24797 MW; B419BDD8EEA52ABB CRC64;
MTDHVHDLRS VREAGDRLLI DVAKLDNAAL AGESHLPGWT RGHILAHVAR NADALVNVLE
GRPMYESAEA RDSDIERDAP RPLEVQLADV REASERFLAQ EGADQDWSRT VELRNGVTDL
ASNVPFRRLV EIELHHVDLN IGYALEDLPD EFTRREIDFL ADRWSGRPEV PPTALVAADG
RSWRTGSAGD PAVTVSGTAA GLLAWLAGRG DKGASLTTAG GPLPALPPL
//
