ID B4VF72_9ACTN Unreviewed; 575 AA.
AC B4VF72;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:AKL66698.1};
GN ORFNames=M444_16260 {ECO:0000313|EMBL:AKL66698.1}, SSAG_06442
GN {ECO:0000313|EMBL:EDX26609.1};
OS Streptomyces sp. Mg1.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=465541 {ECO:0000313|EMBL:EDX26609.1, ECO:0000313|Proteomes:UP000005764};
RN [1] {ECO:0000313|EMBL:EDX26609.1, ECO:0000313|Proteomes:UP000005764}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mg1 {ECO:0000313|EMBL:EDX26609.1,
RC ECO:0000313|Proteomes:UP000005764};
RG The Broad Institute Genome Sequencing Platform;
RA Fischbach M., Ward D., Young S., Jaffe D., Gnerre S., Berlin A., Heiman D.,
RA Hepburn T., Sykes S., Mehta T., Alvarado L., Kodira C.D., Straight P.,
RA Clardy J., Hung D., Kolter R., Mekalanos J., Walker S., Walsh C.T.,
RA Lander E., Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Streptomyces sp. Mg1.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AKL66698.1, ECO:0000313|Proteomes:UP000035653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mg1 {ECO:0000313|EMBL:AKL66698.1,
RC ECO:0000313|Proteomes:UP000035653};
RX PubMed=23908282;
RA Hoefler B.C., Konganti K., Straight P.D.;
RT "De Novo Assembly of the Streptomyces sp. Strain Mg1 Genome Using PacBio
RT Single-Molecule Sequencing.";
RL Genome Announc. 1:e00535-13(2013).
RN [3] {ECO:0000313|EMBL:AKL66698.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Mg1 {ECO:0000313|EMBL:AKL66698.1};
RA Hoefler B.C., Straight P.D.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP011664; AKL66698.1; -; Genomic_DNA.
DR EMBL; DS570460; EDX26609.1; -; Genomic_DNA.
DR RefSeq; WP_008743621.1; NZ_DS570460.1.
DR AlphaFoldDB; B4VF72; -.
DR STRING; 465541.M444_16260; -.
DR KEGG; strm:M444_16260; -.
DR PATRIC; fig|465541.12.peg.3505; -.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG2203; Bacteria.
DR HOGENOM; CLU_495986_0_0_11; -.
DR OrthoDB; 23692at2; -.
DR Proteomes; UP000005764; Unassembled WGS sequence.
DR Proteomes; UP000035653; Chromosome.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000035653}.
FT DOMAIN 208..267
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 279..331
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 445..575
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT REGION 386..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 184..211
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 575 AA; 62404 MW; 2331B5FB00E911BD CRC64;
METESEPYVR LATLRQLHRV VAELNTARSL ADTLQTVVDG IVGGLGYELA CVNLVRPDGD
LVVAAFAGDP AAEALITGRV GSRASWDRRL TMGENWDGLR FIPHSEGWVL LEDDVPQWHT
DGPDPRFEDE WHPEDRLYAP MYATGGELLG VISVDRPRNG RRPGAWGREA LQMYAFQAAI
AISNARLRAN MQRALVRLER EQQALRASEE SFRQAFEYAP SGMAIAEMGG DQHGRLLRTN
DALCRLLGRP ASVLRRYSFS DLVHPEDIGT LLRTSAEGGR AELRLGRRDG TYVWVSLRNS
VVADAADGPR FLLTHVEDIE ERKRHELQLA HRASHDSLTG LPNSAELRSR LGARLCRRPQ
SARATAIEAL DAAYEGRGPV PETVGAGEHG FRPDGPHTFA GPDPFDFPGG PAGLGPPGGG
PGEAGPYDHH VHAVAPATDV DDGTKGLAVL FCDLDGFKSI NDRFGHHTGD AVLIEVARRL
TTGVRDGDTV ARLGGDEFVV LADGLGAADA ADLAVRLRNA IIPPIRVDGR PVRVGASFGI
GWASCGMSAD EVLRSADQRM YIEKRSRSKA HRRAG
//
